CS241014B2 - Method of 9-aminopyrido-(1,2-a)pyrimidine derivatives production - Google Patents

Method of 9-aminopyrido-(1,2-a)pyrimidine derivatives production Download PDF

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Publication number
CS241014B2
CS241014B2 CS789090A CS909078A CS241014B2 CS 241014 B2 CS241014 B2 CS 241014B2 CS 789090 A CS789090 A CS 789090A CS 909078 A CS909078 A CS 909078A CS 241014 B2 CS241014 B2 CS 241014B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
converted
carboxylic acid
optically active
Prior art date
Application number
CS789090A
Other languages
Czech (cs)
English (en)
Other versions
CS909078A2 (en
Inventor
Istvan Hermecz
Zoltan Meszaros
Tibor Breining
Sandor Virag
Lelle Vasvari
Agnes Horvath
Gabor Nagy
Attila Mandi
Tamas Szuets
Istvan Bitter
Gyula Sebestyen
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS909078A2 publication Critical patent/CS909078A2/cs
Publication of CS241014B2 publication Critical patent/CS241014B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS789090A 1977-12-29 1978-12-28 Method of 9-aminopyrido-(1,2-a)pyrimidine derivatives production CS241014B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1795A HU180439B (en) 1977-12-29 1977-12-29 Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives

Publications (2)

Publication Number Publication Date
CS909078A2 CS909078A2 (en) 1985-06-13
CS241014B2 true CS241014B2 (en) 1986-03-13

Family

ID=10994684

Family Applications (1)

Application Number Title Priority Date Filing Date
CS789090A CS241014B2 (en) 1977-12-29 1978-12-28 Method of 9-aminopyrido-(1,2-a)pyrimidine derivatives production

Country Status (28)

Country Link
US (1) US4260612A (xx)
JP (1) JPS54112895A (xx)
AR (1) AR221712A1 (xx)
AT (1) AT374476B (xx)
AU (1) AU520803B2 (xx)
BE (1) BE873141A (xx)
CA (1) CA1154766A (xx)
CH (1) CH641800A5 (xx)
CS (1) CS241014B2 (xx)
DD (1) DD143910A5 (xx)
DE (1) DE2854112A1 (xx)
DK (1) DK585478A (xx)
ES (1) ES476837A1 (xx)
FI (1) FI65620C (xx)
FR (1) FR2413390A1 (xx)
GB (1) GB2011408B (xx)
GR (1) GR67312B (xx)
HU (1) HU180439B (xx)
IL (1) IL56132A (xx)
IT (1) IT7869932A0 (xx)
LU (1) LU80659A1 (xx)
NL (1) NL7812479A (xx)
NO (1) NO150280C (xx)
PL (1) PL119517B1 (xx)
PT (1) PT68924A (xx)
SE (1) SE434056B (xx)
SU (1) SU906379A3 (xx)
YU (2) YU296378A (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178452B (en) * 1979-05-11 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 9-substituted amino-4-oxo-6,7-dihydro-4h-pyrido/1,2-a/pyrimidine derivatives
HU183330B (en) * 1981-02-13 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new of 2,4,8-triazaphenalenium-salts
US5352795A (en) * 1986-03-07 1994-10-04 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
HU201551B (en) * 1988-02-03 1990-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786056A (en) * 1954-05-03 1957-03-19 Merck & Co Inc Acylamido-hydroxy pteridines and preparation thereof
GB1147760A (en) * 1965-06-17 1969-04-10 Sterling Drug Inc Heterocyclic nitrogen compounds
AT299212B (de) * 1966-11-02 1972-06-12 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
GB1141249A (en) * 1967-05-25 1969-01-29 Parke Davis & Co New quinazoline compounds and methods for their production
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
JPS50149698A (xx) * 1974-05-25 1975-11-29
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones

Also Published As

Publication number Publication date
NO150280C (no) 1984-09-19
ES476837A1 (es) 1979-06-16
NL7812479A (nl) 1979-07-03
SE7813225L (sv) 1979-06-30
NO150280B (no) 1984-06-12
FR2413390B1 (xx) 1982-06-11
US4260612A (en) 1981-04-07
FI784014A (fi) 1979-06-30
AR221712A1 (es) 1981-03-13
YU278082A (en) 1983-10-31
FR2413390A1 (fr) 1979-07-27
SU906379A3 (ru) 1982-02-15
IL56132A0 (en) 1979-03-12
AU520803B2 (en) 1982-02-25
PT68924A (en) 1979-01-01
GR67312B (xx) 1981-06-29
CH641800A5 (de) 1984-03-15
GB2011408B (en) 1982-06-30
PL119517B1 (en) 1982-01-30
IL56132A (en) 1982-02-28
SE434056B (sv) 1984-07-02
DK585478A (da) 1979-06-30
AT374476B (de) 1984-04-25
HU180439B (en) 1983-03-28
FI65620C (fi) 1984-06-11
CS909078A2 (en) 1985-06-13
JPS54112895A (en) 1979-09-04
IT7869932A0 (it) 1978-12-22
ATA901078A (de) 1983-09-15
BE873141A (fr) 1979-04-17
PL212205A1 (xx) 1980-02-25
DD143910A5 (de) 1980-09-17
YU296378A (en) 1983-10-31
NO784392L (no) 1979-07-02
LU80659A1 (de) 1979-04-13
FI65620B (fi) 1984-02-29
GB2011408A (en) 1979-07-11
AU4262878A (en) 1981-06-18
DE2854112A1 (de) 1979-07-12
CA1154766A (en) 1983-10-04

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