ES8302682A1 - Un metodo de preparar derivados de fenil-piperazina - Google Patents
Un metodo de preparar derivados de fenil-piperazinaInfo
- Publication number
- ES8302682A1 ES8302682A1 ES505372A ES505372A ES8302682A1 ES 8302682 A1 ES8302682 A1 ES 8302682A1 ES 505372 A ES505372 A ES 505372A ES 505372 A ES505372 A ES 505372A ES 8302682 A1 ES8302682 A1 ES 8302682A1
- Authority
- ES
- Spain
- Prior art keywords
- piperazine derivatives
- phenyl piperazine
- antiagressive
- activity
- antiagressive activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN METODO PARA PREPARAR DERIVADOS DE FENIL-PIPERAZINA. SE HACE REACCIONAR EL COMPUESTO (I) CON EL CL<024>A<024>CO<024>NH<024>CO<024>R EN UN DISOLVENTE INERTE TAL COMO ETANOL O ACETONITRILO A UNA TEMPERATURA COMPRENDIDA ENTRE 20<025>C Y EL PUNTO DE EBULLICION DEL DISOLVENTE EMPLEADO, EN PRESENCIA DE UN CAPTADOR DE ACIDO. SE OBTIENE EL COMPUESTO (II) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES: R ES UN GRUPO TRIFLUOROMETILO O UN ATOMO DE HALOGENO. R ES UN GRUPO ALCOHILO O UN GRUPO ALCOXI, UN GRUPO CICLOALCOXILO TRIFLUOROMETILO, VINILO, NITRILO, FENILO, FENILO SUBSTITUIDO, UN GRUPO TIENILO, UN GRUPO PIRIDILO, UN GRUPO PIRIMIDILO U OTROS. TRATAMIENTO DEL COMPORTAMIENTO INTRAPUNITIVO Y EXTRAPUNITIVO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8005132A NL8005132A (nl) | 1980-09-12 | 1980-09-12 | Fenylpiperazinederivaten met antiagressieve werking. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES505372A0 ES505372A0 (es) | 1982-12-01 |
ES8302682A1 true ES8302682A1 (es) | 1982-12-01 |
Family
ID=19835869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505372A Expired ES8302682A1 (es) | 1980-09-12 | 1981-09-10 | Un metodo de preparar derivados de fenil-piperazina |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0048044A1 (es) |
JP (1) | JPS5781477A (es) |
AU (1) | AU7502881A (es) |
CA (1) | CA1158647A (es) |
CS (1) | CS228531B2 (es) |
DD (1) | DD202288A5 (es) |
DK (1) | DK399981A (es) |
ES (1) | ES8302682A1 (es) |
FI (1) | FI812807L (es) |
GR (1) | GR75818B (es) |
HU (1) | HU184965B (es) |
IL (1) | IL63783A0 (es) |
NL (1) | NL8005132A (es) |
PH (1) | PH17399A (es) |
PL (1) | PL232966A1 (es) |
YU (1) | YU217481A (es) |
ZA (1) | ZA816255B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK101683A (da) * | 1982-03-12 | 1983-09-13 | Duphar Int Res | Phenylpiperazinderivater og fremgangsmaade til fremstilling heraf |
US4477646A (en) * | 1983-08-24 | 1984-10-16 | The Dow Chemical Company | Piperazinoethyl ureas |
JP2641280B2 (ja) * | 1988-12-29 | 1997-08-13 | 日本ペイント株式会社 | 新規な環状ウレア誘導体 |
JPH0735363B2 (ja) * | 1990-07-03 | 1995-04-19 | 日本ペイント株式会社 | 不飽和カルバミン酸エステル類の製法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3824530A (en) * | 1972-12-05 | 1974-07-16 | Amp Inc | Installation of electrical connectors on wires intermediate the ends thereof |
-
1980
- 1980-09-12 NL NL8005132A patent/NL8005132A/nl not_active Application Discontinuation
-
1981
- 1981-08-25 EP EP81200928A patent/EP0048044A1/en not_active Ceased
- 1981-09-08 HU HU812581A patent/HU184965B/hu unknown
- 1981-09-08 AU AU75028/81A patent/AU7502881A/en not_active Abandoned
- 1981-09-09 DD DD81233163A patent/DD202288A5/de unknown
- 1981-09-09 IL IL63783A patent/IL63783A0/xx unknown
- 1981-09-09 YU YU02174/81A patent/YU217481A/xx unknown
- 1981-09-09 PL PL23296681A patent/PL232966A1/xx unknown
- 1981-09-09 CS CS816655A patent/CS228531B2/cs unknown
- 1981-09-09 DK DK399981A patent/DK399981A/da not_active Application Discontinuation
- 1981-09-09 GR GR66002A patent/GR75818B/el unknown
- 1981-09-09 JP JP56141149A patent/JPS5781477A/ja active Pending
- 1981-09-09 PH PH26171A patent/PH17399A/en unknown
- 1981-09-09 ZA ZA816255A patent/ZA816255B/xx unknown
- 1981-09-09 FI FI812807A patent/FI812807L/fi not_active Application Discontinuation
- 1981-09-10 ES ES505372A patent/ES8302682A1/es not_active Expired
- 1981-09-11 CA CA000385683A patent/CA1158647A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PH17399A (en) | 1984-08-08 |
JPS5781477A (en) | 1982-05-21 |
GR75818B (es) | 1984-08-02 |
NL8005132A (nl) | 1982-04-01 |
IL63783A0 (en) | 1981-12-31 |
FI812807L (fi) | 1982-03-13 |
ES505372A0 (es) | 1982-12-01 |
AU7502881A (en) | 1982-03-18 |
CS228531B2 (en) | 1984-05-14 |
CA1158647A (en) | 1983-12-13 |
DD202288A5 (de) | 1983-09-07 |
PL232966A1 (es) | 1982-10-25 |
ZA816255B (en) | 1983-04-27 |
EP0048044A1 (en) | 1982-03-24 |
HU184965B (en) | 1984-11-28 |
YU217481A (en) | 1983-09-30 |
DK399981A (da) | 1982-03-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8302681A1 (es) | Un metodo para preparar derivados de fenilpiperazina | |
JPS5665892A (en) | 6 betaahydroxyalkylpenicillaic acid derivative as betaalactamase inhibitor | |
ES8700851A1 (es) | Procedimiento para la obtencion de acido alquil-1- ciclopropil-1, 4-dihidro-4-oxo-3-quinolincarboxilico. | |
ES481729A1 (es) | Procedimiento para la preparacion de derivados de 1,2-dihi- droquinolein-2-onas. | |
BG41821A3 (en) | Method for preparing pyridyl derivatives | |
JPS56103168A (en) | Thiazole derivative, its preparation, and antihistaminic agent containing the same | |
ES8101550A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 2-pirrolidin-metanol. | |
ES8400752A1 (es) | "procedimiento para la preparacion de nuevos derivados de ciclofosfamida". | |
ES8404333A1 (es) | Un metodo para preparar derivados de fenilpiperazina. | |
ES8302682A1 (es) | Un metodo de preparar derivados de fenil-piperazina | |
FR2540870B1 (es) | ||
GB1479985A (en) | Cyclogeranoyl derivatives | |
PL255491A1 (en) | Agent for inhibition of pollen formation | |
ES8407322A1 (es) | Procedimiento para la preparacion de 7 -aciltio-15,16-metilen-3-oxo-17 -pregna-1,4-dien-21,17-carbolactonas | |
IL58925A (en) | Ovicidal compositions containing piperazine derivatives | |
ES8201531A1 (es) | Procedimiento de preparar alcoxi propanolaminas | |
ES8206550A1 (es) | Un procedimiento para la preparacion de derivados de 2-desoxi-3-5-di-o-alquilcarbonil-5-fluorurina. | |
ES8303372A1 (es) | Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida | |
GB1453490A (en) | Herbicidal thioesters | |
ES8605529A1 (es) | Procedimiento para la preparacion de acidos alfa-aminoal- quilfosfonicos y de acidos alfa-aminoalquilfosfinicos | |
ES8107002A1 (es) | Procedimiento de obtencion de compuestos herbicidas | |
ES505137A1 (es) | Procedimiento para la obtencion de n-oxiamidas | |
EP0103357A3 (en) | Substituted phenylpiperazine compounds suitable as antihypertensive agents, and processes for their production | |
ES8602031A1 (es) | Procedimiento de preparacion de derivados de nitrosoureas | |
DE3264330D1 (en) | Process for the preparation of cycloalkenon derivatives |