ZA827887B - Pharmaceutical compositions and method of producing alpha2 antagonism - Google Patents

Pharmaceutical compositions and method of producing alpha2 antagonism

Info

Publication number
ZA827887B
ZA827887B ZA827887A ZA827887A ZA827887B ZA 827887 B ZA827887 B ZA 827887B ZA 827887 A ZA827887 A ZA 827887A ZA 827887 A ZA827887 A ZA 827887A ZA 827887 B ZA827887 B ZA 827887B
Authority
ZA
South Africa
Prior art keywords
producing
pharmaceutical compositions
alpha2
antagonism
alpha2 antagonism
Prior art date
Application number
ZA827887A
Other languages
English (en)
Inventor
Robert Michael Demarinis
Jacob Paul Hieble
William David Matthews
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA827887B publication Critical patent/ZA827887B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
ZA827887A 1981-11-27 1982-10-28 Pharmaceutical compositions and method of producing alpha2 antagonism ZA827887B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32524981A 1981-11-27 1981-11-27

Publications (1)

Publication Number Publication Date
ZA827887B true ZA827887B (en) 1983-11-30

Family

ID=23267072

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA827887A ZA827887B (en) 1981-11-27 1982-10-28 Pharmaceutical compositions and method of producing alpha2 antagonism

Country Status (6)

Country Link
JP (1) JPS5892616A (xx)
KR (1) KR840002358A (xx)
CS (1) CS233740B2 (xx)
HU (1) HU190648B (xx)
SU (1) SU1238732A3 (xx)
ZA (1) ZA827887B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP1633720A1 (en) 2003-06-17 2006-03-15 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
EP2332921B1 (en) 2003-06-17 2016-03-02 Arena Pharmaceuticals, Inc. 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
JP4886700B2 (ja) 2004-12-23 2012-02-29 アリーナ ファーマシューティカルズ， インコーポレイテッド ５ｈｔ２ｃレセプターモジュレーターの組成物およびその使用方法
CN101466684B (zh) * 2006-04-03 2012-06-20 艾尼纳制药公司 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备工艺和其相关中间体
ES2522587T3 (es) 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma
EP2288585A1 (en) 2008-03-04 2011-03-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EA201390335A1 (ru) 2010-09-01 2013-09-30 Арена Фармасьютикалз, Инк. Введение лоркасерина индивидуумам с почечной недостаточностью
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
AU2012392187B2 (en) 2012-10-09 2018-07-12 Arena Pharmaceuticals, Inc. Method of weight management

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265890A (en) * 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
CS233740B2 (en) 1985-03-14
HU190648B (en) 1986-09-29
JPS5892616A (ja) 1983-06-02
KR840002358A (ko) 1984-06-25
SU1238732A3 (ru) 1986-06-15

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