ES8303372A1 - Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida - Google Patents

Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida

Info

Publication number
ES8303372A1
ES8303372A1 ES506702A ES506702A ES8303372A1 ES 8303372 A1 ES8303372 A1 ES 8303372A1 ES 506702 A ES506702 A ES 506702A ES 506702 A ES506702 A ES 506702A ES 8303372 A1 ES8303372 A1 ES 8303372A1
Authority
ES
Spain
Prior art keywords
ones
phenyl
substituted
alkylthiazolidin
peptic ulcer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES506702A
Other languages
English (en)
Other versions
ES506702A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Publication of ES506702A0 publication Critical patent/ES506702A0/es
Publication of ES8303372A1 publication Critical patent/ES8303372A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS DE FENIL-5-ALQUITIAZOLIDINA-4-ONA, 2-SUBSTITUIDA, DE FORMULA DESARROLLADA (I), EN LA QUE R Y R SIGNIFICAN RESPECTIVAMENTE UN GRUPO ALQUILO INFERIOR DE UNO A TRES ATOMOS DE CARBONO, Y N REPRESENTA 1, 2 O 3. CONSISTE EN HACER REACCIONAR UN ALDEHIDO REPRESENTADO POR LA FORMULA (II), EN LA QUE R Y N TIENEN LOS SIGNIFICADOS YA INDICADOS, CON EL ACIDO 2-MERCAPTOPROPIONICO O CON UN ESTER DEL MISMO, EN PRESENCIA DE UN DISOLVENTE INERTE QUE CONTIENE UN COMPUESTO AMONICO, TAL COMO CARBONATO AMONICO. LA REACCION SE LLEVA A EFECTO A UNA TEMPERATURA COMPRENDIDA ENTRE 50 Y 150 GRADOS. DE APLICACION EN LA PREPARACION DE MEDICAMENTOS ANTI-ULCERA PEPTICA.
ES506702A 1980-10-09 1981-10-09 Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida Expired ES8303372A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55141239A JPS6052747B2 (ja) 1980-10-09 1980-10-09 2−置換フエニル−5−アルキルチアゾリジン−4−オン、及び該化合物有効成分とする抗消化性潰瘍剤

Publications (2)

Publication Number Publication Date
ES506702A0 ES506702A0 (es) 1983-02-01
ES8303372A1 true ES8303372A1 (es) 1983-02-01

Family

ID=15287329

Family Applications (1)

Application Number Title Priority Date Filing Date
ES506702A Expired ES8303372A1 (es) 1980-10-09 1981-10-09 Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida

Country Status (9)

Country Link
US (1) US4434172A (es)
EP (1) EP0050002B1 (es)
JP (1) JPS6052747B2 (es)
KR (1) KR860000059B1 (es)
CA (1) CA1167448A (es)
DE (1) DE3171323D1 (es)
ES (1) ES8303372A1 (es)
HU (1) HU182756B (es)
MX (2) MX7117E (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1154447A (en) * 1979-07-09 1983-09-27 Takao Kawasaki 2-substituted-4-thiazolidones
EP0206318B1 (en) * 1985-06-25 1990-04-11 Ishihara Sangyo Kaisha, Ltd. Organophosphorus compounds, process for their preparation and insecticidal, miticidal, nematicidal or soil pesticidal compositions containing them
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity
JPH0479620A (ja) * 1990-07-20 1992-03-13 Matsushita Electric Ind Co Ltd コードレス電話装置
JPH0553058U (ja) * 1991-12-24 1993-07-13 株式会社フジクラ 絶縁ケーブル

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2623048A (en) 1948-04-05 1952-12-23 Parke Davis & Co 4-thiazolidone derivatives and process for preparing the same
US3270027A (en) 1963-10-15 1966-08-30 Sterling Drug Inc 2-trichloromethyl-4-thiazolidones
GB1345159A (en) 1970-06-26 1974-01-30 Ici Ltd Oxathiolanone and thiazolidinone derivatives
GB1428390A (en) 1972-08-18 1976-03-17 Ici Ltd Thiazolidinones
US4053471A (en) 1976-11-11 1977-10-11 E. R. Squibb & Sons, Inc. 4-thiazolidinone derivatives
CA1154447A (en) * 1979-07-09 1983-09-27 Takao Kawasaki 2-substituted-4-thiazolidones

Also Published As

Publication number Publication date
EP0050002A1 (en) 1982-04-21
ES506702A0 (es) 1983-02-01
JPS5764683A (en) 1982-04-19
KR860000059B1 (ko) 1986-02-06
JPS6052747B2 (ja) 1985-11-21
MX9015A (es) 1993-12-01
US4434172A (en) 1984-02-28
CA1167448A (en) 1984-05-15
EP0050002B1 (en) 1985-07-10
DE3171323D1 (en) 1985-08-14
HU182756B (en) 1984-03-28
MX7117E (es) 1987-06-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603