CS236900B2 - Processing of 6alpha-methylprednisolon derivatives - Google Patents

Processing of 6alpha-methylprednisolon derivatives Download PDF

Info

Publication number
CS236900B2
CS236900B2 CS839879A CS987983A CS236900B2 CS 236900 B2 CS236900 B2 CS 236900B2 CS 839879 A CS839879 A CS 839879A CS 987983 A CS987983 A CS 987983A CS 236900 B2 CS236900 B2 CS 236900B2
Authority
CS
Czechoslovakia
Prior art keywords
dione
methyl
pregnadien
bromo
derivatives
Prior art date
Application number
CS839879A
Other languages
Czech (cs)
English (en)
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS236900B2 publication Critical patent/CS236900B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS839879A 1982-12-23 1983-12-23 Processing of 6alpha-methylprednisolon derivatives CS236900B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823248435 DE3248435A1 (de) 1982-12-23 1982-12-23 Neue 6(alpha)-methylprednisolon-derivate ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
CS236900B2 true CS236900B2 (en) 1985-05-15

Family

ID=6182025

Family Applications (1)

Application Number Title Priority Date Filing Date
CS839879A CS236900B2 (en) 1982-12-23 1983-12-23 Processing of 6alpha-methylprednisolon derivatives

Country Status (21)

Country Link
EP (1) EP0112467B1 (enrdf_load_stackoverflow)
JP (1) JPS59130300A (enrdf_load_stackoverflow)
AT (1) ATE28878T1 (enrdf_load_stackoverflow)
AU (1) AU2220283A (enrdf_load_stackoverflow)
CA (1) CA1250571A (enrdf_load_stackoverflow)
CS (1) CS236900B2 (enrdf_load_stackoverflow)
DD (1) DD210694A5 (enrdf_load_stackoverflow)
DE (2) DE3248435A1 (enrdf_load_stackoverflow)
DK (1) DK159118C (enrdf_load_stackoverflow)
ES (1) ES528323A0 (enrdf_load_stackoverflow)
GB (1) GB2132620B (enrdf_load_stackoverflow)
GR (1) GR79453B (enrdf_load_stackoverflow)
HU (1) HU187939B (enrdf_load_stackoverflow)
IE (1) IE56400B1 (enrdf_load_stackoverflow)
IL (1) IL70452A (enrdf_load_stackoverflow)
NO (1) NO156410C (enrdf_load_stackoverflow)
PL (1) PL141513B1 (enrdf_load_stackoverflow)
PT (1) PT77880B (enrdf_load_stackoverflow)
RO (1) RO88666A (enrdf_load_stackoverflow)
SU (1) SU1299514A3 (enrdf_load_stackoverflow)
ZA (1) ZA839573B (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19644679C2 (de) * 1996-10-28 1999-06-02 Freudenberg Carl Fa Wischbezug

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
DE2645104C2 (de) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
GB2132620A (en) 1984-07-11
NO156410B (no) 1987-06-09
DD210694A5 (de) 1984-06-20
IL70452A0 (en) 1984-03-30
ATE28878T1 (de) 1987-08-15
GB2132620B (en) 1986-06-04
SU1299514A3 (ru) 1987-03-23
DE3248435A1 (de) 1984-06-28
AU2220283A (en) 1984-06-28
EP0112467A1 (de) 1984-07-04
GR79453B (enrdf_load_stackoverflow) 1984-10-30
ZA839573B (en) 1984-08-29
PL245246A1 (en) 1984-10-22
ES8502128A1 (es) 1985-01-01
DK597783A (da) 1984-06-24
NO156410C (no) 1987-09-30
IL70452A (en) 1987-12-31
PT77880B (de) 1986-04-09
DK159118B (da) 1990-09-03
ES528323A0 (es) 1985-01-01
DE3372970D1 (en) 1987-09-17
JPH0415800B2 (enrdf_load_stackoverflow) 1992-03-19
DK597783D0 (da) 1983-12-23
PL141513B1 (en) 1987-08-31
DK159118C (da) 1991-02-11
PT77880A (de) 1984-01-01
JPS59130300A (ja) 1984-07-26
RO88666A (ro) 1986-02-28
EP0112467B1 (de) 1987-08-12
HU187939B (en) 1986-03-28
NO834759L (no) 1984-06-25
GB8333741D0 (en) 1984-01-25
IE56400B1 (en) 1991-07-17
CA1250571A (en) 1989-02-28
IE832944L (en) 1984-06-23

Similar Documents

Publication Publication Date Title
EP0072547B1 (de) Neue 6-alpha-Methylprednisolon-Derivate ihre Herstellung und Verwendung
US5972922A (en) Steroids which inhibit angiogenesis
US4555507A (en) Novel 6, 16-dimethylcorticoids, their preparation and use
US4645763A (en) 6α-methyl corticoids, their production and use
JPH033679B2 (enrdf_load_stackoverflow)
US4777165A (en) 6α, 16β-dimethyl corticoids and their anti-inflammatory use
CS231197B2 (en) Processing method of derivative of 6alpha-methylhydrokortisone
CA1251784A (en) Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments
CS236900B2 (en) Processing of 6alpha-methylprednisolon derivatives
US4619922A (en) 6α, 16α-dimethyl corticoids
CA1104124A (en) Derivatives of 9-fluoroprednisolone
JPS6129960B2 (enrdf_load_stackoverflow)
CS248729B2 (cs) Způsob výroby derivátů 6a-niethylkortikoidu
CS244663B2 (cs) Způsob výroby nových derivátů 9-chlorprednisolonu
CS244147B2 (cs) Způsob výroby 6<x--methylprednisolonových derivátů
CS244662B2 (cs) Způsob výroby nových derivátů 9-chlorprednisolonu
CS207758B2 (cs) Způsob výroby v poloze pregnanové řady 17 substituovaných 11/3-hydroxysteroidů
CS199512B2 (cs) Způsob výroby kortikoidfi
DE2809732A1 (de) Neue derivate des 9-fluorprednisolons