NO834759L - PROCEDURE FOR THE PREPARATION OF NEW 6ALFA METHYLPREDNISOLON DERIVATIVES - Google Patents

PROCEDURE FOR THE PREPARATION OF NEW 6ALFA METHYLPREDNISOLON DERIVATIVES

Info

Publication number
NO834759L
NO834759L NO834759A NO834759A NO834759L NO 834759 L NO834759 L NO 834759L NO 834759 A NO834759 A NO 834759A NO 834759 A NO834759 A NO 834759A NO 834759 L NO834759 L NO 834759L
Authority
NO
Norway
Prior art keywords
derivatives
6alfa
methylprednisolon
procedure
preparation
Prior art date
Application number
NO834759A
Other languages
Norwegian (no)
Other versions
NO156410C (en
NO156410B (en
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO834759L publication Critical patent/NO834759L/en
Publication of NO156410B publication Critical patent/NO156410B/en
Publication of NO156410C publication Critical patent/NO156410C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Novel 6 alpha -methylprednisolone derivatives of the general formula I <IMAGE> (in which R1 represents C2-C6-I-oxoalkyl or benzoyl and R2 represents H, C2-C6- I-oxoalkyl or benzoyl) and a process for their manufacture. The novel compounds are useful in the treatment of skin disorders and of allergic disorders of the respiratory and intestinal tracts.
NO834759A 1982-12-23 1983-12-22 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 6AAA METHYLPREDNISOLON DERIVATIVES. NO156410C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823248435 DE3248435A1 (en) 1982-12-23 1982-12-23 NEW 6 (ALPHA) METHYLPREDNISOLONE DERIVATIVES THEIR PRODUCTION AND USE

Publications (3)

Publication Number Publication Date
NO834759L true NO834759L (en) 1984-06-25
NO156410B NO156410B (en) 1987-06-09
NO156410C NO156410C (en) 1987-09-30

Family

ID=6182025

Family Applications (1)

Application Number Title Priority Date Filing Date
NO834759A NO156410C (en) 1982-12-23 1983-12-22 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 6AAA METHYLPREDNISOLON DERIVATIVES.

Country Status (21)

Country Link
EP (1) EP0112467B1 (en)
JP (1) JPS59130300A (en)
AT (1) ATE28878T1 (en)
AU (1) AU2220283A (en)
CA (1) CA1250571A (en)
CS (1) CS236900B2 (en)
DD (1) DD210694A5 (en)
DE (2) DE3248435A1 (en)
DK (1) DK159118C (en)
ES (1) ES528323A0 (en)
GB (1) GB2132620B (en)
GR (1) GR79453B (en)
HU (1) HU187939B (en)
IE (1) IE56400B1 (en)
IL (1) IL70452A (en)
NO (1) NO156410C (en)
PL (1) PL141513B1 (en)
PT (1) PT77880B (en)
RO (1) RO88666A (en)
SU (1) SU1299514A3 (en)
ZA (1) ZA839573B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19644679C2 (en) * 1996-10-28 1999-06-02 Freudenberg Carl Fa Mop cover

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1026160A (en) * 1964-04-29 1966-04-14 American Cyanamid Co Pregnatrienes
DE2645104C2 (en) * 1976-10-04 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen 11β-Hydroxy-1,4,8-pregnatriene-3,20-dione derivatives and processes for their preparation

Also Published As

Publication number Publication date
PL245246A1 (en) 1984-10-22
EP0112467B1 (en) 1987-08-12
PL141513B1 (en) 1987-08-31
JPS59130300A (en) 1984-07-26
CA1250571A (en) 1989-02-28
DE3372970D1 (en) 1987-09-17
RO88666A (en) 1986-02-28
JPH0415800B2 (en) 1992-03-19
ES8502128A1 (en) 1985-01-01
PT77880A (en) 1984-01-01
ZA839573B (en) 1984-08-29
PT77880B (en) 1986-04-09
NO156410C (en) 1987-09-30
GR79453B (en) 1984-10-30
IL70452A (en) 1987-12-31
CS236900B2 (en) 1985-05-15
HU187939B (en) 1986-03-28
IL70452A0 (en) 1984-03-30
NO156410B (en) 1987-06-09
AU2220283A (en) 1984-06-28
SU1299514A3 (en) 1987-03-23
GB2132620A (en) 1984-07-11
GB8333741D0 (en) 1984-01-25
ATE28878T1 (en) 1987-08-15
DK159118C (en) 1991-02-11
DK159118B (en) 1990-09-03
DK597783D0 (en) 1983-12-23
EP0112467A1 (en) 1984-07-04
IE832944L (en) 1984-06-23
DE3248435A1 (en) 1984-06-28
IE56400B1 (en) 1991-07-17
ES528323A0 (en) 1985-01-01
DK597783A (en) 1984-06-24
DD210694A5 (en) 1984-06-20
GB2132620B (en) 1986-06-04

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