CS228536B2 - Production method of 3-aryl-5-isothiazole - Google Patents
Production method of 3-aryl-5-isothiazole Download PDFInfo
- Publication number
- CS228536B2 CS228536B2 CS816978A CS697881A CS228536B2 CS 228536 B2 CS228536 B2 CS 228536B2 CS 816978 A CS816978 A CS 816978A CS 697881 A CS697881 A CS 697881A CS 228536 B2 CS228536 B2 CS 228536B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- acid
- amino
- formula
- methyl
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/189,435 US4346094A (en) | 1980-09-22 | 1980-09-22 | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS228536B2 true CS228536B2 (en) | 1984-05-14 |
Family
ID=22697314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS816978A CS228536B2 (en) | 1980-09-22 | 1981-09-22 | Production method of 3-aryl-5-isothiazole |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4346094A (pm) |
| EP (1) | EP0048615B1 (pm) |
| JP (1) | JPS5785379A (pm) |
| KR (1) | KR830007597A (pm) |
| AR (1) | AR229103A1 (pm) |
| AT (1) | ATE7657T1 (pm) |
| AU (1) | AU7551681A (pm) |
| CS (1) | CS228536B2 (pm) |
| DD (1) | DD201790A5 (pm) |
| DE (1) | DE3163900D1 (pm) |
| DK (1) | DK417981A (pm) |
| ES (1) | ES8301225A1 (pm) |
| FI (1) | FI812940A7 (pm) |
| GB (1) | GB2084573B (pm) |
| GR (1) | GR75046B (pm) |
| IL (1) | IL63890A0 (pm) |
| NO (1) | NO813208L (pm) |
| PL (1) | PL130497B1 (pm) |
| PT (1) | PT73711B (pm) |
| RO (1) | RO82216A (pm) |
| YU (1) | YU227181A (pm) |
| ZA (1) | ZA816549B (pm) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431652A (en) * | 1980-12-29 | 1984-02-14 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4428956A (en) | 1980-12-29 | 1984-01-31 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4539328A (en) * | 1983-03-25 | 1985-09-03 | Fmc Corporation | Nematicidal isothiazole derivatives |
| US4620865A (en) * | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| IE59813B1 (en) * | 1986-05-09 | 1994-04-06 | Warner Lambert Co | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them |
| ZW21687A1 (en) * | 1986-12-12 | 1988-07-20 | Hoffmann La Roche | Triazine derivatives |
| KR100221041B1 (ko) * | 1990-11-30 | 1999-09-15 | 야스이 쇼사꾸 | 2-아릴티아졸 유도체 및 그의 약제학적 조성물 |
| US5294630A (en) * | 1992-07-07 | 1994-03-15 | Eli Lilly And Company | Treatment of inflammatory bowel disease |
| US5436258A (en) * | 1992-09-09 | 1995-07-25 | Eli Lilly And Company | Prevention of bone resorption |
| MY117352A (en) * | 1995-10-31 | 2004-06-30 | Ciba Sc Holding Ag | Oximesulfonic acid esters and the use thereof as latent sulfonic acids. |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
| WO1999024038A1 (en) | 1997-11-07 | 1999-05-20 | Johns Hopkins University | Methods for treatment of disorders of cardiac contractility |
| TW575792B (en) * | 1998-08-19 | 2004-02-11 | Ciba Sc Holding Ag | New unsaturated oxime derivatives and the use thereof as latent acids |
| SG78412A1 (en) | 1999-03-31 | 2001-02-20 | Ciba Sc Holding Ag | Oxime derivatives and the use thereof as latent acids |
| EP1472576B1 (en) | 2002-02-06 | 2013-04-24 | Basf Se | Sulfonate derivatives and the use therof as latent acids |
| WO2006022375A1 (ja) * | 2004-08-27 | 2006-03-02 | Astellas Pharma Inc. | ２－フェニルチオフェン誘導体 |
| WO2006022374A1 (ja) * | 2004-08-27 | 2006-03-02 | Astellas Pharma Inc. | ２－フェニルピリジン誘導体 |
| DE602006018635D1 (de) | 2005-10-07 | 2011-01-13 | Astellas Pharma Inc | Triarylcarbonsäurederivat |
| PT1992361E (pt) | 2006-02-24 | 2012-07-10 | Astellas Pharma Inc | Medicamento ou agente preventivo contra úlceras digestivas |
| GB2450975B (en) | 2007-07-12 | 2010-02-24 | Ciba Holding Inc | Yellow radiation curing inks |
| EP2291189B1 (en) * | 2008-05-22 | 2014-10-01 | AstraZeneca AB | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
| CN102333765B (zh) | 2009-02-27 | 2015-01-14 | 帝人制药株式会社 | 基于使用过渡金属催化剂的偶联法的苯基取代杂环衍生物的制造方法 |
| KR20110137821A (ko) | 2009-03-30 | 2011-12-23 | 바스프 에스이 | Ｕｖ-조사량 인디케이터 필름 |
| DK2610248T3 (en) | 2010-08-27 | 2016-07-25 | Teijin Pharma Ltd | PROCESS FOR THE PREPARATION OF PHENYL-substituted heterocyclic derivative by means of the coupling method using a palladium compound |
| US9310677B2 (en) | 2011-01-28 | 2016-04-12 | Basf | Polymerizable composition comprising an oxime sulfonate as thermal curing agent |
| MX363191B (es) * | 2013-03-29 | 2019-03-14 | Teijin Pharma Ltd | Derivado de pirazol. |
| US10487050B2 (en) | 2014-08-29 | 2019-11-26 | Basf Se | Oxime sulfonate derivatives |
| AU2016256186B2 (en) | 2015-04-29 | 2020-01-16 | Bsn Medical Gmbh | Multi-step process for no production |
| CA2984033C (en) | 2015-04-29 | 2023-08-15 | Bsn Medical Gmbh | Medical bathing equipment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1178604A (en) * | 1966-03-21 | 1970-01-21 | American Cyanamid Co | Novel Pyridinium Salts and Methods for Preparing Same |
| US3464999A (en) * | 1967-07-27 | 1969-09-02 | R & L Molecular Research Ltd | Thiadiazolylisothiazoles |
| GB1180268A (en) * | 1967-09-26 | 1970-02-04 | Ici Ltd | Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives |
| GB1192701A (en) * | 1968-03-22 | 1970-05-20 | Ici Ltd | Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same |
| US3681498A (en) * | 1970-10-19 | 1972-08-01 | American Cyanamid Co | Isothiazolyl pyridinium salts as hypoglycemic agents |
-
1980
- 1980-09-22 US US06/189,435 patent/US4346094A/en not_active Expired - Lifetime
-
1981
- 1981-09-19 PL PL1981233103A patent/PL130497B1/pl unknown
- 1981-09-20 IL IL63890A patent/IL63890A0/xx unknown
- 1981-09-21 ES ES505678A patent/ES8301225A1/es not_active Expired
- 1981-09-21 EP EP81304325A patent/EP0048615B1/en not_active Expired
- 1981-09-21 DK DK417981A patent/DK417981A/da not_active Application Discontinuation
- 1981-09-21 AT AT81304325T patent/ATE7657T1/de not_active IP Right Cessation
- 1981-09-21 DE DE8181304325T patent/DE3163900D1/de not_active Expired
- 1981-09-21 GR GR66108A patent/GR75046B/el unknown
- 1981-09-21 AR AR286818A patent/AR229103A1/es active
- 1981-09-21 GB GB8128465A patent/GB2084573B/en not_active Expired
- 1981-09-21 RO RO81105346A patent/RO82216A/ro unknown
- 1981-09-21 PT PT73711A patent/PT73711B/pt unknown
- 1981-09-21 ZA ZA816549A patent/ZA816549B/xx unknown
- 1981-09-21 AU AU75516/81A patent/AU7551681A/en not_active Abandoned
- 1981-09-21 FI FI812940A patent/FI812940A7/fi not_active Application Discontinuation
- 1981-09-21 YU YU02271/81A patent/YU227181A/xx unknown
- 1981-09-21 NO NO813208A patent/NO813208L/no unknown
- 1981-09-22 KR KR1019810003537A patent/KR830007597A/ko not_active Abandoned
- 1981-09-22 CS CS816978A patent/CS228536B2/cs unknown
- 1981-09-22 JP JP56150483A patent/JPS5785379A/ja active Pending
- 1981-09-22 DD DD81233487A patent/DD201790A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES505678A0 (es) | 1982-12-01 |
| GB2084573B (en) | 1984-09-12 |
| DK417981A (da) | 1982-03-23 |
| RO82216A (ro) | 1983-07-07 |
| FI812940L (fi) | 1982-03-23 |
| AU7551681A (en) | 1982-04-01 |
| PT73711A (en) | 1981-10-01 |
| JPS5785379A (en) | 1982-05-28 |
| PL233103A1 (pm) | 1982-12-20 |
| IL63890A0 (en) | 1981-12-31 |
| FI812940A7 (fi) | 1982-03-23 |
| DE3163900D1 (en) | 1984-07-05 |
| GB2084573A (en) | 1982-04-15 |
| ZA816549B (en) | 1983-04-27 |
| ES8301225A1 (es) | 1982-12-01 |
| ATE7657T1 (de) | 1984-06-15 |
| KR830007597A (ko) | 1983-11-04 |
| EP0048615B1 (en) | 1984-05-30 |
| US4346094A (en) | 1982-08-24 |
| YU227181A (en) | 1983-10-31 |
| DD201790A5 (de) | 1983-08-10 |
| NO813208L (no) | 1982-03-23 |
| RO82216B (ro) | 1983-06-30 |
| PL130497B1 (en) | 1984-08-31 |
| AR229103A1 (es) | 1983-06-15 |
| PT73711B (en) | 1982-12-20 |
| GR75046B (pm) | 1984-07-12 |
| EP0048615A1 (en) | 1982-03-31 |
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