DK597783D0 - 6ALFA METHYLPREDNISOLON DERIVATIVES AND THE PREPARATION AND APPLICATION OF THEREOF - Google Patents

6ALFA METHYLPREDNISOLON DERIVATIVES AND THE PREPARATION AND APPLICATION OF THEREOF

Info

Publication number
DK597783D0
DK597783D0 DK5977/83A DK597783A DK597783D0 DK 597783 D0 DK597783 D0 DK 597783D0 DK 5977/83 A DK5977/83 A DK 5977/83A DK 597783 A DK597783 A DK 597783A DK 597783 D0 DK597783 D0 DK 597783D0
Authority
DK
Denmark
Prior art keywords
derivatives
6alfa
methylprednisolon
preparation
application
Prior art date
Application number
DK5977/83A
Other languages
Danish (da)
Other versions
DK159118C (en
DK159118B (en
DK597783A (en
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK597783D0 publication Critical patent/DK597783D0/en
Publication of DK597783A publication Critical patent/DK597783A/en
Publication of DK159118B publication Critical patent/DK159118B/en
Application granted granted Critical
Publication of DK159118C publication Critical patent/DK159118C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Novel 6 alpha -methylprednisolone derivatives of the general formula I <IMAGE> (in which R1 represents C2-C6-I-oxoalkyl or benzoyl and R2 represents H, C2-C6- I-oxoalkyl or benzoyl) and a process for their manufacture. The novel compounds are useful in the treatment of skin disorders and of allergic disorders of the respiratory and intestinal tracts.
DK597783A 1982-12-23 1983-12-23 6ALFA METHYLPREDNISOLON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM DK159118C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823248435 DE3248435A1 (en) 1982-12-23 1982-12-23 NEW 6 (ALPHA) METHYLPREDNISOLONE DERIVATIVES THEIR PRODUCTION AND USE
DE3248435 1982-12-23

Publications (4)

Publication Number Publication Date
DK597783D0 true DK597783D0 (en) 1983-12-23
DK597783A DK597783A (en) 1984-06-24
DK159118B DK159118B (en) 1990-09-03
DK159118C DK159118C (en) 1991-02-11

Family

ID=6182025

Family Applications (1)

Application Number Title Priority Date Filing Date
DK597783A DK159118C (en) 1982-12-23 1983-12-23 6ALFA METHYLPREDNISOLON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Country Status (21)

Country Link
EP (1) EP0112467B1 (en)
JP (1) JPS59130300A (en)
AT (1) ATE28878T1 (en)
AU (1) AU2220283A (en)
CA (1) CA1250571A (en)
CS (1) CS236900B2 (en)
DD (1) DD210694A5 (en)
DE (2) DE3248435A1 (en)
DK (1) DK159118C (en)
ES (1) ES528323A0 (en)
GB (1) GB2132620B (en)
GR (1) GR79453B (en)
HU (1) HU187939B (en)
IE (1) IE56400B1 (en)
IL (1) IL70452A (en)
NO (1) NO156410C (en)
PL (1) PL141513B1 (en)
PT (1) PT77880B (en)
RO (1) RO88666A (en)
SU (1) SU1299514A3 (en)
ZA (1) ZA839573B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19644679C2 (en) * 1996-10-28 1999-06-02 Freudenberg Carl Fa Mop cover

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
DE2645104C2 (en) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatriene-3,20-dione derivatives and processes for their preparation

Also Published As

Publication number Publication date
PL245246A1 (en) 1984-10-22
EP0112467B1 (en) 1987-08-12
PL141513B1 (en) 1987-08-31
JPS59130300A (en) 1984-07-26
CA1250571A (en) 1989-02-28
DE3372970D1 (en) 1987-09-17
RO88666A (en) 1986-02-28
JPH0415800B2 (en) 1992-03-19
ES8502128A1 (en) 1985-01-01
PT77880A (en) 1984-01-01
ZA839573B (en) 1984-08-29
PT77880B (en) 1986-04-09
NO156410C (en) 1987-09-30
GR79453B (en) 1984-10-30
IL70452A (en) 1987-12-31
CS236900B2 (en) 1985-05-15
HU187939B (en) 1986-03-28
IL70452A0 (en) 1984-03-30
NO156410B (en) 1987-06-09
AU2220283A (en) 1984-06-28
SU1299514A3 (en) 1987-03-23
GB2132620A (en) 1984-07-11
GB8333741D0 (en) 1984-01-25
ATE28878T1 (en) 1987-08-15
DK159118C (en) 1991-02-11
DK159118B (en) 1990-09-03
EP0112467A1 (en) 1984-07-04
IE832944L (en) 1984-06-23
DE3248435A1 (en) 1984-06-28
IE56400B1 (en) 1991-07-17
ES528323A0 (en) 1985-01-01
DK597783A (en) 1984-06-24
DD210694A5 (en) 1984-06-20
GB2132620B (en) 1986-06-04
NO834759L (en) 1984-06-25

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Legal Events

Date Code Title Description
PBP Patent lapsed