CS241122B2 - Method of ergoline derivatives production - Google Patents

Method of ergoline derivatives production Download PDF

Info

Publication number
CS241122B2
CS241122B2 CS826422A CS642282A CS241122B2 CS 241122 B2 CS241122 B2 CS 241122B2 CS 826422 A CS826422 A CS 826422A CS 642282 A CS642282 A CS 642282A CS 241122 B2 CS241122 B2 CS 241122B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
carbon atoms
formula
amide
acid amide
Prior art date
Application number
CS826422A
Other languages
Czech (cs)
English (en)
Other versions
CS642282A2 (en
Inventor
Gerhard Sauer
Gregor Haffer
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS642282A2 publication Critical patent/CS642282A2/cs
Publication of CS241122B2 publication Critical patent/CS241122B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS826422A 1981-09-03 1982-09-03 Method of ergoline derivatives production CS241122B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3135305A DE3135305C2 (de) 1981-09-03 1981-09-03 Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen

Publications (2)

Publication Number Publication Date
CS642282A2 CS642282A2 (en) 1985-07-16
CS241122B2 true CS241122B2 (en) 1986-03-13

Family

ID=6141023

Family Applications (1)

Application Number Title Priority Date Filing Date
CS826422A CS241122B2 (en) 1981-09-03 1982-09-03 Method of ergoline derivatives production

Country Status (17)

Country Link
US (1) US4748248A (es)
EP (1) EP0074921B1 (es)
JP (1) JPS5855483A (es)
AT (1) ATE11289T1 (es)
AU (1) AU555576B2 (es)
CA (1) CA1175813A (es)
CS (1) CS241122B2 (es)
DD (1) DD203544A5 (es)
DE (2) DE3135305C2 (es)
DK (1) DK161646C (es)
ES (1) ES8305361A1 (es)
GR (1) GR76897B (es)
HU (1) HU186969B (es)
IE (1) IE53437B1 (es)
IL (1) IL66679A (es)
SU (1) SU1272988A3 (es)
YU (1) YU199282A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
US20060171795A1 (en) * 2005-01-28 2006-08-03 Cromwell Stephen D Substantial embedment of metallic debris
JP2010119349A (ja) * 2008-11-20 2010-06-03 Shinichi Okamoto 即席のパンなどの穀物粉加工食品の製造方法
JP6856532B2 (ja) 2015-01-20 2021-04-07 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ エルゴリン化合物およびその使用
BR112017015510A2 (pt) * 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
MX2019014272A (es) 2017-06-01 2020-12-11 Xoc Pharmaceuticals Inc Compuestos policiclicos y usos de los mismos.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
DK161646C (da) 1992-01-06
AU555576B2 (en) 1986-10-02
US4748248A (en) 1988-05-31
AU8786382A (en) 1983-03-10
ATE11289T1 (de) 1985-02-15
YU199282A (en) 1985-03-20
DE3261963D1 (en) 1985-02-28
CS642282A2 (en) 1985-07-16
ES515428A0 (es) 1983-05-01
SU1272988A3 (ru) 1986-11-23
CA1175813A (en) 1984-10-09
HU186969B (en) 1985-10-28
IL66679A0 (en) 1982-12-31
IE53437B1 (en) 1988-11-09
EP0074921A1 (en) 1983-03-23
DD203544A5 (de) 1983-10-26
EP0074921B1 (en) 1985-01-16
IL66679A (en) 1986-04-29
DK161646B (da) 1991-07-29
JPS5855483A (ja) 1983-04-01
ES8305361A1 (es) 1983-05-01
DK368382A (da) 1983-03-04
GR76897B (es) 1984-09-04
DE3135305A1 (de) 1983-03-10
IE822156L (en) 1983-03-03
DE3135305C2 (de) 1983-07-21
JPH0239511B2 (es) 1990-09-05

Similar Documents

Publication Publication Date Title
IE49991B1 (en) New(ergolinyl)-n',n'-diethylurea derivatives,a process for their manufacture and their use as medicaments
DK144160B (da) Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner
CS241122B2 (en) Method of ergoline derivatives production
CS241071B2 (en) Method of substituted ergolines production
US3755328A (en) Process for preparing ergot alkaloids
US4417051A (en) Process for the preparation of 8α-substituted 6-methylergolines
EP1114050B1 (en) Process for the production of a naphthyridine carboxylic acid derivative ( methanesulfonate sesquihydrate )
DK143804B (da) Analogifremgangsmaade til fremstilling af ergopeptinderivater
US5401748A (en) 2,14-disubstituted ergolines, their production and use in pharmaceutical compositions
US6121449A (en) Process for preparing carboxamido-4-azasteroids
CS253742B2 (en) Process for preparing beta-carbolines
CS256364B2 (en) Method of 12 and 13 bromergoline's new derivatives production
Hermkens et al. Intramolecular Pictet-Spengler reaction of N-alkoxytryptophans and tryptamines. 2. Synthesis of corynanthe alkaloid derivatives containing a tetrahydro-1, 2-oxazine as the D ring
SU493965A3 (ru) Способ получени д-2-замещенных-6-алкил8-замещенных эрголинов
US3846433A (en) Process for preparing ergot alkaloids
SU469251A3 (ru) Способ получени гетероциклических соединений
SU372813A1 (ru) Способ получения алкалоидов
SU542475A3 (ru) Способ получени алкалоидов спорыньи
GB2177090A (en) 10???-methoxy-6-methyl-ergoline derivatives
IE46595B1 (en) 4-thia-2,6-diazabicyclo(3.2.0)heptane derivatives
US3141887A (en) Process for the preparation of
CS262581B1 (cs) 2-Trffluoracetylderfvéty ergolinu a způsob jejich výroby
GB2065113A (en) Ergoline derivatives, their production and pharmaceutical compositions containing them
NL7907122A (nl) Bromeringswerkwijze.
DK146564B (da) Lysergsyrederivater