CS228536B2 - Production method of 3-aryl-5-isothiazole - Google Patents
Production method of 3-aryl-5-isothiazole Download PDFInfo
- Publication number
- CS228536B2 CS228536B2 CS816978A CS697881A CS228536B2 CS 228536 B2 CS228536 B2 CS 228536B2 CS 816978 A CS816978 A CS 816978A CS 697881 A CS697881 A CS 697881A CS 228536 B2 CS228536 B2 CS 228536B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- acid
- amino
- formula
- methyl
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/189,435 US4346094A (en) | 1980-09-22 | 1980-09-22 | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS228536B2 true CS228536B2 (en) | 1984-05-14 |
Family
ID=22697314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS816978A CS228536B2 (en) | 1980-09-22 | 1981-09-22 | Production method of 3-aryl-5-isothiazole |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4346094A (de) |
| EP (1) | EP0048615B1 (de) |
| JP (1) | JPS5785379A (de) |
| KR (1) | KR830007597A (de) |
| AR (1) | AR229103A1 (de) |
| AT (1) | ATE7657T1 (de) |
| AU (1) | AU7551681A (de) |
| CS (1) | CS228536B2 (de) |
| DD (1) | DD201790A5 (de) |
| DE (1) | DE3163900D1 (de) |
| DK (1) | DK417981A (de) |
| ES (1) | ES8301225A1 (de) |
| FI (1) | FI812940A7 (de) |
| GB (1) | GB2084573B (de) |
| GR (1) | GR75046B (de) |
| IL (1) | IL63890A0 (de) |
| NO (1) | NO813208L (de) |
| PL (1) | PL130497B1 (de) |
| PT (1) | PT73711B (de) |
| RO (1) | RO82216A (de) |
| YU (1) | YU227181A (de) |
| ZA (1) | ZA816549B (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431652A (en) * | 1980-12-29 | 1984-02-14 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4428956A (en) | 1980-12-29 | 1984-01-31 | Merck & Co., Inc. | 4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis |
| US4539328A (en) * | 1983-03-25 | 1985-09-03 | Fmc Corporation | Nematicidal isothiazole derivatives |
| US4620865A (en) * | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| IE59813B1 (en) * | 1986-05-09 | 1994-04-06 | Warner Lambert Co | Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them |
| ZW21687A1 (en) * | 1986-12-12 | 1988-07-20 | Hoffmann La Roche | Triazine derivatives |
| ATE142494T1 (de) * | 1990-11-30 | 1996-09-15 | Teijin Ltd | 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel |
| US5294630A (en) * | 1992-07-07 | 1994-03-15 | Eli Lilly And Company | Treatment of inflammatory bowel disease |
| US5436258A (en) * | 1992-09-09 | 1995-07-25 | Eli Lilly And Company | Prevention of bone resorption |
| MY117352A (en) * | 1995-10-31 | 2004-06-30 | Ciba Sc Holding Ag | Oximesulfonic acid esters and the use thereof as latent sulfonic acids. |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
| AU1520699A (en) | 1997-11-07 | 1999-05-31 | Johns Hopkins University, The | Methods for treatment of disorders of cardiac contractility |
| TW575792B (en) * | 1998-08-19 | 2004-02-11 | Ciba Sc Holding Ag | New unsaturated oxime derivatives and the use thereof as latent acids |
| SG78412A1 (en) | 1999-03-31 | 2001-02-20 | Ciba Sc Holding Ag | Oxime derivatives and the use thereof as latent acids |
| KR20040089607A (ko) | 2002-02-06 | 2004-10-21 | 시바 스페셜티 케미칼스 홀딩 인크. | 설포네이트 유도체 및 잠산으로서의 이의 용도 |
| US7820700B2 (en) * | 2004-08-27 | 2010-10-26 | Astellas Pharma Inc. | 2-phenylpyridine derivative |
| WO2006022375A1 (ja) * | 2004-08-27 | 2006-03-02 | Astellas Pharma Inc. | ２－フェニルチオフェン誘導体 |
| WO2007043457A1 (ja) | 2005-10-07 | 2007-04-19 | Astellas Pharma Inc. | トリアリールカルボン酸誘導体 |
| MX2008010646A (es) | 2006-02-24 | 2008-10-14 | Astellas Pharma Inc | Agente para tratar o prevenir ulcera digestiva. |
| GB2450975B (en) | 2007-07-12 | 2010-02-24 | Ciba Holding Inc | Yellow radiation curing inks |
| CA2725047A1 (en) * | 2008-05-22 | 2009-11-26 | Bristol-Myers Squibb Company | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
| US8952174B2 (en) | 2009-02-27 | 2015-02-10 | Teijin Pharma Limited | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst |
| JP2012522084A (ja) | 2009-03-30 | 2012-09-20 | ビーエーエスエフ ソシエタス・ヨーロピア | Ｕｖ線量インジケータフィルム |
| AU2011294204B2 (en) | 2010-08-27 | 2015-07-23 | Teijin Limited | Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using a palladium compound |
| JP5955339B2 (ja) | 2011-01-28 | 2016-07-20 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | 熱硬化剤としてオキシムスルホネートを含む重合性組成物 |
| NZ712680A (en) * | 2013-03-29 | 2020-02-28 | Teijin Pharma Ltd | Pyrazole derivative |
| KR20170048422A (ko) | 2014-08-29 | 2017-05-08 | 바스프 에스이 | 옥심 술포네이트 유도체 |
| AU2016256577B2 (en) | 2015-04-29 | 2019-04-04 | Bsn Medical Gmbh | Medical bathing device |
| US20180116920A1 (en) | 2015-04-29 | 2018-05-03 | Bsn Medical Gmbh | Multi-step process for no production |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1178604A (en) * | 1966-03-21 | 1970-01-21 | American Cyanamid Co | Novel Pyridinium Salts and Methods for Preparing Same |
| US3464999A (en) * | 1967-07-27 | 1969-09-02 | R & L Molecular Research Ltd | Thiadiazolylisothiazoles |
| GB1180268A (en) * | 1967-09-26 | 1970-02-04 | Ici Ltd | Pharmaceutically Active Phenyl-Heterocyclic-Alkanol Derivatives |
| GB1192701A (en) * | 1968-03-22 | 1970-05-20 | Ici Ltd | Novel Thiazole Derivatives, the preparation thereof and Compositions containing the same |
| US3681498A (en) * | 1970-10-19 | 1972-08-01 | American Cyanamid Co | Isothiazolyl pyridinium salts as hypoglycemic agents |
-
1980
- 1980-09-22 US US06/189,435 patent/US4346094A/en not_active Expired - Lifetime
-
1981
- 1981-09-19 PL PL1981233103A patent/PL130497B1/pl unknown
- 1981-09-20 IL IL63890A patent/IL63890A0/xx unknown
- 1981-09-21 GB GB8128465A patent/GB2084573B/en not_active Expired
- 1981-09-21 RO RO81105346A patent/RO82216A/ro unknown
- 1981-09-21 AT AT81304325T patent/ATE7657T1/de not_active IP Right Cessation
- 1981-09-21 ZA ZA816549A patent/ZA816549B/xx unknown
- 1981-09-21 AR AR286818A patent/AR229103A1/es active
- 1981-09-21 FI FI812940A patent/FI812940A7/fi not_active Application Discontinuation
- 1981-09-21 NO NO813208A patent/NO813208L/no unknown
- 1981-09-21 ES ES505678A patent/ES8301225A1/es not_active Expired
- 1981-09-21 EP EP81304325A patent/EP0048615B1/de not_active Expired
- 1981-09-21 YU YU02271/81A patent/YU227181A/xx unknown
- 1981-09-21 AU AU75516/81A patent/AU7551681A/en not_active Abandoned
- 1981-09-21 DE DE8181304325T patent/DE3163900D1/de not_active Expired
- 1981-09-21 PT PT73711A patent/PT73711B/pt unknown
- 1981-09-21 DK DK417981A patent/DK417981A/da not_active Application Discontinuation
- 1981-09-21 GR GR66108A patent/GR75046B/el unknown
- 1981-09-22 KR KR1019810003537A patent/KR830007597A/ko not_active Abandoned
- 1981-09-22 JP JP56150483A patent/JPS5785379A/ja active Pending
- 1981-09-22 DD DD81233487A patent/DD201790A5/de unknown
- 1981-09-22 CS CS816978A patent/CS228536B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU227181A (en) | 1983-10-31 |
| NO813208L (no) | 1982-03-23 |
| KR830007597A (ko) | 1983-11-04 |
| DK417981A (da) | 1982-03-23 |
| JPS5785379A (en) | 1982-05-28 |
| PL130497B1 (en) | 1984-08-31 |
| DE3163900D1 (en) | 1984-07-05 |
| RO82216A (ro) | 1983-07-07 |
| RO82216B (ro) | 1983-06-30 |
| ZA816549B (en) | 1983-04-27 |
| US4346094A (en) | 1982-08-24 |
| IL63890A0 (en) | 1981-12-31 |
| PL233103A1 (de) | 1982-12-20 |
| AU7551681A (en) | 1982-04-01 |
| FI812940L (fi) | 1982-03-23 |
| ES505678A0 (es) | 1982-12-01 |
| GR75046B (de) | 1984-07-12 |
| ES8301225A1 (es) | 1982-12-01 |
| PT73711B (en) | 1982-12-20 |
| EP0048615A1 (de) | 1982-03-31 |
| EP0048615B1 (de) | 1984-05-30 |
| PT73711A (en) | 1981-10-01 |
| DD201790A5 (de) | 1983-08-10 |
| FI812940A7 (fi) | 1982-03-23 |
| GB2084573B (en) | 1984-09-12 |
| ATE7657T1 (de) | 1984-06-15 |
| GB2084573A (en) | 1982-04-15 |
| AR229103A1 (es) | 1983-06-15 |
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