CS241086B2 - New/amido/ n-substituted bleomycines production - Google Patents
New/amido/ n-substituted bleomycines production Download PDFInfo
- Publication number
- CS241086B2 CS241086B2 CS843468A CS346884A CS241086B2 CS 241086 B2 CS241086 B2 CS 241086B2 CS 843468 A CS843468 A CS 843468A CS 346884 A CS346884 A CS 346884A CS 241086 B2 CS241086 B2 CS 241086B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- propyl
- amino
- methyl
- amido
- substituted
- Prior art date
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- 125000003368 amide group Chemical group 0.000 title claims abstract description 30
- 238000004519 manufacturing process Methods 0.000 title description 2
- OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical class N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 claims abstract description 43
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- 238000000034 method Methods 0.000 claims abstract description 28
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 11
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 9
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract description 9
- 125000005843 halogen group Chemical group 0.000 claims abstract description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 6
- 125000001424 substituent group Chemical group 0.000 claims abstract description 5
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- 239000007858 starting material Substances 0.000 claims description 4
- CYFQYXXVLSBMQJ-UHFFFAOYSA-N 1,4-bis(phenylmethoxy)cyclohexa-2,4-diene-1-carbaldehyde Chemical compound C(C1=CC=CC=C1)OC1(C=O)CC=C(C=C1)OCC1=CC=CC=C1 CYFQYXXVLSBMQJ-UHFFFAOYSA-N 0.000 claims description 3
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- 210000003456 pulmonary alveoli Anatomy 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- BEOOHQFXGBMRKU-UHFFFAOYSA-N sodium cyanoborohydride Chemical compound [Na+].[B-]C#N BEOOHQFXGBMRKU-UHFFFAOYSA-N 0.000 description 1
- 206010041823 squamous cell carcinoma Diseases 0.000 description 1
- 125000004646 sulfenyl group Chemical group S(*)* 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C21—METALLURGY OF IRON
- C21B—MANUFACTURE OF IRON OR STEEL
- C21B2100/00—Handling of exhaust gases produced during the manufacture of iron or steel
- C21B2100/40—Gas purification of exhaust gases to be recirculated or used in other metallurgical processes
- C21B2100/44—Removing particles, e.g. by scrubbing, dedusting
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/20—Recycling
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58084605A JPS59210100A (ja) | 1983-05-14 | 1983-05-14 | 新規アミドｎ置換ブレオマイシン類の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS346884A2 CS346884A2 (en) | 1985-06-13 |
| CS241086B2 true CS241086B2 (en) | 1986-03-13 |
Family
ID=13835313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS843468A CS241086B2 (en) | 1983-05-14 | 1984-05-10 | New/amido/ n-substituted bleomycines production |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS59210100A (enrdf_load_stackoverflow) |
| KR (1) | KR910001725B1 (enrdf_load_stackoverflow) |
| AT (1) | AT380886B (enrdf_load_stackoverflow) |
| CA (1) | CA1276400C (enrdf_load_stackoverflow) |
| CS (1) | CS241086B2 (enrdf_load_stackoverflow) |
| DK (1) | DK237184A (enrdf_load_stackoverflow) |
| ES (1) | ES8506308A1 (enrdf_load_stackoverflow) |
| HU (1) | HU189110B (enrdf_load_stackoverflow) |
| YU (1) | YU43845B (enrdf_load_stackoverflow) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58116496A (ja) * | 1981-12-29 | 1983-07-11 | Nippon Kayaku Co Ltd | アミドｎ置換ブレオマイシン類 |
| JPS636078A (ja) * | 1986-06-27 | 1988-01-12 | Nippon Zeon Co Ltd | 半導体用薬剤の収納容器部材 |
-
1983
- 1983-05-14 JP JP58084605A patent/JPS59210100A/ja active Granted
-
1984
- 1984-05-08 CA CA000453841A patent/CA1276400C/en not_active Expired - Lifetime
- 1984-05-10 CS CS843468A patent/CS241086B2/cs unknown
- 1984-05-10 ES ES532369A patent/ES8506308A1/es not_active Expired
- 1984-05-11 HU HU841839A patent/HU189110B/hu not_active IP Right Cessation
- 1984-05-11 DK DK237184A patent/DK237184A/da not_active Application Discontinuation
- 1984-05-12 KR KR1019840002574A patent/KR910001725B1/ko not_active Expired
- 1984-05-14 AT AT0157084A patent/AT380886B/de not_active IP Right Cessation
- 1984-05-14 YU YU837/84A patent/YU43845B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR840009304A (ko) | 1984-12-26 |
| AT380886B (de) | 1986-07-25 |
| DK237184D0 (da) | 1984-05-11 |
| CS346884A2 (en) | 1985-06-13 |
| YU43845B (en) | 1989-12-31 |
| JPS59210100A (ja) | 1984-11-28 |
| KR910001725B1 (ko) | 1991-03-22 |
| JPH03879B2 (enrdf_load_stackoverflow) | 1991-01-09 |
| ES532369A0 (es) | 1985-07-01 |
| CA1276400C (en) | 1990-11-13 |
| ES8506308A1 (es) | 1985-07-01 |
| HU189110B (en) | 1986-06-30 |
| HUT34223A (en) | 1985-02-28 |
| YU83784A (en) | 1987-02-28 |
| ATA157084A (de) | 1985-12-15 |
| DK237184A (da) | 1984-11-15 |
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