CS249111B2 - Method of 1,2,4-oxadiazin's new derivatives production - Google Patents

Method of 1,2,4-oxadiazin's new derivatives production Download PDF

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Publication number
CS249111B2
CS249111B2 CS806736A CS673680A CS249111B2 CS 249111 B2 CS249111 B2 CS 249111B2 CS 806736 A CS806736 A CS 806736A CS 673680 A CS673680 A CS 673680A CS 249111 B2 CS249111 B2 CS 249111B2
Authority
CS
Czechoslovakia
Prior art keywords
carbon atoms
alkyl
compounds
phenyl
alkoxy
Prior art date
Application number
CS806736A
Other languages
Czech (cs)
English (en)
Inventor
Kalman Takacs
Ilona Kiss
Antal Simay
Nagy P Literati
Maria Hetyey
Marian Ecsery
Jozsef Szegi
Sandor Viragh
Nagy S Juhasz
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to CS851950A priority Critical patent/CS249541B2/cs
Publication of CS249111B2 publication Critical patent/CS249111B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/02—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having two nitrogen atoms and only one oxygen atom
    • C07D273/04—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CS806736A 1979-10-11 1980-10-06 Method of 1,2,4-oxadiazin's new derivatives production CS249111B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS851950A CS249541B2 (cs) 1979-10-11 1985-03-20 Způsob výroby nových derivátů 1,2,4-oxadiazinu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79CI1914A HU180708B (en) 1979-10-11 1979-10-11 Process for preparing new 1,2,4-oxadiazine derivatives

Publications (1)

Publication Number Publication Date
CS249111B2 true CS249111B2 (en) 1987-03-12

Family

ID=10994765

Family Applications (1)

Application Number Title Priority Date Filing Date
CS806736A CS249111B2 (en) 1979-10-11 1980-10-06 Method of 1,2,4-oxadiazin's new derivatives production

Country Status (25)

Country Link
US (1) US4308270A (hu)
JP (1) JPS5663970A (hu)
AT (1) AT373247B (hu)
BE (1) BE885634A (hu)
CA (1) CA1159828A (hu)
CH (1) CH649540A5 (hu)
CS (1) CS249111B2 (hu)
DD (1) DD153551A5 (hu)
DE (1) DE3037747A1 (hu)
DK (1) DK149106C (hu)
ES (1) ES8106714A1 (hu)
FR (1) FR2467204B1 (hu)
GB (1) GB2062628B (hu)
GR (1) GR71205B (hu)
HU (1) HU180708B (hu)
IL (1) IL61176A (hu)
IT (1) IT1129306B (hu)
LU (1) LU82823A1 (hu)
NL (1) NL8005587A (hu)
NO (1) NO153652C (hu)
PL (2) PL129378B1 (hu)
RO (3) RO81210A (hu)
SE (1) SE448234B (hu)
SU (1) SU1087520A1 (hu)
YU (2) YU41739B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179951B (en) * 1979-10-11 1983-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 1,2,4-oxadiazolin-5-one derivatives and pharmaceutical compositions containing thereof
EP1622883A4 (en) * 2003-04-10 2008-04-02 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
WO2017031325A1 (en) * 2015-08-18 2017-02-23 Forum Pharmaceuticals Inc. Oxadiazine compounds and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053825A (hu) * 1963-03-22
DE1795839C3 (de) * 1964-03-02 1981-09-03 Chinoin Gyógyszer és Vegyészeti Termékek Gyára RT, 1045 Budapest Verfahren zur Herstellung von 3,5-disubstituierten 1,2,4-Oxadiazolderivaten
DE1545658C3 (de) * 1964-03-02 1981-04-23 Chinoin Gyógyszer és Vegyészeti Termékek Gyára RT, 1045 Budapest Verfahren zur Herstellung von 3,5-disubstituierten 1,2,4-Oxadiazolderivaten
IT1043838B (it) * 1971-04-22 1980-02-29 Poli Ind Chimica Spa 1 2 3 4 tetraidroisochinoline e processo per la loro preparazione
US4154598A (en) * 1975-09-11 1979-05-15 Philagro Herbicidal 1,2,4-oxadiazin-5-one compositions
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
HU179951B (en) * 1979-10-11 1983-01-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 1,2,4-oxadiazolin-5-one derivatives and pharmaceutical compositions containing thereof

Also Published As

Publication number Publication date
SE8007026L (sv) 1981-04-12
YU42063B (en) 1988-04-30
GR71205B (hu) 1983-04-11
CH649540A5 (de) 1985-05-31
RO81210B (ro) 1983-01-30
YU259580A (en) 1983-04-30
RO81210A (ro) 1983-02-01
PL129081B1 (en) 1984-03-31
DD153551A5 (de) 1982-01-13
ES495820A0 (es) 1981-09-16
ES8106714A1 (es) 1981-09-16
HU180708B (en) 1983-04-29
JPH0215547B2 (hu) 1990-04-12
ATA501280A (de) 1983-05-15
RO85269B (ro) 1984-10-30
DE3037747A1 (de) 1981-06-11
YU41739B (en) 1987-12-31
IT8068556A0 (it) 1980-10-09
PL232264A1 (hu) 1982-03-29
GB2062628A (en) 1981-05-28
FR2467204B1 (fr) 1986-03-28
JPS5663970A (en) 1981-05-30
NO153652C (no) 1986-05-07
PL227211A1 (hu) 1981-11-27
LU82823A1 (de) 1981-02-02
RO85268A (ro) 1984-09-29
NO153652B (no) 1986-01-20
BE885634A (fr) 1981-02-02
GB2062628B (en) 1983-08-03
FR2467204A1 (fr) 1981-04-17
US4308270A (en) 1981-12-29
DK149106C (da) 1986-06-09
AT373247B (de) 1983-12-27
IT1129306B (it) 1986-06-04
PL129378B1 (en) 1984-05-31
DK149106B (da) 1986-01-27
IL61176A (en) 1984-05-31
YU291182A (en) 1983-04-30
CA1159828A (en) 1984-01-03
RO85269A (ro) 1984-09-29
DK429680A (da) 1981-04-12
NO803045L (no) 1981-04-13
RO85268B (ro) 1984-10-30
NL8005587A (nl) 1981-04-14
SU1087520A1 (ru) 1984-04-23
IL61176A0 (en) 1980-11-30
SE448234B (sv) 1987-02-02

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