CS228531B2 - Method for the production of phenylpiperazine derivates - Google Patents

Method for the production of phenylpiperazine derivates Download PDF

Info

Publication number
CS228531B2
CS228531B2 CS816655A CS665581A CS228531B2 CS 228531 B2 CS228531 B2 CS 228531B2 CS 816655 A CS816655 A CS 816655A CS 665581 A CS665581 A CS 665581A CS 228531 B2 CS228531 B2 CS 228531B2
Authority
CS
Czechoslovakia
Prior art keywords
group
formula
carbon atoms
compounds
pharmaceutically acceptable
Prior art date
Application number
CS816655A
Other languages
Czech (cs)
English (en)
Inventor
Hans H Haeck
Feddo C Hillen
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of CS228531B2 publication Critical patent/CS228531B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS816655A 1980-09-12 1981-09-09 Method for the production of phenylpiperazine derivates CS228531B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8005132A NL8005132A (nl) 1980-09-12 1980-09-12 Fenylpiperazinederivaten met antiagressieve werking.

Publications (1)

Publication Number Publication Date
CS228531B2 true CS228531B2 (en) 1984-05-14

Family

ID=19835869

Family Applications (1)

Application Number Title Priority Date Filing Date
CS816655A CS228531B2 (en) 1980-09-12 1981-09-09 Method for the production of phenylpiperazine derivates

Country Status (17)

Country Link
EP (1) EP0048044A1 (fi)
JP (1) JPS5781477A (fi)
AU (1) AU7502881A (fi)
CA (1) CA1158647A (fi)
CS (1) CS228531B2 (fi)
DD (1) DD202288A5 (fi)
DK (1) DK399981A (fi)
ES (1) ES8302682A1 (fi)
FI (1) FI812807L (fi)
GR (1) GR75818B (fi)
HU (1) HU184965B (fi)
IL (1) IL63783A0 (fi)
NL (1) NL8005132A (fi)
PH (1) PH17399A (fi)
PL (1) PL232966A1 (fi)
YU (1) YU217481A (fi)
ZA (1) ZA816255B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK101683A (da) * 1982-03-12 1983-09-13 Duphar Int Res Phenylpiperazinderivater og fremgangsmaade til fremstilling heraf
US4477646A (en) * 1983-08-24 1984-10-16 The Dow Chemical Company Piperazinoethyl ureas
JP2641280B2 (ja) * 1988-12-29 1997-08-13 日本ペイント株式会社 新規な環状ウレア誘導体
JPH0735363B2 (ja) * 1990-07-03 1995-04-19 日本ペイント株式会社 不飽和カルバミン酸エステル類の製法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824530A (en) * 1972-12-05 1974-07-16 Amp Inc Installation of electrical connectors on wires intermediate the ends thereof

Also Published As

Publication number Publication date
GR75818B (fi) 1984-08-02
FI812807L (fi) 1982-03-13
JPS5781477A (en) 1982-05-21
DD202288A5 (de) 1983-09-07
AU7502881A (en) 1982-03-18
PL232966A1 (fi) 1982-10-25
ES505372A0 (es) 1982-12-01
CA1158647A (en) 1983-12-13
HU184965B (en) 1984-11-28
ES8302682A1 (es) 1982-12-01
PH17399A (en) 1984-08-08
NL8005132A (nl) 1982-04-01
DK399981A (da) 1982-03-13
ZA816255B (en) 1983-04-27
EP0048044A1 (en) 1982-03-24
YU217481A (en) 1983-09-30
IL63783A0 (en) 1981-12-31

Similar Documents

Publication Publication Date Title
EP0487408B1 (fr) Dérivés d'oxazolopyridines leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent
CH644105A5 (fr) Acides et esters 4-amino-3-quinoleinecarboxyliques, utiles notamment comme agent antisecretoires et anti-ulcere.
EP0079545B1 (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
JPS6026776B2 (ja) 新規オキシムエーテル化合物
CA2225555A1 (en) Quinolones and their therapeutic use
HU184966B (en) Process for producing phenyl-piperazine derivatives of anti-agression activity
FR2656609A1 (fr) Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.
EP0000299B1 (fr) Nouveaux dérivés de benzoyl-2-chloro-4-glycinanilides substitués, leur procédé de préparation et leur application en tant que médicaments.
DE69629341T2 (de) Pyrrolocarbazolderivate
FR2664269A1 (fr) Nouveaux derives n-substitues d'alpha-mercapto alkylamines, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant.
EP0076199B1 (fr) Nouvelles triazoloquinazolones et leurs sels, procédé et intermédiaires de préparation, leur application comme médicaments et les compositions les renfermant
FR2593818A1 (fr) Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
US4395413A (en) Oxime ethers and pharmaceutical compositions containing the same
DE69215482T2 (de) 2,2'-Alkylendiindolderivate, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung als Ulcustherapeutikum
CS228531B2 (en) Method for the production of phenylpiperazine derivates
HU182070B (en) Process for producing phenyl-piperazine derivatives
JPH04244083A (ja) 三環状ピリドン誘導体
Finkelstein et al. Synthesis of cis-and trans-2-phenoxycyclopropylamines and related compounds
AU723563B2 (en) Use of a combination of delavirdine and one or more protease inhibitors in HIV-1 infected patients
JPS6399057A (ja) グリシン誘導体
JPH0377191B2 (fi)
JPS6396187A (ja) インドローピラジノーベンゾジアゼピン誘導体
JPH01104064A (ja) 塩基性に置換されたベンゾフランカルボン酸アミド、この化合物の製法及びこれを含有する医薬
CZ337295A3 (en) Naphthyridine derivatives, process of their preparation and pharmaceutical compositions containing thereof
EP0625514B1 (fr) Dérivés de 2-aminopyrazine-5-carboxamide, leur préparation et leur application en thérapeutique