CS240972B2 - Production method of new phenethanolamines - Google Patents
Production method of new phenethanolamines Download PDFInfo
- Publication number
- CS240972B2 CS240972B2 CS835860A CS586083A CS240972B2 CS 240972 B2 CS240972 B2 CS 240972B2 CS 835860 A CS835860 A CS 835860A CS 586083 A CS586083 A CS 586083A CS 240972 B2 CS240972 B2 CS 240972B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- group
- amino
- methyl
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Battery Electrode And Active Subsutance (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH478782 | 1982-08-10 | ||
CH289783 | 1983-05-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CS586083A2 CS586083A2 (en) | 1985-06-13 |
CS240972B2 true CS240972B2 (en) | 1986-03-13 |
Family
ID=25691672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS835860A CS240972B2 (en) | 1982-08-10 | 1983-08-09 | Production method of new phenethanolamines |
Country Status (18)
Country | Link |
---|---|
US (1) | US4585796A (fr) |
EP (1) | EP0101069B1 (fr) |
AU (1) | AU570640B2 (fr) |
CA (1) | CA1258454A (fr) |
CS (1) | CS240972B2 (fr) |
DE (1) | DE3363177D1 (fr) |
DK (1) | DK350083A (fr) |
ES (1) | ES524823A0 (fr) |
FI (1) | FI80030C (fr) |
HU (1) | HU191867B (fr) |
IE (1) | IE55896B1 (fr) |
IL (1) | IL69438A (fr) |
MC (1) | MC1536A1 (fr) |
NO (1) | NO832867L (fr) |
NZ (1) | NZ205132A (fr) |
PH (1) | PH18647A (fr) |
PT (1) | PT77173B (fr) |
ZW (1) | ZW15483A1 (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1219865A (fr) * | 1982-05-14 | 1987-03-31 | Leo Alig | Derives de phenethanolamine d'aziridine |
CA1258454A (fr) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
CA1262729A (fr) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
GB8415377D0 (en) * | 1984-06-15 | 1984-07-18 | Beecham Group Plc | Compounds |
GB8418472D0 (en) * | 1984-07-19 | 1984-08-22 | Beecham Group Plc | Compounds |
PT82120B (en) * | 1985-03-01 | 1988-06-16 | Beecham Group Plc | Process for preparing veterinary formulations containing ethanolamine derivatives |
DE3662521D1 (de) * | 1985-04-16 | 1989-04-27 | Hoffmann La Roche | Phenethanol amine derivatives |
CA1287061C (fr) * | 1986-06-27 | 1991-07-30 | Roche Holding Ltd. | Derives de pyridineethanolamines |
DE3718638A1 (de) * | 1987-06-04 | 1988-12-22 | Thomae Gmbh Dr K | Neue phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
RU2147574C1 (ru) * | 1991-08-23 | 2000-04-20 | Эн-Пи-Эс Фармасьютикалз, Инк. | Арилалкиламины, композиции, способы лечения и диагностики, способы идентификации соединения |
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
DE122005000033I1 (de) | 1994-10-21 | 2005-09-29 | Nps Pharma Inc | Kalzium-Rezeptor aktive Verbindungen. |
ATE430123T1 (de) * | 1996-05-01 | 2009-05-15 | Nps Pharma Inc | Inorganische am ionen-rezeptor aktive verbindungen |
CN1902177A (zh) | 2003-09-22 | 2007-01-24 | 万有制药株式会社 | 新哌啶衍生物 |
US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
BRPI0614649A2 (pt) | 2005-08-11 | 2011-04-12 | Amylin Pharmaceuticals Inc | polipeptìdeos hìbridos com propriedades selecionáveis |
CA2617649A1 (fr) | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Polypeptides hybrides presentant des proprietes selectionnables |
AU2006304836A1 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent |
EP2698157B1 (fr) | 2006-09-22 | 2015-05-20 | Merck Sharp & Dohme Corp. | Procédé de traitement utilisant des inhibiteurs de synthèse d'acide gras |
AU2009261248A1 (en) | 2008-06-19 | 2009-12-23 | Banyu Pharmaceutical Co., Ltd. | Spirodiamine-diarylketoxime derivative |
WO2010051236A1 (fr) | 2008-10-30 | 2010-05-06 | Merck Sharp & Dohme Corp. | Antagonistes d'isonicotinamide des récepteurs de l'orexine |
EP2379562A1 (fr) | 2008-12-16 | 2011-10-26 | Schering Corporation | Dérivés de pyranone bicyclique comme agonistes du récepteur de l'acide nicotinique |
US20110245209A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
AR088352A1 (es) | 2011-10-19 | 2014-05-28 | Merck Sharp & Dohme | Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina |
WO2014022528A1 (fr) | 2012-08-02 | 2014-02-06 | Merck Sharp & Dohme Corp. | Composés tricycliques antidiabétiques |
US11866631B2 (en) | 2019-04-29 | 2024-01-09 | Ecolab Usa Inc. | Oxygenated aminophenol compounds and methods for preventing monomer polymerization |
EP4232489A1 (fr) | 2020-10-21 | 2023-08-30 | Ecolab USA Inc. | Polymères d'(hydroxyalkyl)aminophénol et procédés d'utilisation |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD45721A (fr) * | ||||
GB1109924A (en) * | 1965-11-29 | 1968-04-18 | Roche Products Ltd | Novel substituted diphenylalkyl amines and a process for the manufacture thereof |
US3732300A (en) * | 1966-09-23 | 1973-05-08 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
US4101579A (en) * | 1969-02-06 | 1978-07-18 | Allen & Hanburys Limited | Phenethanolamine ethers |
DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
DE2023829C3 (de) * | 1970-05-15 | 1979-06-21 | Pfizer Corp., Colon (Panama) | Kernsubstituierte 3-Phenoxy-lphenoxyalkyl-amino-propan-2-oIe, Verfahren zu ihrer Herstellung sowie Arzneimittel |
US3867455A (en) * | 1970-06-02 | 1975-02-18 | Allen & Hanburys Ltd | Preparation of phenylaminoethanols |
US4137328A (en) * | 1970-07-18 | 1979-01-30 | Pfizer Inc. | Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants |
GB1394001A (en) * | 1972-12-22 | 1975-05-14 | Pfizer Ltd | 2-morpholino or homomorpholino 1-3-trifluoromethylphenyl propanes |
CA1145767A (fr) * | 1978-07-03 | 1983-05-03 | Jack Mills | Phenethanolamines, composes les contenant et methode pour maigrir |
CA1145766A (fr) * | 1978-07-03 | 1983-05-03 | Jack Mills | Phenethanolamines ayant des proprietes optiques et methode pour augmenter la contractilite cardiaque |
DK268579A (da) * | 1978-07-03 | 1980-01-04 | Lilly Co Eli | Fremgangsmaade til fremstilling af phenetamolaminer |
DE3061334D1 (en) * | 1979-06-16 | 1983-01-20 | Beecham Group Plc | Ethanamine derivatives, their preparation and use in pharmaceutical compositions |
DE3061205D1 (en) * | 1979-06-16 | 1983-01-05 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
DE3062216D1 (en) * | 1979-09-06 | 1983-04-07 | Beecham Group Plc | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them |
ATE2265T1 (de) * | 1979-10-25 | 1983-02-15 | Beecham Group Plc | Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen. |
ATE14222T1 (de) * | 1979-11-15 | 1985-07-15 | Beecham Group Plc | Sekundaere aethanolamine, ihre herstellung und ihre verwendung in pharmazeutischen zusammensetzungen. |
EP0040000B1 (fr) * | 1980-05-08 | 1983-10-12 | Beecham Group Plc | Dérivés d'aryléthanolamine, leur préparation et leur utilisation dans des compositions pharmaceutiques |
DE3162756D1 (en) * | 1980-05-22 | 1984-04-26 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
GB2084577B (en) * | 1980-09-26 | 1984-05-02 | Beecham Group Ltd | Secondary amines |
DE3264364D1 (en) * | 1981-03-06 | 1985-08-01 | Beecham Group Plc | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions |
EP0061907B1 (fr) * | 1981-03-31 | 1984-08-01 | Beecham Group Plc | Amines secondaires, leur préparation, compositions pharmaceutiques les contenant et leur utilisation |
EP0063004A1 (fr) * | 1981-04-09 | 1982-10-20 | Beecham Group Plc | Amines secondaires, procédé pour leur préparation et compositions pharmaceutiques les contenant |
EP0068669A1 (fr) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Phényléthanolamines secondaires, procédés de leur préparation et leur application pharmaceutique |
DE3271132D1 (en) * | 1981-07-11 | 1986-06-19 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
DE3267406D1 (en) * | 1981-07-11 | 1985-12-19 | Beecham Group Plc | Secondary phenyl ethanol amines and their pharmaceutical use |
CA1219865A (fr) * | 1982-05-14 | 1987-03-31 | Leo Alig | Derives de phenethanolamine d'aziridine |
CA1258454A (fr) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
-
1983
- 1983-07-04 CA CA000431762A patent/CA1258454A/fr not_active Expired
- 1983-07-06 ZW ZW154/83A patent/ZW15483A1/xx unknown
- 1983-07-29 DK DK350083A patent/DK350083A/da not_active Application Discontinuation
- 1983-08-01 US US06/518,990 patent/US4585796A/en not_active Expired - Fee Related
- 1983-08-03 NZ NZ205132A patent/NZ205132A/en unknown
- 1983-08-04 AU AU17588/83A patent/AU570640B2/en not_active Ceased
- 1983-08-04 IL IL69438A patent/IL69438A/xx unknown
- 1983-08-08 FI FI832844A patent/FI80030C/fi not_active IP Right Cessation
- 1983-08-08 HU HU832789A patent/HU191867B/hu not_active IP Right Cessation
- 1983-08-09 PH PH29376A patent/PH18647A/en unknown
- 1983-08-09 MC MC831652A patent/MC1536A1/fr unknown
- 1983-08-09 CS CS835860A patent/CS240972B2/cs unknown
- 1983-08-09 IE IE1872/83A patent/IE55896B1/en not_active IP Right Cessation
- 1983-08-09 NO NO832867A patent/NO832867L/no unknown
- 1983-08-09 ES ES524823A patent/ES524823A0/es active Granted
- 1983-08-09 PT PT77173A patent/PT77173B/pt not_active IP Right Cessation
- 1983-08-10 EP EP83107908A patent/EP0101069B1/fr not_active Expired
- 1983-08-10 DE DE8383107908T patent/DE3363177D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IE831872L (en) | 1984-02-10 |
PT77173A (en) | 1983-09-01 |
NO832867L (no) | 1984-02-13 |
EP0101069A1 (fr) | 1984-02-22 |
DK350083D0 (da) | 1983-07-29 |
FI80030C (fi) | 1990-04-10 |
EP0101069B1 (fr) | 1986-04-23 |
FI80030B (fi) | 1989-12-29 |
CA1258454A (fr) | 1989-08-15 |
ES8505333A1 (es) | 1985-06-01 |
ES524823A0 (es) | 1985-06-01 |
CS586083A2 (en) | 1985-06-13 |
FI832844A0 (fi) | 1983-08-08 |
PT77173B (en) | 1986-03-20 |
AU570640B2 (en) | 1988-03-24 |
IE55896B1 (en) | 1991-02-14 |
AU1758883A (en) | 1984-02-16 |
MC1536A1 (fr) | 1984-05-25 |
PH18647A (en) | 1985-08-23 |
HU191867B (en) | 1987-04-28 |
US4585796A (en) | 1986-04-29 |
IL69438A (en) | 1986-08-31 |
ZW15483A1 (en) | 1985-01-30 |
DE3363177D1 (de) | 1986-05-28 |
DK350083A (da) | 1984-02-11 |
NZ205132A (en) | 1987-03-06 |
IL69438A0 (en) | 1983-11-30 |
FI832844A (fi) | 1984-02-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CS240972B2 (en) | Production method of new phenethanolamines | |
EP0210849B1 (fr) | 2-Hydroxy-3-phénoxypropylamines | |
JP3232337B2 (ja) | 4−[2−(2−ヒドロキシ−2−フエニル−エチルアミノ)エトキシ]フエニル酢酸およびその生前駆体、その製造方法、およびそれを含有する調剤学的組成物 | |
EP0140243B1 (fr) | Phénoxypropanolamines | |
KR100954237B1 (ko) | 퍼록시솜 증식자 활성화 수용체 델타 리간드 티아졸 화합물및 이를 함유하는 의약, 화장품 및 건강식품 조성물 | |
US20210386751A1 (en) | Treatment with p2x3 modulators | |
NO844501L (no) | Oksazolidiner. | |
JPH03503643A (ja) | N‐複素環プロピリデン‐1,1‐ビスホスホン酸、その製法および薬剤組成物 | |
EP0094595B1 (fr) | Dérivés de l'aziridine et de la phényléthanolamine | |
WO1999002512A1 (fr) | Dl-2,3-diaryl-2h-1-benzopyrans | |
SE429339B (sv) | 3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper | |
EP0164700B1 (fr) | Bis-(bêta-hydroxyphényléthyl)amines | |
TW200521126A (en) | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders | |
EP0142102B1 (fr) | Amines tertiaires | |
HUT72632A (en) | Pharmacologically active alpha-[tertiary-aminomethyl]-benzenemethanol derivatives, pharmaceutical compositions containing them and process for their preparation | |
PT93357A (pt) | Processo para a preparacao de tiofenos | |
CN116478050B (zh) | 一种手性芳基丙酸衍生物及其药物组合物和用途 | |
JP2926168B2 (ja) | 含硫黄化合物 | |
KR820001303B1 (ko) | 펜에탄올아민의 제조방법 | |
PL94264B1 (fr) | ||
WO1998040354A1 (fr) | Inhibiteurs de lta4 hydrolase | |
NZ272976A (en) | Bicyclic oxazole(thiazole)substituted (thio)ethers | |
WO1992015594A1 (fr) | Derives de benzamide | |
JPS6029379B2 (ja) | 新規なヒドロキサム酸化合物およびこの化合物を主成分とする尿路結石症治療剤 |