CS214796B2 - Method of making the new derivatives of 4-amino-2-piperidinochinazoline - Google Patents

Method of making the new derivatives of 4-amino-2-piperidinochinazoline Download PDF

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Publication number
CS214796B2
CS214796B2 CS793372A CS337279A CS214796B2 CS 214796 B2 CS214796 B2 CS 214796B2 CS 793372 A CS793372 A CS 793372A CS 337279 A CS337279 A CS 337279A CS 214796 B2 CS214796 B2 CS 214796B2
Authority
CS
Czechoslovakia
Prior art keywords
preparation
piperidine
phenyl
lower alkyl
pharmaceutically acceptable
Prior art date
Application number
CS793372A
Other languages
Czech (cs)
English (en)
Inventor
Simon F Campbell
John Ch Danilewicz
Colin W Greengrass
Rhona M Plews
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS803910A priority Critical patent/CS214797B2/cs
Publication of CS214796B2 publication Critical patent/CS214796B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CS793372A 1978-05-18 1979-05-16 Method of making the new derivatives of 4-amino-2-piperidinochinazoline CS214796B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS803910A CS214797B2 (cs) 1978-05-18 1980-06-03 Způsob výroby nových derivátů 4-amino-2-piperidinochinazolinu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2035178 1978-05-18

Publications (1)

Publication Number Publication Date
CS214796B2 true CS214796B2 (en) 1982-05-28

Family

ID=10144517

Family Applications (1)

Application Number Title Priority Date Filing Date
CS793372A CS214796B2 (en) 1978-05-18 1979-05-16 Method of making the new derivatives of 4-amino-2-piperidinochinazoline

Country Status (30)

Country Link
US (1) US4243666A (fr)
JP (1) JPS554370A (fr)
AR (2) AR223487A1 (fr)
AT (1) ATA363379A (fr)
AU (1) AU512947B2 (fr)
BE (1) BE876297A (fr)
CA (1) CA1240325A (fr)
CH (1) CH643553A5 (fr)
CS (1) CS214796B2 (fr)
DD (1) DD143613A5 (fr)
DE (1) DE2919800A1 (fr)
DK (1) DK159079A (fr)
ES (2) ES480671A1 (fr)
FI (1) FI64589C (fr)
FR (1) FR2434162A1 (fr)
GR (1) GR72824B (fr)
HU (1) HU182562B (fr)
IL (1) IL57297A (fr)
IN (1) IN153045B (fr)
IT (1) IT1114222B (fr)
LU (1) LU81284A1 (fr)
NL (1) NL172157C (fr)
NO (1) NO791648L (fr)
NZ (1) NZ190465A (fr)
PH (1) PH14802A (fr)
PL (2) PL121158B1 (fr)
PT (1) PT69622A (fr)
SE (1) SE439306B (fr)
YU (2) YU115279A (fr)
ZA (1) ZA792390B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4607034A (en) * 1979-10-29 1986-08-19 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinazoline derivatives and pharmaceutical composition thereof
JPS5962766U (ja) * 1982-06-30 1984-04-25 守田　智 小動物用給水器
GB8414518D0 (en) * 1984-06-07 1984-07-11 Pfizer Ltd Therapeutic agents
US5801195A (en) * 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
US6248888B1 (en) 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
CN1494529A (zh) * 2001-01-18 2004-05-05 武田药品工业株式会社 苄基哌啶化合物的制备方法
US6746460B2 (en) * 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
WO2005042501A1 (fr) * 2003-11-03 2005-05-12 Warner-Lambert Company Llc Nouveaux inhibiteurs du recaptage de la norepinephrine pour le traitement des troubles du systeme nerveux central
WO2008045564A2 (fr) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Composés de carboxamide et leur utilisation
KR101441930B1 (ko) * 2007-04-04 2014-09-19 시플라 리미티드 에르로티닙 및 그의 약학적으로 허용가능한 염의 제조방법
RU2010128543A (ru) 2007-12-11 2012-01-20 Сайтопатфайндер, Инк. (Jp) Карбоксамидные соединения и их применение в качестве агонистов хемокиновых рецепторов
AU2009315761A1 (en) * 2008-11-14 2010-05-20 F. Hoffmann-La Roche Ag Quinazoline derivatives as NK3 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
FR2321890A1 (fr) * 1975-08-26 1977-03-25 Synthelabo Nouveaux derives de la quinazoline, leurs sels, leur preparation et les medicaments qui en renferment
DK140695C (da) * 1976-05-07 1980-05-12 Synthelabo Analogifremgangsmaade til fremstilling af 2,4-diamino-6,7-dimethoxyquinazolinderivater eller syreadditionssalte heraf

Also Published As

Publication number Publication date
NZ190465A (en) 1981-05-01
IL57297A0 (en) 1979-09-30
AR223487A1 (es) 1981-08-31
PH14802A (en) 1981-12-14
SE439306B (sv) 1985-06-10
DK159079A (da) 1979-11-19
HU182562B (en) 1984-02-28
ZA792390B (en) 1980-07-30
PL120651B1 (en) 1982-03-31
NL172157C (nl) 1983-07-18
CA1240325A (fr) 1988-08-09
YU115279A (en) 1983-04-30
AU512947B2 (en) 1980-11-06
BE876297A (fr) 1979-11-16
US4243666A (en) 1981-01-06
PL223844A1 (fr) 1981-01-02
IT7922720A0 (it) 1979-05-16
ATA363379A (de) 1983-05-15
PL121158B1 (en) 1982-04-30
GR72824B (fr) 1983-12-06
IN153045B (fr) 1984-05-26
ES488210A0 (es) 1980-12-16
NL172157B (nl) 1983-02-16
PL215626A1 (fr) 1980-08-25
YU256382A (en) 1983-04-30
FI791562A (fi) 1979-11-19
JPS5623992B2 (fr) 1981-06-03
CH643553A5 (de) 1984-06-15
FI64589B (fi) 1983-08-31
DD143613A5 (de) 1980-09-03
FR2434162B1 (fr) 1983-04-22
DE2919800A1 (de) 1979-11-22
FR2434162A1 (fr) 1980-03-21
AR224784A1 (es) 1982-01-15
AU4710179A (en) 1979-11-22
NO791648L (no) 1979-11-20
FI64589C (fi) 1983-12-12
SE7904358L (sv) 1979-11-19
ES480671A1 (es) 1980-08-16
IT1114222B (it) 1986-01-27
NL7903853A (nl) 1979-11-20
IL57297A (en) 1983-02-23
JPS554370A (en) 1980-01-12
LU81284A1 (fr) 1980-12-16
ES8101584A1 (es) 1980-12-16
PT69622A (en) 1979-06-01

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