CS240972B2 - Production method of new phenethanolamines - Google Patents
Production method of new phenethanolamines Download PDFInfo
- Publication number
- CS240972B2 CS240972B2 CS835860A CS586083A CS240972B2 CS 240972 B2 CS240972 B2 CS 240972B2 CS 835860 A CS835860 A CS 835860A CS 586083 A CS586083 A CS 586083A CS 240972 B2 CS240972 B2 CS 240972B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- group
- amino
- methyl
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Battery Electrode And Active Subsutance (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH478782 | 1982-08-10 | ||
| CH289783 | 1983-05-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS586083A2 CS586083A2 (en) | 1985-06-13 |
| CS240972B2 true CS240972B2 (en) | 1986-03-13 |
Family
ID=25691672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS835860A CS240972B2 (en) | 1982-08-10 | 1983-08-09 | Production method of new phenethanolamines |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4585796A (da) |
| EP (1) | EP0101069B1 (da) |
| AU (1) | AU570640B2 (da) |
| CA (1) | CA1258454A (da) |
| CS (1) | CS240972B2 (da) |
| DE (1) | DE3363177D1 (da) |
| DK (1) | DK350083A (da) |
| ES (1) | ES524823A0 (da) |
| FI (1) | FI80030C (da) |
| HU (1) | HU191867B (da) |
| IE (1) | IE55896B1 (da) |
| IL (1) | IL69438A (da) |
| MC (1) | MC1536A1 (da) |
| NO (1) | NO832867L (da) |
| NZ (1) | NZ205132A (da) |
| PH (1) | PH18647A (da) |
| PT (1) | PT77173B (da) |
| ZW (1) | ZW15483A1 (da) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
| US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
| CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
| GB8415377D0 (en) * | 1984-06-15 | 1984-07-18 | Beecham Group Plc | Compounds |
| GB8418472D0 (en) * | 1984-07-19 | 1984-08-22 | Beecham Group Plc | Compounds |
| PT82120B (en) * | 1985-03-01 | 1988-06-16 | Beecham Group Plc | Process for preparing veterinary formulations containing ethanolamine derivatives |
| NZ215753A (en) * | 1985-04-16 | 1989-10-27 | Hoffmann La Roche | Phenethanolamine derivatives and pharmaceutical compositions |
| CA1287061C (en) * | 1986-06-27 | 1991-07-30 | Roche Holding Ltd. | Pyridine ethanolamine derivatives |
| DE3718638A1 (de) * | 1987-06-04 | 1988-12-22 | Thomae Gmbh Dr K | Neue phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| FI892341L (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
| US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
| US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
| US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| EP1296142B1 (en) * | 1991-08-23 | 2005-12-07 | Nps Pharmaceuticals, Inc. | Screening method for calcium receptor active molecules |
| US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
| US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
| US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
| NZ297157A (en) | 1994-10-21 | 1999-08-30 | Nps Pharma Inc | Amine derivatives with calcium ion receptor activity; medicaments containing such compounds |
| AU731146C (en) | 1996-05-01 | 2005-02-03 | Nps Pharmaceuticals, Inc. | Inorganic ion receptor-active compounds |
| CA2551037A1 (en) | 2003-09-22 | 2005-03-31 | Banyu Pharmaceutical Co., Ltd. | Novel piperidine derivative |
| US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
| EP2330125A3 (en) | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| AU2006279680B2 (en) | 2005-08-11 | 2012-12-06 | Amylin Pharmaceuticals, Llc | Hybrid polypeptides with selectable properties |
| US20080255084A1 (en) | 2005-10-21 | 2008-10-16 | Randy Lee Webb | Combination of Organic Compounds |
| EP2083831B1 (en) | 2006-09-22 | 2013-12-25 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
| WO2009154132A1 (ja) | 2008-06-19 | 2009-12-23 | 萬有製薬株式会社 | スピロジアミン-ジアリールケトオキシム誘導体 |
| CN102272103B (zh) | 2008-10-30 | 2015-10-21 | 默沙东公司 | 异烟酰胺食欲素受体拮抗剂 |
| EP2379547A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
| WO2010075069A1 (en) | 2008-12-16 | 2010-07-01 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| AR088352A1 (es) | 2011-10-19 | 2014-05-28 | Merck Sharp & Dohme | Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina |
| WO2014022528A1 (en) | 2012-08-02 | 2014-02-06 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| JP7664850B2 (ja) | 2019-04-29 | 2025-04-18 | エコラボ ユーエスエー インコーポレイティド | 酸素化アミノフェノール化合物およびモノマー重合を防止するための方法 |
| WO2020223225A1 (en) | 2019-04-29 | 2020-11-05 | Ecolab Usa Inc. | Oxygenated aromatic amines and use as antioxidants |
| EP4232489A1 (en) | 2020-10-21 | 2023-08-30 | Ecolab USA Inc. | (hydroxyalkyl)aminophenol polymers and methods of use |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD45721A (da) * | ||||
| GB1109924A (en) * | 1965-11-29 | 1968-04-18 | Roche Products Ltd | Novel substituted diphenylalkyl amines and a process for the manufacture thereof |
| GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
| US3732300A (en) * | 1966-09-23 | 1973-05-08 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
| US4101579A (en) * | 1969-02-06 | 1978-07-18 | Allen & Hanburys Limited | Phenethanolamine ethers |
| DE1922003C3 (de) * | 1969-04-30 | 1979-10-11 | Boehringer Mannheim Gmbh, 6800 Mannheim | N-(3-Aryloxy-2-hydroxypropyl)-aminocarbonsäuren, deren Ester, Amide und Salze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung von Herzinsuffizienz |
| DE2023829C3 (de) * | 1970-05-15 | 1979-06-21 | Pfizer Corp., Colon (Panama) | Kernsubstituierte 3-Phenoxy-lphenoxyalkyl-amino-propan-2-oIe, Verfahren zu ihrer Herstellung sowie Arzneimittel |
| US3867455A (en) * | 1970-06-02 | 1975-02-18 | Allen & Hanburys Ltd | Preparation of phenylaminoethanols |
| US4137328A (en) * | 1970-07-18 | 1979-01-30 | Pfizer Inc. | Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants |
| GB1394001A (en) * | 1972-12-22 | 1975-05-14 | Pfizer Ltd | 2-morpholino or homomorpholino 1-3-trifluoromethylphenyl propanes |
| IL57671A (en) * | 1978-07-03 | 1982-11-30 | Lilly Co Eli | Phenethanolamines,process for their preparation and pharmaceutical and animal feed compositions containing the same |
| IL57670A (en) * | 1978-07-03 | 1982-11-30 | Lilly Co Eli | Phenethanolamines,their preparation and pharmaceutical formulations comprising them |
| DK269079A (da) * | 1978-07-03 | 1980-02-01 | Lilly Co Eli | Fremgangsmaade til fremstilling af phenethanolaminer |
| US4338333A (en) * | 1979-06-16 | 1982-07-06 | Beecham Group Limited | Ethanamine derivatives their preparation and use in pharmaceutical compositions |
| DE3061205D1 (en) * | 1979-06-16 | 1983-01-05 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
| DE3062216D1 (en) * | 1979-09-06 | 1983-04-07 | Beecham Group Plc | Cinnamic acid derivatives, their preparation, and pharmaceutical compositions containing them |
| EP0028105B1 (en) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
| EP0029320B1 (en) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions |
| DE3161165D1 (en) * | 1980-05-08 | 1983-11-17 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
| EP0040915B1 (en) * | 1980-05-22 | 1984-03-21 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
| GB2084577B (en) * | 1980-09-26 | 1984-05-02 | Beecham Group Ltd | Secondary amines |
| EP0066351B1 (en) * | 1981-03-06 | 1985-06-26 | Beecham Group Plc | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions |
| EP0061907B1 (en) * | 1981-03-31 | 1984-08-01 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| EP0063004A1 (en) * | 1981-04-09 | 1982-10-20 | Beecham Group Plc | Secondary amines, processes for their preparation, and pharmaceutical compositions containing them |
| EP0068669A1 (en) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
| DE3267406D1 (en) * | 1981-07-11 | 1985-12-19 | Beecham Group Plc | Secondary phenyl ethanol amines and their pharmaceutical use |
| EP0070133B1 (en) * | 1981-07-11 | 1986-05-14 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
| CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
-
1983
- 1983-07-04 CA CA000431762A patent/CA1258454A/en not_active Expired
- 1983-07-06 ZW ZW154/83A patent/ZW15483A1/xx unknown
- 1983-07-29 DK DK350083A patent/DK350083A/da not_active Application Discontinuation
- 1983-08-01 US US06/518,990 patent/US4585796A/en not_active Expired - Fee Related
- 1983-08-03 NZ NZ205132A patent/NZ205132A/en unknown
- 1983-08-04 AU AU17588/83A patent/AU570640B2/en not_active Ceased
- 1983-08-04 IL IL69438A patent/IL69438A/xx unknown
- 1983-08-08 HU HU832789A patent/HU191867B/hu not_active IP Right Cessation
- 1983-08-08 FI FI832844A patent/FI80030C/fi not_active IP Right Cessation
- 1983-08-09 IE IE1872/83A patent/IE55896B1/en not_active IP Right Cessation
- 1983-08-09 PH PH29376A patent/PH18647A/en unknown
- 1983-08-09 MC MC831652A patent/MC1536A1/fr unknown
- 1983-08-09 ES ES524823A patent/ES524823A0/es active Granted
- 1983-08-09 PT PT77173A patent/PT77173B/pt not_active IP Right Cessation
- 1983-08-09 CS CS835860A patent/CS240972B2/cs unknown
- 1983-08-09 NO NO832867A patent/NO832867L/no unknown
- 1983-08-10 EP EP83107908A patent/EP0101069B1/de not_active Expired
- 1983-08-10 DE DE8383107908T patent/DE3363177D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU570640B2 (en) | 1988-03-24 |
| CA1258454A (en) | 1989-08-15 |
| US4585796A (en) | 1986-04-29 |
| IL69438A (en) | 1986-08-31 |
| PT77173A (en) | 1983-09-01 |
| EP0101069A1 (de) | 1984-02-22 |
| ZW15483A1 (en) | 1985-01-30 |
| DK350083A (da) | 1984-02-11 |
| FI832844A7 (fi) | 1984-02-11 |
| MC1536A1 (fr) | 1984-05-25 |
| FI80030C (fi) | 1990-04-10 |
| DK350083D0 (da) | 1983-07-29 |
| AU1758883A (en) | 1984-02-16 |
| EP0101069B1 (de) | 1986-04-23 |
| ES8505333A1 (es) | 1985-06-01 |
| CS586083A2 (en) | 1985-06-13 |
| PT77173B (en) | 1986-03-20 |
| NZ205132A (en) | 1987-03-06 |
| FI832844A0 (fi) | 1983-08-08 |
| PH18647A (en) | 1985-08-23 |
| ES524823A0 (es) | 1985-06-01 |
| IE831872L (en) | 1984-02-10 |
| IL69438A0 (en) | 1983-11-30 |
| IE55896B1 (en) | 1991-02-14 |
| FI80030B (fi) | 1989-12-29 |
| DE3363177D1 (de) | 1986-05-28 |
| HU191867B (en) | 1987-04-28 |
| NO832867L (no) | 1984-02-13 |
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