IL70452A - 6alpha-methylprednisolone derivatives,process for the manufacture thereof and pharmaceutical compositions containing the same - Google Patents

6alpha-methylprednisolone derivatives,process for the manufacture thereof and pharmaceutical compositions containing the same

Info

Publication number
IL70452A
IL70452A IL70452A IL7045283A IL70452A IL 70452 A IL70452 A IL 70452A IL 70452 A IL70452 A IL 70452A IL 7045283 A IL7045283 A IL 7045283A IL 70452 A IL70452 A IL 70452A
Authority
IL
Israel
Prior art keywords
manufacture
6alpha
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL70452A
Other versions
IL70452A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL70452A0 publication Critical patent/IL70452A0/en
Publication of IL70452A publication Critical patent/IL70452A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Abstract

Novel 6 alpha -methylprednisolone derivatives of the general formula I <IMAGE> (in which R1 represents C2-C6-I-oxoalkyl or benzoyl and R2 represents H, C2-C6- I-oxoalkyl or benzoyl) and a process for their manufacture. The novel compounds are useful in the treatment of skin disorders and of allergic disorders of the respiratory and intestinal tracts.
IL70452A 1982-12-23 1983-12-15 6alpha-methylprednisolone derivatives,process for the manufacture thereof and pharmaceutical compositions containing the same IL70452A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823248435 DE3248435A1 (en) 1982-12-23 1982-12-23 NEW 6 (ALPHA) METHYLPREDNISOLONE DERIVATIVES THEIR PRODUCTION AND USE

Publications (2)

Publication Number Publication Date
IL70452A0 IL70452A0 (en) 1984-03-30
IL70452A true IL70452A (en) 1987-12-31

Family

ID=6182025

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70452A IL70452A (en) 1982-12-23 1983-12-15 6alpha-methylprednisolone derivatives,process for the manufacture thereof and pharmaceutical compositions containing the same

Country Status (21)

Country Link
EP (1) EP0112467B1 (en)
JP (1) JPS59130300A (en)
AT (1) ATE28878T1 (en)
AU (1) AU2220283A (en)
CA (1) CA1250571A (en)
CS (1) CS236900B2 (en)
DD (1) DD210694A5 (en)
DE (2) DE3248435A1 (en)
DK (1) DK159118C (en)
ES (1) ES8502128A1 (en)
GB (1) GB2132620B (en)
GR (1) GR79453B (en)
HU (1) HU187939B (en)
IE (1) IE56400B1 (en)
IL (1) IL70452A (en)
NO (1) NO156410C (en)
PL (1) PL141513B1 (en)
PT (1) PT77880B (en)
RO (1) RO88666A (en)
SU (1) SU1299514A3 (en)
ZA (1) ZA839573B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19644679C2 (en) * 1996-10-28 1999-06-02 Freudenberg Carl Fa Mop cover

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
DE2645104C2 (en) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatriene-3,20-dione derivatives and processes for their preparation

Also Published As

Publication number Publication date
EP0112467A1 (en) 1984-07-04
DK159118C (en) 1991-02-11
JPS59130300A (en) 1984-07-26
DK597783D0 (en) 1983-12-23
PT77880B (en) 1986-04-09
DE3248435A1 (en) 1984-06-28
AU2220283A (en) 1984-06-28
CA1250571A (en) 1989-02-28
NO156410C (en) 1987-09-30
IL70452A0 (en) 1984-03-30
HU187939B (en) 1986-03-28
GB8333741D0 (en) 1984-01-25
ES528323A0 (en) 1985-01-01
PL141513B1 (en) 1987-08-31
IE832944L (en) 1984-06-23
ES8502128A1 (en) 1985-01-01
GB2132620B (en) 1986-06-04
NO834759L (en) 1984-06-25
GB2132620A (en) 1984-07-11
EP0112467B1 (en) 1987-08-12
PT77880A (en) 1984-01-01
DE3372970D1 (en) 1987-09-17
DD210694A5 (en) 1984-06-20
DK597783A (en) 1984-06-24
GR79453B (en) 1984-10-30
ATE28878T1 (en) 1987-08-15
PL245246A1 (en) 1984-10-22
ZA839573B (en) 1984-08-29
CS236900B2 (en) 1985-05-15
RO88666A (en) 1986-02-28
JPH0415800B2 (en) 1992-03-19
NO156410B (en) 1987-06-09
IE56400B1 (en) 1991-07-17
SU1299514A3 (en) 1987-03-23
DK159118B (en) 1990-09-03

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees