CS239930B2 - Pharmceutical holder - Google Patents
Pharmceutical holder Download PDFInfo
- Publication number
- CS239930B2 CS239930B2 CS826268A CS626882A CS239930B2 CS 239930 B2 CS239930 B2 CS 239930B2 CS 826268 A CS826268 A CS 826268A CS 626882 A CS626882 A CS 626882A CS 239930 B2 CS239930 B2 CS 239930B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- asa
- water
- milk
- potassium phosphate
- pharmaceutical carrier
- Prior art date
Links
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims abstract description 40
- 239000000203 mixture Substances 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 28
- 235000013336 milk Nutrition 0.000 claims abstract description 26
- 239000008267 milk Substances 0.000 claims abstract description 26
- 210000004080 milk Anatomy 0.000 claims abstract description 26
- 239000007787 solid Substances 0.000 claims abstract description 25
- 239000003937 drug carrier Substances 0.000 claims abstract description 9
- 230000002378 acidificating effect Effects 0.000 claims abstract description 6
- 229910000160 potassium phosphate Inorganic materials 0.000 claims description 18
- 235000011009 potassium phosphates Nutrition 0.000 claims description 18
- 239000000843 powder Substances 0.000 claims description 16
- 235000020183 skimmed milk Nutrition 0.000 claims description 14
- 235000003599 food sweetener Nutrition 0.000 claims description 7
- 239000003765 sweetening agent Substances 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 6
- 239000003086 colorant Substances 0.000 claims description 4
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 claims description 3
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000013355 food flavoring agent Nutrition 0.000 claims description 2
- 239000013543 active substance Substances 0.000 claims 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract description 33
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract description 33
- 239000004480 active ingredient Substances 0.000 abstract description 11
- 239000007788 liquid Substances 0.000 abstract description 5
- 239000000546 pharmaceutical excipient Substances 0.000 abstract description 2
- 238000013329 compounding Methods 0.000 abstract 1
- 229910000404 tripotassium phosphate Inorganic materials 0.000 abstract 1
- 235000019798 tripotassium phosphate Nutrition 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000008194 pharmaceutical composition Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- -1 for example Substances 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 150000004682 monohydrates Chemical class 0.000 description 2
- 230000003472 neutralizing effect Effects 0.000 description 2
- ILJOYZVVZZFIKA-UHFFFAOYSA-M sodium;1,1-dioxo-1,2-benzothiazol-3-olate;hydrate Chemical compound O.[Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 ILJOYZVVZZFIKA-UHFFFAOYSA-M 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010053155 Epigastric discomfort Diseases 0.000 description 1
- 206010022653 Intestinal haemorrhages Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- IOYNQIMAUDJVEI-BMVIKAAMSA-N Tepraloxydim Chemical group C1C(=O)C(C(=N/OC\C=C\Cl)/CC)=C(O)CC1C1CCOCC1 IOYNQIMAUDJVEI-BMVIKAAMSA-N 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- JAWMENYCRQKKJY-UHFFFAOYSA-N [3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-ylmethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]methanone Chemical compound N1N=NC=2CN(CCC=21)CC1=NOC2(C1)CCN(CC2)C(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F JAWMENYCRQKKJY-UHFFFAOYSA-N 0.000 description 1
- 206010000059 abdominal discomfort Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229920002877 acrylic styrene acrylonitrile Polymers 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 229960004909 aminosalicylic acid Drugs 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000008366 buffered solution Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 208000016354 hearing loss disease Diseases 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- GTTYPHLDORACJW-UHFFFAOYSA-N nitric acid;sodium Chemical compound [Na].O[N+]([O-])=O GTTYPHLDORACJW-UHFFFAOYSA-N 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000012254 powdered material Substances 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
- 229960001860 salicylate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000008371 vanilla flavor Substances 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pens And Brushes (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Prostheses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Dairy Products (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP81106715A EP0073259B1 (de) | 1981-08-28 | 1981-08-28 | Pharmazeutische Grundmasse und Präparate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS626882A2 CS626882A2 (en) | 1984-12-14 |
| CS239930B2 true CS239930B2 (en) | 1986-01-16 |
Family
ID=8187875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS826268A CS239930B2 (en) | 1981-08-28 | 1982-08-27 | Pharmceutical holder |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4399128A (de) |
| EP (1) | EP0073259B1 (de) |
| JP (1) | JPS5846014A (de) |
| KR (1) | KR830007075A (de) |
| AT (1) | ATE15329T1 (de) |
| AU (1) | AU548220B2 (de) |
| CA (1) | CA1200493A (de) |
| CS (1) | CS239930B2 (de) |
| DD (1) | DD203465A5 (de) |
| DE (1) | DE3172139D1 (de) |
| DK (2) | DK161364C (de) |
| EG (1) | EG17413A (de) |
| ES (1) | ES8404185A1 (de) |
| FI (1) | FI77779C (de) |
| GB (1) | GB2104778B (de) |
| GR (1) | GR77596B (de) |
| HK (1) | HK50085A (de) |
| IE (1) | IE53830B1 (de) |
| IL (1) | IL66095A0 (de) |
| KE (1) | KE3488A (de) |
| MA (1) | MA19577A1 (de) |
| NO (1) | NO157685C (de) |
| NZ (1) | NZ201080A (de) |
| PH (1) | PH18880A (de) |
| PT (1) | PT75335B (de) |
| SG (1) | SG86484G (de) |
| ZA (1) | ZA824603B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61110144A (ja) * | 1984-11-05 | 1986-05-28 | Daicel Chem Ind Ltd | 静電記録体 |
| GB2261372A (en) * | 1991-11-15 | 1993-05-19 | Gregor Reid | Lactobacillus and skim milk compositions for prevention of urogenital infection |
| US6708822B1 (en) | 1999-11-30 | 2004-03-23 | Cutispharma, Inc. | Compositions and kits for compounding pharmaceuticals |
| US20040191276A1 (en) * | 1999-11-30 | 2004-09-30 | Cutispharma, Inc. | Compositions and kits for compounding pharmaceuticals |
| US7623250B2 (en) | 2005-02-04 | 2009-11-24 | Stryker Leibinger Gmbh & Co. Kg. | Enhanced shape characterization device and method |
| CA2961699C (en) | 2014-09-23 | 2022-10-11 | Jost Chemical Co. | Fatty acid composition and method for fortifying nutritional products with fatty acids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB754364A (en) * | 1953-10-09 | 1956-08-08 | Drug Houses Of Australia Ltd | Improvements in medicinal preparations containing acetylsalicylic acid |
| US3608064A (en) * | 1969-10-07 | 1971-09-21 | Anthony H Lamb | Milk-buffered aspirin |
| IL44774A (en) * | 1974-05-06 | 1977-07-31 | Baron E | Pharmaceutical composition containing acetyl salicyclic acid |
-
1981
- 1981-08-28 AT AT81106715T patent/ATE15329T1/de not_active IP Right Cessation
- 1981-08-28 EP EP81106715A patent/EP0073259B1/de not_active Expired
- 1981-08-28 DE DE8181106715T patent/DE3172139D1/de not_active Expired
- 1981-11-23 GB GB08135244A patent/GB2104778B/en not_active Expired
- 1981-11-25 KR KR1019810004559A patent/KR830007075A/ko not_active Ceased
-
1982
- 1982-06-22 AU AU85094/82A patent/AU548220B2/en not_active Ceased
- 1982-06-22 IL IL66095A patent/IL66095A0/xx not_active IP Right Cessation
- 1982-06-25 NZ NZ201080A patent/NZ201080A/en unknown
- 1982-06-28 ZA ZA824603A patent/ZA824603B/xx unknown
- 1982-06-29 US US06/393,507 patent/US4399128A/en not_active Expired - Lifetime
- 1982-07-06 CA CA000406701A patent/CA1200493A/en not_active Expired
- 1982-07-19 NO NO822488A patent/NO157685C/no unknown
- 1982-07-27 PT PT75335A patent/PT75335B/pt not_active IP Right Cessation
- 1982-08-13 PH PH27728A patent/PH18880A/en unknown
- 1982-08-24 FI FI822927A patent/FI77779C/fi not_active IP Right Cessation
- 1982-08-24 MA MA19789A patent/MA19577A1/fr unknown
- 1982-08-25 GR GR69104A patent/GR77596B/el unknown
- 1982-08-25 EG EG517/82A patent/EG17413A/xx active
- 1982-08-25 DD DD82242797A patent/DD203465A5/de unknown
- 1982-08-26 DK DK382482A patent/DK161364C/da not_active IP Right Cessation
- 1982-08-27 IE IE2076/82A patent/IE53830B1/en not_active IP Right Cessation
- 1982-08-27 ES ES515300A patent/ES8404185A1/es not_active Expired
- 1982-08-27 CS CS826268A patent/CS239930B2/cs unknown
- 1982-08-27 JP JP57149034A patent/JPS5846014A/ja active Granted
-
1984
- 1984-12-04 SG SG864/84A patent/SG86484G/en unknown
- 1984-12-07 KE KE3488A patent/KE3488A/xx unknown
-
1985
- 1985-06-27 HK HK500/85A patent/HK50085A/xx unknown
-
1991
- 1991-02-19 DK DK028091A patent/DK163281C/da active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1275933C (en) | Therapeutic composition containing ibuprofen | |
| US3567819A (en) | Cold tablet | |
| US4093710A (en) | Rapid dissolving effervescent granules | |
| ES2283038T3 (es) | Granulado instantaneo de calcio y soja. | |
| US5102665A (en) | Pharmaceutical compositions | |
| KR100573421B1 (ko) | 비타민 ｄ 및 칼슘을 포함하는 약학적 조성물, 그제조방법 및 치료적 용도 | |
| CS239930B2 (en) | Pharmceutical holder | |
| US5728401A (en) | Effervescent ranitidine formulations | |
| JP2002525092A (ja) | 栄養および薬剤組成物 | |
| EP0719148B1 (de) | Asserlösliche pharmazeutische zusammensetzungen, die östronderivate und kalziumsalze enthalten | |
| JPH02292220A (ja) | 薬剤組成物 | |
| ES2252078T3 (es) | Composicion efervescente de antagonista h2 de histamina. | |
| NO173125B (no) | Farmasoeytisk baerer for anvendelse sammen med acetylsalisylsyre | |
| HK1027751B (en) | Pharmaceutical compositions containing vitamin d and calcium, their preparation and therapeutic use | |
| MXPA99008920A (en) | Antacid and papain combination |