CS228536B2 - Production method of 3-aryl-5-isothiazole - Google Patents
Production method of 3-aryl-5-isothiazole Download PDFInfo
- Publication number
- CS228536B2 CS228536B2 CS816978A CS697881A CS228536B2 CS 228536 B2 CS228536 B2 CS 228536B2 CS 816978 A CS816978 A CS 816978A CS 697881 A CS697881 A CS 697881A CS 228536 B2 CS228536 B2 CS 228536B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- acid
- amino
- formula
- methyl
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/189,435 US4346094A (en) | 1980-09-22 | 1980-09-22 | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS228536B2 true CS228536B2 (en) | 1984-05-14 |
Family
ID=22697314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS816978A CS228536B2 (en) | 1980-09-22 | 1981-09-22 | Production method of 3-aryl-5-isothiazole |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4346094A (xx) |
| EP (1) | EP0048615B1 (xx) |
| JP (1) | JPS5785379A (xx) |
| KR (1) | KR830007597A (xx) |
| AR (1) | AR229103A1 (xx) |
| AT (1) | ATE7657T1 (xx) |
| AU (1) | AU7551681A (xx) |
| CS (1) | CS228536B2 (xx) |
| DD (1) | DD201790A5 (xx) |
| DE (1) | DE3163900D1 (xx) |
| DK (1) | DK417981A (xx) |
| ES (1) | ES8301225A1 (xx) |
| FI (1) | FI812940L (xx) |
| GB (1) | GB2084573B (xx) |
| GR (1) | GR75046B (xx) |
| IL (1) | IL63890A0 (xx) |
| NO (1) | NO813208L (xx) |
| PL (1) | PL130497B1 (xx) |
| PT (1) | PT73711B (xx) |
| RO (1) | RO82216A (xx) |
| YU (1) | YU227181A (xx) |
| ZA (1) | ZA816549B (xx) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4428956A (en) | 1980-12-29 | 1984-01-31 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4431652A (en) * | 1980-12-29 | 1984-02-14 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4539328A (en) * | 1983-03-25 | 1985-09-03 | Fmc Corporation | Nematicidal isothiazole derivatives |
| US4620865A (en) * | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| IE59813B1 (en) * | 1986-05-09 | 1994-04-06 | Warner Lambert Co | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them |
| ZW21687A1 (en) * | 1986-12-12 | 1988-07-20 | Hoffmann La Roche | Triazine derivatives |
| CA2073981C (en) * | 1990-11-30 | 2002-01-08 | Shiro Kondo | 2-arylthiazole derivatives and pharmaceutical composition thereof |
| US5294630A (en) * | 1992-07-07 | 1994-03-15 | Eli Lilly And Company | Treatment of inflammatory bowel disease |
| US5436258A (en) * | 1992-09-09 | 1995-07-25 | Eli Lilly And Company | Prevention of bone resorption |
| MY117352A (en) * | 1995-10-31 | 2004-06-30 | Ciba Sc Holding Ag | Oximesulfonic acid esters and the use thereof as latent sulfonic acids. |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
| AU1520699A (en) | 1997-11-07 | 1999-05-31 | Johns Hopkins University, The | Methods for treatment of disorders of cardiac contractility |
| TW575792B (en) * | 1998-08-19 | 2004-02-11 | Ciba Sc Holding Ag | New unsaturated oxime derivatives and the use thereof as latent acids |
| SG78412A1 (en) | 1999-03-31 | 2001-02-20 | Ciba Sc Holding Ag | Oxime derivatives and the use thereof as latent acids |
| CN100475798C (zh) | 2002-02-06 | 2009-04-08 | 西巴特殊化学品控股有限公司 | 磺酸衍生物及其作为潜酸的用途 |
| US7820700B2 (en) * | 2004-08-27 | 2010-10-26 | Astellas Pharma Inc. | 2-phenylpyridine derivative |
| WO2006022375A1 (ja) * | 2004-08-27 | 2006-03-02 | Astellas Pharma Inc. | ２－フェニルチオフェン誘導体 |
| WO2007043457A1 (ja) | 2005-10-07 | 2007-04-19 | Astellas Pharma Inc. | トリアリールカルボン酸誘導体 |
| US8067446B2 (en) | 2006-02-24 | 2011-11-29 | Astellas Pharma Inc. | Methods for treating an ulcer of the small intestine and stomach |
| GB2450975B (en) | 2007-07-12 | 2010-02-24 | Ciba Holding Inc | Yellow radiation curing inks |
| MX2011008348A (es) | 2009-02-27 | 2011-09-01 | Teijin Pharma Ltd | Proceso para producir derivado heterociclico sustituido con fenilo a traves de acoplamiento usando catalizador de metal de transicion. |
| EP2414894B1 (en) | 2009-03-30 | 2014-02-12 | Basf Se | Uv-dose indicator films |
| PT2610248T (pt) | 2010-08-27 | 2016-08-23 | Teijin Pharma Ltd | Método para produção de derivado heterocíclico substituído por fenilo por meio de método de acoplamento usando um composto de paládio |
| CN103443072B (zh) | 2011-01-28 | 2016-05-18 | 巴斯夫欧洲公司 | 包含肟磺酸酯作为热固化剂的可聚合组合物 |
| LT2980085T (lt) * | 2013-03-29 | 2018-05-10 | Teijin Pharma Limited | Pirazolo darinys |
| JP6664383B2 (ja) | 2014-08-29 | 2020-03-13 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | オキシムスルホネート誘導体 |
| BR112017023170B1 (pt) | 2015-04-29 | 2022-08-16 | Bsn Medical Gmbh | Dispositivo de banho medicinal e seu uso |
| EP3288893B8 (de) | 2015-04-29 | 2019-04-10 | BSN medical GmbH | Mehrstufiges verfahren zur no-herstellung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1178604A (en) * | 1966-03-21 | 1970-01-21 | American Cyanamid Co | Novel Pyridinium Salts and Methods for Preparing Same |
| US3464999A (en) * | 1967-07-27 | 1969-09-02 | R & L Molecular Research Ltd | Thiadiazolylisothiazoles |
| GB1180268A (en) * | 1967-09-26 | 1970-02-04 | Ici Ltd | Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives |
| GB1192701A (en) * | 1968-03-22 | 1970-05-20 | Ici Ltd | Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same |
| US3681498A (en) * | 1970-10-19 | 1972-08-01 | American Cyanamid Co | Isothiazolyl pyridinium salts as hypoglycemic agents |
-
1980
- 1980-09-22 US US06/189,435 patent/US4346094A/en not_active Expired - Lifetime
-
1981
- 1981-09-19 PL PL1981233103A patent/PL130497B1/pl unknown
- 1981-09-20 IL IL63890A patent/IL63890A0/xx unknown
- 1981-09-21 DE DE8181304325T patent/DE3163900D1/de not_active Expired
- 1981-09-21 DK DK417981A patent/DK417981A/da not_active Application Discontinuation
- 1981-09-21 AU AU75516/81A patent/AU7551681A/en not_active Abandoned
- 1981-09-21 ES ES505678A patent/ES8301225A1/es not_active Expired
- 1981-09-21 AT AT81304325T patent/ATE7657T1/de not_active IP Right Cessation
- 1981-09-21 GR GR66108A patent/GR75046B/el unknown
- 1981-09-21 EP EP81304325A patent/EP0048615B1/en not_active Expired
- 1981-09-21 GB GB8128465A patent/GB2084573B/en not_active Expired
- 1981-09-21 NO NO813208A patent/NO813208L/no unknown
- 1981-09-21 YU YU02271/81A patent/YU227181A/xx unknown
- 1981-09-21 AR AR286818A patent/AR229103A1/es active
- 1981-09-21 PT PT73711A patent/PT73711B/pt unknown
- 1981-09-21 ZA ZA816549A patent/ZA816549B/xx unknown
- 1981-09-21 FI FI812940A patent/FI812940L/fi not_active Application Discontinuation
- 1981-09-21 RO RO81105346A patent/RO82216A/ro unknown
- 1981-09-22 CS CS816978A patent/CS228536B2/cs unknown
- 1981-09-22 JP JP56150483A patent/JPS5785379A/ja active Pending
- 1981-09-22 KR KR1019810003537A patent/KR830007597A/ko unknown
- 1981-09-22 DD DD81233487A patent/DD201790A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0048615A1 (en) | 1982-03-31 |
| GB2084573B (en) | 1984-09-12 |
| YU227181A (en) | 1983-10-31 |
| KR830007597A (ko) | 1983-11-04 |
| PT73711A (en) | 1981-10-01 |
| EP0048615B1 (en) | 1984-05-30 |
| RO82216B (ro) | 1983-06-30 |
| FI812940L (fi) | 1982-03-23 |
| IL63890A0 (en) | 1981-12-31 |
| PL233103A1 (xx) | 1982-12-20 |
| ES505678A0 (es) | 1982-12-01 |
| ZA816549B (en) | 1983-04-27 |
| US4346094A (en) | 1982-08-24 |
| PT73711B (en) | 1982-12-20 |
| DE3163900D1 (en) | 1984-07-05 |
| GB2084573A (en) | 1982-04-15 |
| NO813208L (no) | 1982-03-23 |
| GR75046B (xx) | 1984-07-12 |
| JPS5785379A (en) | 1982-05-28 |
| RO82216A (ro) | 1983-07-07 |
| ATE7657T1 (de) | 1984-06-15 |
| DD201790A5 (de) | 1983-08-10 |
| PL130497B1 (en) | 1984-08-31 |
| AR229103A1 (es) | 1983-06-15 |
| AU7551681A (en) | 1982-04-01 |
| DK417981A (da) | 1982-03-23 |
| ES8301225A1 (es) | 1982-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS228536B2 (en) | Production method of 3-aryl-5-isothiazole | |
| US5596013A (en) | Dihydro pyrazolopyrroles | |
| US4943587A (en) | Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues and their use for cyclooxygenase and 5-lipoxygenase inhibition | |
| US5459151A (en) | N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents | |
| US4495195A (en) | Xanthine oxidase inhibiting 3(5)-phenyl-substituted-5(3)-pyrazole-carboxylic acid derivatives, compositions, and methods of use | |
| RU2184731C2 (ru) | Амиды аминотиофенкарбоновой кислоты, способ их получения (варианты) и фармацевтическая композиция | |
| AU684887B2 (en) | Isoxazoline compounds as inhibitors of TNF release | |
| US4861891A (en) | Antidepressant N-substituted nicotinamide compounds | |
| US5011849A (en) | Compounds for treating and preventing cognitive diseases and depression and methods of making same | |
| BG60402B2 (bg) | Заместени бициклични съединения | |
| IL111670A (en) | Isoxazoline compounds as anti-inflammatory substances | |
| NO760993L (xx) | ||
| JP2001354563A (ja) | 置換ベンジルアミン類を含有する医薬 | |
| BRPI0618131A2 (pt) | derivado de alquilcarbamoil naftalenilóxi-octenoilidroxiamida tendo atividade inibitória contra histona desacetilase e sua preparação | |
| US5204482A (en) | Compounds for treating and preventing cognitive diseases and depression and methods of making same | |
| US6469003B1 (en) | Pyridazinone derivatives | |
| US5112868A (en) | Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition | |
| US4181661A (en) | Derivatives of 2-iminothiazolidines and thiazolines | |
| US4652565A (en) | Piperazine derivatives, their production and pharmaceutical compositions containing them | |
| US4544752A (en) | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels | |
| US5250700A (en) | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents | |
| HU201015B (en) | Process for producing pyridine derivatives | |
| US5418236A (en) | Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles | |
| US4935434A (en) | Antiarthritic isoxazole-4-carboxamides | |
| US4588725A (en) | 2-piperazinyl-quinazoline derivatives and pharmaceutical compositions containing them |