IE912406A1 - Process - Google Patents
ProcessInfo
- Publication number
- IE912406A1 IE912406A1 IE240691A IE240691A IE912406A1 IE 912406 A1 IE912406 A1 IE 912406A1 IE 240691 A IE240691 A IE 240691A IE 240691 A IE240691 A IE 240691A IE 912406 A1 IE912406 A1 IE 912406A1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- alkyl
- hydrogen
- ethyl
- cyano
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909017479A GB9017479D0 (en) | 1990-08-09 | 1990-08-09 | Process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IE912406A1 true IE912406A1 (en) | 1992-02-12 |
Family
ID=10680406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE240691A IE912406A1 (en) | 1990-08-09 | 1991-07-09 | Process |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0495948A1 (pt) |
| JP (1) | JPH05501728A (pt) |
| KR (1) | KR920702357A (pt) |
| CN (1) | CN1058965A (pt) |
| AU (1) | AU8309091A (pt) |
| CA (1) | CA2047249A1 (pt) |
| CS (1) | CS88692A3 (pt) |
| FI (1) | FI921319A (pt) |
| GB (2) | GB9017479D0 (pt) |
| HU (1) | HUT60490A (pt) |
| IE (1) | IE912406A1 (pt) |
| IL (1) | IL98833A0 (pt) |
| PT (1) | PT98607A (pt) |
| WO (1) | WO1992002508A1 (pt) |
| ZA (1) | ZA915567B (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5246944A (en) * | 1991-08-13 | 1993-09-21 | Merck & Co., Inc. | Quinoline angiotensin ii antagonists incorporating a substituted benzyl element |
| US5484955A (en) * | 1992-07-06 | 1996-01-16 | Takeda Chemical Industries, Ltd. | Tri-higher alkyl tin azide and its use |
| US6608048B2 (en) | 2000-03-28 | 2003-08-19 | Wyeth Holdings | Tricyclic protein kinase inhibitors |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| PT3004138T (pt) | 2013-06-05 | 2024-06-18 | Bausch Health Ireland Ltd | Agonistas ultrapuros de guanilato ciclase c, método de produção e utilização dos mesmos |
| LT3046584T (lt) | 2013-09-16 | 2017-10-10 | Astrazeneca Ab | Terapinės polimerinės nanodalelės ir jų gamybos būdai ir panaudojimas |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
| US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| NZ234854A (en) * | 1989-08-11 | 1993-02-25 | Ici Plc | Quinoline derivatives, preparation, intermediates and pharmaceutical compositions thereof |
-
1990
- 1990-08-09 GB GB909017479A patent/GB9017479D0/en active Pending
-
1991
- 1991-07-09 IE IE240691A patent/IE912406A1/en unknown
- 1991-07-15 IL IL98833A patent/IL98833A0/xx unknown
- 1991-07-16 GB GB919115250A patent/GB9115250D0/en active Pending
- 1991-07-16 ZA ZA915567A patent/ZA915567B/xx unknown
- 1991-07-17 CA CA002047249A patent/CA2047249A1/en not_active Abandoned
- 1991-07-24 CN CN91105053A patent/CN1058965A/zh active Pending
- 1991-07-30 HU HU92933A patent/HUT60490A/hu unknown
- 1991-07-30 KR KR1019920700813A patent/KR920702357A/ko not_active Application Discontinuation
- 1991-07-30 AU AU83090/91A patent/AU8309091A/en not_active Abandoned
- 1991-07-30 JP JP3513216A patent/JPH05501728A/ja active Pending
- 1991-07-30 EP EP91914106A patent/EP0495948A1/en not_active Withdrawn
- 1991-07-30 WO PCT/GB1991/001287 patent/WO1992002508A1/en not_active Application Discontinuation
- 1991-08-08 PT PT98607A patent/PT98607A/pt not_active Application Discontinuation
-
1992
- 1992-03-24 CS CS92886A patent/CS88692A3/cs unknown
- 1992-03-26 FI FI921319A patent/FI921319A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05501728A (ja) | 1993-04-02 |
| KR920702357A (ko) | 1992-09-03 |
| FI921319A0 (fi) | 1992-03-26 |
| PT98607A (pt) | 1992-06-30 |
| CN1058965A (zh) | 1992-02-26 |
| CS88692A3 (en) | 1992-10-14 |
| ZA915567B (en) | 1992-07-29 |
| WO1992002508A1 (en) | 1992-02-20 |
| FI921319A (fi) | 1992-03-26 |
| HUT60490A (en) | 1992-09-28 |
| HU9200933D0 (en) | 1992-05-28 |
| CA2047249A1 (en) | 1992-02-10 |
| EP0495948A1 (en) | 1992-07-29 |
| AU8309091A (en) | 1992-03-02 |
| GB9017479D0 (en) | 1990-09-26 |
| IL98833A0 (en) | 1992-07-15 |
| GB9115250D0 (en) | 1991-08-28 |
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