CS233740B2 - Processing of 3-benzazepin compositions - Google Patents

Processing of 3-benzazepin compositions Download PDF

Info

Publication number
CS233740B2
CS233740B2 CS828075A CS807582A CS233740B2 CS 233740 B2 CS233740 B2 CS 233740B2 CS 828075 A CS828075 A CS 828075A CS 807582 A CS807582 A CS 807582A CS 233740 B2 CS233740 B2 CS 233740B2
Authority
CS
Czechoslovakia
Prior art keywords
benzazepine
chloro
compounds
solution
pressure
Prior art date
Application number
CS828075A
Other languages
Czech (cs)
English (en)
Inventor
Robert M Demarinis
Jacob P Hieble
William D Matthews
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of CS233740B2 publication Critical patent/CS233740B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CS828075A 1981-11-27 1982-11-12 Processing of 3-benzazepin compositions CS233740B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32524981A 1981-11-27 1981-11-27

Publications (1)

Publication Number Publication Date
CS233740B2 true CS233740B2 (en) 1985-03-14

Family

ID=23267072

Family Applications (1)

Application Number Title Priority Date Filing Date
CS828075A CS233740B2 (en) 1981-11-27 1982-11-12 Processing of 3-benzazepin compositions

Country Status (6)

Country Link
JP (1) JPS5892616A (xx)
KR (1) KR840002358A (xx)
CS (1) CS233740B2 (xx)
HU (1) HU190648B (xx)
SU (1) SU1238732A3 (xx)
ZA (1) ZA827887B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP1633720A1 (en) 2003-06-17 2006-03-15 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
EP2332921B1 (en) 2003-06-17 2016-03-02 Arena Pharmaceuticals, Inc. 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
JP4886700B2 (ja) 2004-12-23 2012-02-29 アリーナ ファーマシューティカルズ， インコーポレイテッド ５ｈｔ２ｃレセプターモジュレーターの組成物およびその使用方法
CN101466684B (zh) * 2006-04-03 2012-06-20 艾尼纳制药公司 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备工艺和其相关中间体
ES2522587T3 (es) 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma
EP2288585A1 (en) 2008-03-04 2011-03-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EA201390335A1 (ru) 2010-09-01 2013-09-30 Арена Фармасьютикалз, Инк. Введение лоркасерина индивидуумам с почечной недостаточностью
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
AU2012392187B2 (en) 2012-10-09 2018-07-12 Arena Pharmaceuticals, Inc. Method of weight management

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265890A (en) * 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
ZA827887B (en) 1983-11-30
HU190648B (en) 1986-09-29
JPS5892616A (ja) 1983-06-02
KR840002358A (ko) 1984-06-25
SU1238732A3 (ru) 1986-06-15

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