CS224637B2 - Method for producing improved cephaelosporine - Google Patents

Method for producing improved cephaelosporine Download PDF

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Publication number
CS224637B2
CS224637B2 CS819179A CS917981A CS224637B2 CS 224637 B2 CS224637 B2 CS 224637B2 CS 819179 A CS819179 A CS 819179A CS 917981 A CS917981 A CS 917981A CS 224637 B2 CS224637 B2 CS 224637B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
group
compounds
acid
defined above
Prior art date
Application number
CS819179A
Other languages
Czech (cs)
English (en)
Inventor
Bernd Dr Wetzel
Eberhard Dr Woitun
Wolfgang Dr Rauter
Roland Dr Maier
Uwe Dr Lechner
Hanns Dr Goeth
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CS224637B2 publication Critical patent/CS224637B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS819179A 1980-12-13 1981-12-10 Method for producing improved cephaelosporine CS224637B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803047082 DE3047082A1 (de) 1980-12-13 1980-12-13 Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
CS224637B2 true CS224637B2 (en) 1984-01-16

Family

ID=6119125

Family Applications (1)

Application Number Title Priority Date Filing Date
CS819179A CS224637B2 (en) 1980-12-13 1981-12-10 Method for producing improved cephaelosporine

Country Status (23)

Country Link
US (1) US4401667A (el)
EP (1) EP0054677B1 (el)
JP (1) JPS57123192A (el)
AR (1) AR229804A1 (el)
AT (1) ATE13536T1 (el)
AU (1) AU7814881A (el)
CA (1) CA1170652A (el)
CS (1) CS224637B2 (el)
DD (1) DD201905A5 (el)
DE (2) DE3047082A1 (el)
DK (1) DK542081A (el)
ES (3) ES8302006A1 (el)
FI (1) FI813992L (el)
GB (1) GB2089346B (el)
GR (1) GR76948B (el)
HU (1) HU186448B (el)
IL (1) IL64427A (el)
NO (1) NO814240L (el)
NZ (1) NZ199129A (el)
PL (1) PL129917B1 (el)
PT (1) PT74117B (el)
SU (1) SU1075977A3 (el)
ZA (1) ZA818317B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
FR2816309B1 (fr) * 2000-11-09 2002-12-27 Bioprojet Soc Civ Procede de synthese de derives n-(mercaptoacyl)-amino-acides a partir d'acides acryliques alpha-substitues

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5344585A (en) * 1976-10-02 1978-04-21 Meiji Seika Kaisha Ltd Cephalosporin derivatives and their preparation
US4311699A (en) * 1979-03-12 1982-01-19 Haskell Theodore H Aminoacid derivatives of cephalosporin compounds
DE2924948A1 (de) * 1979-06-21 1981-01-22 Thomae Gmbh Dr K Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0053276A3 (de) * 1980-12-02 1983-08-03 Dr. Karl Thomae GmbH Neue Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
US4401667A (en) 1983-08-30
ATE13536T1 (de) 1985-06-15
ES507829A0 (es) 1983-01-01
GB2089346A (en) 1982-06-23
ES8302006A1 (es) 1983-01-01
HU186448B (en) 1985-07-29
NO814240L (no) 1982-06-14
EP0054677A3 (en) 1983-07-06
IL64427A (en) 1984-10-31
NZ199129A (en) 1985-02-28
PT74117A (de) 1982-01-01
DE3047082A1 (de) 1982-07-29
CA1170652A (en) 1984-07-10
SU1075977A3 (ru) 1984-02-23
ES8304996A1 (es) 1983-03-16
AR229804A1 (es) 1983-11-30
DE3170755D1 (en) 1985-07-04
ES513020A0 (es) 1983-03-16
JPS57123192A (en) 1982-07-31
GR76948B (el) 1984-09-04
ZA818317B (en) 1983-08-31
FI813992L (fi) 1982-06-14
PT74117B (de) 1983-12-19
EP0054677A2 (de) 1982-06-30
PL129917B1 (en) 1984-06-30
ES513019A0 (es) 1983-03-16
DK542081A (da) 1982-06-14
GB2089346B (en) 1984-08-15
PL234192A1 (en) 1983-03-14
DD201905A5 (de) 1983-08-17
ES8304995A1 (es) 1983-03-16
AU7814881A (en) 1982-06-24
IL64427A0 (en) 1982-03-31
EP0054677B1 (de) 1985-05-29

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