CS88692A3 - Process for preparing quinoline derivatives - Google Patents

Process for preparing quinoline derivatives Download PDF

Info

Publication number
CS88692A3
CS88692A3 CS92886A CS88692A CS88692A3 CS 88692 A3 CS88692 A3 CS 88692A3 CS 92886 A CS92886 A CS 92886A CS 88692 A CS88692 A CS 88692A CS 88692 A3 CS88692 A3 CS 88692A3
Authority
CS
Czechoslovakia
Prior art keywords
group
carbon atoms
alkyl
formula
phenyl
Prior art date
Application number
CS92886A
Other languages
Czech (cs)
English (en)
Inventor
Arnold Harry Ratcliffe
Emyr Glyn Williams
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of CS88692A3 publication Critical patent/CS88692A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS92886A 1990-08-09 1992-03-24 Process for preparing quinoline derivatives CS88692A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909017479A GB9017479D0 (en) 1990-08-09 1990-08-09 Process
PCT/GB1991/001287 WO1992002508A1 (en) 1990-08-09 1991-07-30 Process for the manufacture of quinoline derivatives

Publications (1)

Publication Number Publication Date
CS88692A3 true CS88692A3 (en) 1992-10-14

Family

ID=10680406

Family Applications (1)

Application Number Title Priority Date Filing Date
CS92886A CS88692A3 (en) 1990-08-09 1992-03-24 Process for preparing quinoline derivatives

Country Status (15)

Country Link
EP (1) EP0495948A1 (pt)
JP (1) JPH05501728A (pt)
KR (1) KR920702357A (pt)
CN (1) CN1058965A (pt)
AU (1) AU8309091A (pt)
CA (1) CA2047249A1 (pt)
CS (1) CS88692A3 (pt)
FI (1) FI921319A (pt)
GB (2) GB9017479D0 (pt)
HU (1) HUT60490A (pt)
IE (1) IE912406A1 (pt)
IL (1) IL98833A0 (pt)
PT (1) PT98607A (pt)
WO (1) WO1992002508A1 (pt)
ZA (1) ZA915567B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246944A (en) * 1991-08-13 1993-09-21 Merck & Co., Inc. Quinoline angiotensin ii antagonists incorporating a substituted benzyl element
US5484955A (en) * 1992-07-06 1996-01-16 Takeda Chemical Industries, Ltd. Tri-higher alkyl tin azide and its use
US6608048B2 (en) 2000-03-28 2003-08-19 Wyeth Holdings Tricyclic protein kinase inhibitors
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (pt) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos
LT3046584T (lt) 2013-09-16 2017-10-10 Astrazeneca Ab Terapinės polimerinės nanodalelės ir jų gamybos būdai ir panaudojimas

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US4920132A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
NZ234854A (en) * 1989-08-11 1993-02-25 Ici Plc Quinoline derivatives, preparation, intermediates and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
JPH05501728A (ja) 1993-04-02
KR920702357A (ko) 1992-09-03
FI921319A0 (fi) 1992-03-26
PT98607A (pt) 1992-06-30
CN1058965A (zh) 1992-02-26
IE912406A1 (en) 1992-02-12
ZA915567B (en) 1992-07-29
WO1992002508A1 (en) 1992-02-20
FI921319A (fi) 1992-03-26
HUT60490A (en) 1992-09-28
HU9200933D0 (en) 1992-05-28
CA2047249A1 (en) 1992-02-10
EP0495948A1 (en) 1992-07-29
AU8309091A (en) 1992-03-02
GB9017479D0 (en) 1990-09-26
IL98833A0 (en) 1992-07-15
GB9115250D0 (en) 1991-08-28

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