CS228133B2 - Production method of nonpeptide and decapeptide derivative of hormone releasing luteinizae hormone - Google Patents

Production method of nonpeptide and decapeptide derivative of hormone releasing luteinizae hormone Download PDF

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Publication number
CS228133B2
CS228133B2 CS804093A CS409380A CS228133B2 CS 228133 B2 CS228133 B2 CS 228133B2 CS 804093 A CS804093 A CS 804093A CS 409380 A CS409380 A CS 409380A CS 228133 B2 CS228133 B2 CS 228133B2
Authority
CS
Czechoslovakia
Prior art keywords
naphthyl
group
alanyl
acid
pyro
Prior art date
Application number
CS804093A
Other languages
Czech (cs)
English (en)
Inventor
John J Nestor
Gordon H Jones
Brian H Vickery
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority claimed from US06/047,661 external-priority patent/US4234571A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of CS228133B2 publication Critical patent/CS228133B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CS804093A 1979-06-11 1980-06-10 Production method of nonpeptide and decapeptide derivative of hormone releasing luteinizae hormone CS228133B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/047,661 US4234571A (en) 1979-06-11 1979-06-11 Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
FR7927754A FR2458538A1 (fr) 1979-06-11 1979-11-09 Derives nonapeptidiques et decapeptidiques de l'hormone liberant l'hormone luteinisante, leur procede de production et composition pharmaceutique les contenant

Publications (1)

Publication Number Publication Date
CS228133B2 true CS228133B2 (en) 1984-05-14

Family

ID=26221428

Family Applications (1)

Application Number Title Priority Date Filing Date
CS804093A CS228133B2 (en) 1979-06-11 1980-06-10 Production method of nonpeptide and decapeptide derivative of hormone releasing luteinizae hormone

Country Status (22)

Country Link
EP (1) EP0021234B1 (de)
AU (1) AU539495B2 (de)
CA (1) CA1157851A (de)
CS (1) CS228133B2 (de)
DD (1) DD152542A5 (de)
DE (3) DE19375028I2 (de)
DK (2) DK149046C (de)
ES (1) ES8104201A1 (de)
FI (1) FI72527C (de)
GB (1) GB2054603B (de)
GR (1) GR69259B (de)
HK (1) HK17486A (de)
IE (1) IE49946B1 (de)
IL (1) IL60282A (de)
IT (1) IT1149971B (de)
MY (1) MY8600324A (de)
NL (1) NL930103I2 (de)
NO (1) NO151896C (de)
NZ (1) NZ193984A (de)
PL (1) PL126655B1 (de)
PT (1) PT71366A (de)
YU (2) YU42217B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318905A (en) * 1980-06-23 1982-03-09 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues
ZA815447B (en) * 1980-08-29 1982-08-25 Salk Inst For Biological Studi Peptides affecting gonadal function
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
CS230614B1 (en) * 1982-08-06 1984-08-13 Martin Cs Flegel Analogues of realising factor for luteining and folliculstimulated hormon
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
EP0206807A3 (de) * 1985-06-28 1988-01-20 Kissei Pharmaceutical Co. Ltd. Aminosäure-Derivate
US4761398A (en) * 1986-08-18 1988-08-02 Embrex, Inc. Method of inducing birds to molt
US4851211A (en) * 1986-11-25 1989-07-25 Abbott Laboratories LHRH analog formulations
US5028430A (en) * 1987-05-08 1991-07-02 Syntex (U.S.A.) Inc. Delivery systems for the controlled administration of LHRH analogs
ES2108684T3 (es) * 1988-02-10 1998-01-01 Tap Pharmaceuticals Inc Analogo de la hormona de liberacion de la hormona luteinizante (lhrh).
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
US6353030B1 (en) 1990-08-01 2002-03-05 Novartis Ag Relating to organic compounds
JP2944419B2 (ja) * 1993-05-10 1999-09-06 ノバルティス アクチエンゲゼルシャフト 持続性遊離組成物中の薬理学的活性成分の安定
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
US6239108B1 (en) 1996-07-11 2001-05-29 Biogen, Inc. Cell adhesion inhibitors
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
DK0914605T3 (da) 1996-07-25 2007-09-10 Biogen Idec Inc Molekylemodel for VLA-4-inhibitorer
PL198189B1 (pl) 1998-05-28 2008-06-30 Biogen Idec Ma (R)-N-{[4-{[(2-metylofenyloamino)-karbonylo]amino}fenylo]acetylo}-L-prolilo-3-metylo]-ß-alanina, jej zastosowanie i kompozycja farmaceutyczna ją zawierająca
JP2003506491A (ja) 1999-08-13 2003-02-18 バイオジェン インコーポレイテッド 細胞接着インヒビター
US6875743B1 (en) 2000-11-28 2005-04-05 Biogen, Inc. Cell adhesion inhibitors
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
RU2604166C2 (ru) 2012-06-22 2016-12-10 Ф.Хоффманн-Ля Рош Аг Способ и устройство для определения аналита в физиологической жидкости
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50142563A (de) * 1974-04-26 1975-11-17
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2617646C2 (de) * 1976-04-22 1986-07-31 Hoechst Ag, 6230 Frankfurt Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
IT1149971B (it) 1986-12-10
NZ193984A (en) 1982-09-07
GB2054603B (en) 1983-02-09
NL930103I2 (nl) 1997-05-01
DK79384D0 (da) 1984-02-20
IT8022519A0 (it) 1980-06-03
DK149046C (da) 1986-08-18
HK17486A (en) 1986-03-21
CA1157851A (en) 1983-11-29
PL224852A1 (de) 1981-03-27
YU46315B (sh) 1993-05-28
DK152734C (da) 1988-10-10
MY8600324A (en) 1986-12-31
DK149046B (da) 1985-12-30
NO151896C (no) 1985-06-26
YU82387A (en) 1988-04-30
DK79384A (da) 1984-02-20
DE3069013D1 (en) 1984-09-27
DD152542A5 (de) 1981-12-02
GR69259B (de) 1982-05-12
FI72527C (fi) 1987-06-08
YU42217B (en) 1988-06-30
AU539495B2 (en) 1984-10-04
AU5917680A (en) 1980-12-18
IL60282A (en) 1983-09-30
ES492289A0 (es) 1981-04-01
ES8104201A1 (es) 1981-04-01
EP0021234B1 (de) 1984-08-22
YU155380A (en) 1984-02-29
FI72527B (fi) 1987-02-27
PT71366A (en) 1980-07-01
FI801856A (fi) 1980-12-12
NO151896B (no) 1985-03-18
DK152734B (da) 1988-05-02
DE19375028I2 (de) 2000-12-07
DK248880A (da) 1980-12-12
PL126655B1 (en) 1983-08-31
GB2054603A (en) 1981-02-18
NL930103I1 (nl) 1993-10-01
IE49946B1 (en) 1986-01-22
IL60282A0 (en) 1980-09-16
EP0021234A1 (de) 1981-01-07
NO801729L (no) 1980-12-12
DE3021736A1 (de) 1980-12-18
IE801193L (en) 1980-12-11

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