FI832844A - Nya fenyletanolaminer - Google Patents

Nya fenyletanolaminer Download PDF

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Publication number
FI832844A
FI832844A FI832844A FI832844A FI832844A FI 832844 A FI832844 A FI 832844A FI 832844 A FI832844 A FI 832844A FI 832844 A FI832844 A FI 832844A FI 832844 A FI832844 A FI 832844A
Authority
FI
Finland
Prior art keywords
ananaminer
nya
surface ananaminer
nya surface
Prior art date
Application number
FI832844A
Other languages
English (en)
Other versions
FI832844A0 (fi
FI80030C (fi
FI80030B (fi
Inventor
Leo Alig
Marcel Myller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI832844A0 publication Critical patent/FI832844A0/fi
Publication of FI832844A publication Critical patent/FI832844A/fi
Application granted granted Critical
Publication of FI80030B publication Critical patent/FI80030B/fi
Publication of FI80030C publication Critical patent/FI80030C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Battery Electrode And Active Subsutance (AREA)
FI832844A 1982-08-10 1983-08-08 Foerfarande foer framstaellning av terapeutiskt aktiva fenyletanolaminderivat. FI80030C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH478782 1982-08-10
CH478782 1982-08-10
CH289783 1983-05-27
CH289783 1983-05-27

Publications (4)

Publication Number Publication Date
FI832844A0 FI832844A0 (fi) 1983-08-08
FI832844A true FI832844A (fi) 1984-02-11
FI80030B FI80030B (fi) 1989-12-29
FI80030C FI80030C (fi) 1990-04-10

Family

ID=25691672

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832844A FI80030C (fi) 1982-08-10 1983-08-08 Foerfarande foer framstaellning av terapeutiskt aktiva fenyletanolaminderivat.

Country Status (18)

Country Link
US (1) US4585796A (fi)
EP (1) EP0101069B1 (fi)
AU (1) AU570640B2 (fi)
CA (1) CA1258454A (fi)
CS (1) CS240972B2 (fi)
DE (1) DE3363177D1 (fi)
DK (1) DK350083A (fi)
ES (1) ES8505333A1 (fi)
FI (1) FI80030C (fi)
HU (1) HU191867B (fi)
IE (1) IE55896B1 (fi)
IL (1) IL69438A (fi)
MC (1) MC1536A1 (fi)
NO (1) NO832867L (fi)
NZ (1) NZ205132A (fi)
PH (1) PH18647A (fi)
PT (1) PT77173B (fi)
ZW (1) ZW15483A1 (fi)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
GB8415377D0 (en) * 1984-06-15 1984-07-18 Beecham Group Plc Compounds
GB8418472D0 (en) * 1984-07-19 1984-08-22 Beecham Group Plc Compounds
PT82120B (en) * 1985-03-01 1988-06-16 Beecham Group Plc Process for preparing veterinary formulations containing ethanolamine derivatives
DE3662521D1 (de) * 1985-04-16 1989-04-27 Hoffmann La Roche Phenethanol amine derivatives
CA1287061C (en) * 1986-06-27 1991-07-30 Roche Holding Ltd. Pyridine ethanolamine derivatives
DE3718638A1 (de) * 1987-06-04 1988-12-22 Thomae Gmbh Dr K Neue phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
FI892341A (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
JP2728564B2 (ja) * 1991-08-23 1998-03-18 エヌピーエス・ファーマシウティカルズ・インコーポレイテッド カルシウム受容体活性化分子
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5321036A (en) * 1993-02-10 1994-06-14 Bristol-Myers Squibb Company Thiazole and oxazole-based β3 adrenergic receptor agonists
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
RU2195446C2 (ru) 1994-12-08 2002-12-27 Эн-Пи-Эс Фармасьютикалз, Инк. Соединения, обладающие активностью в отношении рецептора кальция (варианты), фармацевтическая композиция и способы лечения (варианты)
DE69722934T2 (de) 1996-05-01 2004-05-27 NPS Pharmaceuticals, Inc., Salt Lake City Verbindungen , die auf anorganische ionen-rezeptoren wirken
AU2004274309B2 (en) 2003-09-22 2010-04-08 Msd K.K. Novel piperidine derivative
US20090286723A1 (en) 2005-02-11 2009-11-19 Amylin Pharmaceuticals, Inc. Hybrid Polypeptides with Selectable Properties
US7737155B2 (en) 2005-05-17 2010-06-15 Schering Corporation Nitrogen-containing heterocyclic compounds and methods of use thereof
EP2330125A3 (en) 2005-08-11 2012-12-12 Amylin Pharmaceuticals, Inc. Hybrid polypeptides with selectable properties
RU2008119687A (ru) 2005-10-21 2009-11-27 Новартис АГ (CH) Комбинации органических соединений
EP2083831B1 (en) 2006-09-22 2013-12-25 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
WO2009154132A1 (ja) 2008-06-19 2009-12-23 萬有製薬株式会社 スピロジアミン-ジアリールケトオキシム誘導体
CN102272103B (zh) 2008-10-30 2015-10-21 默沙东公司 异烟酰胺食欲素受体拮抗剂
WO2010075068A1 (en) 2008-12-16 2010-07-01 Schering Corporation Pyridopyrimidine derivatives and methods of use thereof
EP2379562A1 (en) 2008-12-16 2011-10-26 Schering Corporation Bicyclic pyranone derivatives as nicotinic acid receptor agonists
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AR088352A1 (es) 2011-10-19 2014-05-28 Merck Sharp & Dohme Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
US9527875B2 (en) 2012-08-02 2016-12-27 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
WO2020223224A1 (en) 2019-04-29 2020-11-05 Ecolab Usa Inc. Oxygenated aminophenol compounds and methods for preventing monomer polymerization
CA3196257A1 (en) 2020-10-21 2022-04-28 Ashish Dhawan Alkoxylated (hydroxyalkyl)aminophenol polymers and methods of use

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD45721A (fi) *
GB1109924A (en) * 1965-11-29 1968-04-18 Roche Products Ltd Novel substituted diphenylalkyl amines and a process for the manufacture thereof
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
US3732300A (en) * 1966-09-23 1973-05-08 Allen & Hanburys Ltd Phenylaminoethanol derivatives
US4101579A (en) * 1969-02-06 1978-07-18 Allen & Hanburys Limited Phenethanolamine ethers
DE1922003C3 (de) * 1969-04-30 1979-10-11 Boehringer Mannheim Gmbh, 6800 Mannheim N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz
DE2023829C3 (de) * 1970-05-15 1979-06-21 Pfizer Corp., Colon (Panama) Kernsubstituierte 3-Phenoxy-lphenoxyalkyl-amino-propan-2-oIe, Verfahren zu ihrer Herstellung sowie Arzneimittel
US3867455A (en) * 1970-06-02 1975-02-18 Allen & Hanburys Ltd Preparation of phenylaminoethanols
US4137328A (en) * 1970-07-18 1979-01-30 Pfizer Inc. Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants
GB1394001A (en) * 1972-12-22 1975-05-14 Pfizer Ltd 2-morpholino or homomorpholino 1-3-trifluoromethylphenyl propanes
IL57670A (en) * 1978-07-03 1982-11-30 Lilly Co Eli Phenethanolamines,their preparation and pharmaceutical formulations comprising them
CA1142954A (en) * 1978-07-03 1983-03-15 Jack Mills Phenethanolamines, compositions containing the same, and method for effecting weight control
IL57673A0 (en) * 1978-07-03 1979-10-31 Lilly Co Eli Optically active phenethanolamines and method for increasing cardiac contractility
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions
ATE1994T1 (de) * 1979-06-16 1982-12-15 Beecham Group Plc Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
DE3062216D1 (en) * 1979-09-06 1983-04-07 Beecham Group Plc Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them
EP0028105B1 (en) * 1979-10-25 1983-01-19 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions
ATE14222T1 (de) * 1979-11-15 1985-07-15 Beecham Group Plc Sekundaere aethanolamine, ihre herstellung und ihre verwendung in pharmazeutischen zusammensetzungen.
EP0040000B1 (en) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
EP0040915B1 (en) * 1980-05-22 1984-03-21 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
GB2084577B (en) * 1980-09-26 1984-05-02 Beecham Group Ltd Secondary amines
EP0066351B1 (en) * 1981-03-06 1985-06-26 Beecham Group Plc Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions
DE3260490D1 (en) * 1981-03-31 1984-09-06 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
EP0063004A1 (en) * 1981-04-09 1982-10-20 Beecham Group Plc Secondary amines, processes for their preparation, and pharmaceutical compositions containing them
EP0068669A1 (en) * 1981-06-20 1983-01-05 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0070133B1 (en) * 1981-07-11 1986-05-14 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0070134B1 (en) * 1981-07-11 1985-11-13 Beecham Group Plc Secondary phenyl ethanol amines and their pharmaceutical use
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines

Also Published As

Publication number Publication date
IE55896B1 (en) 1991-02-14
US4585796A (en) 1986-04-29
HU191867B (en) 1987-04-28
PT77173B (en) 1986-03-20
CS586083A2 (en) 1985-06-13
IL69438A0 (en) 1983-11-30
AU1758883A (en) 1984-02-16
PT77173A (en) 1983-09-01
FI832844A0 (fi) 1983-08-08
ZW15483A1 (en) 1985-01-30
DK350083D0 (da) 1983-07-29
IE831872L (en) 1984-02-10
IL69438A (en) 1986-08-31
EP0101069B1 (de) 1986-04-23
EP0101069A1 (de) 1984-02-22
CS240972B2 (en) 1986-03-13
DE3363177D1 (de) 1986-05-28
ES524823A0 (es) 1985-06-01
FI80030C (fi) 1990-04-10
ES8505333A1 (es) 1985-06-01
NO832867L (no) 1984-02-13
CA1258454A (en) 1989-08-15
MC1536A1 (fr) 1984-05-25
DK350083A (da) 1984-02-11
AU570640B2 (en) 1988-03-24
NZ205132A (en) 1987-03-06
FI80030B (fi) 1989-12-29
PH18647A (en) 1985-08-23

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG