CS213377B2 - Method of making the derivatives of 6-acylaminotetrahydro-1,3,5-triazin-2,4-dion - Google Patents

Method of making the derivatives of 6-acylaminotetrahydro-1,3,5-triazin-2,4-dion Download PDF

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Publication number
CS213377B2
CS213377B2 CS793623A CS362379A CS213377B2 CS 213377 B2 CS213377 B2 CS 213377B2 CS 793623 A CS793623 A CS 793623A CS 362379 A CS362379 A CS 362379A CS 213377 B2 CS213377 B2 CS 213377B2
Authority
CS
Czechoslovakia
Prior art keywords
group
alkyl
phenyl
formula
pharmaceutically acceptable
Prior art date
Application number
CS793623A
Other languages
Czech (cs)
English (en)
Inventor
Edward D Brown
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Priority to CS804527A priority Critical patent/CS213378B2/cs
Publication of CS213377B2 publication Critical patent/CS213377B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/38—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/42—One nitrogen atom
    • C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CS793623A 1978-05-26 1979-05-25 Method of making the derivatives of 6-acylaminotetrahydro-1,3,5-triazin-2,4-dion CS213377B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS804527A CS213378B2 (cs) 1978-05-26 1980-06-25 Způsob výroby derivátů B-acylaminotetrabydro-l,3,3-triazin-2,4-dionu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2293878 1978-05-26

Publications (1)

Publication Number Publication Date
CS213377B2 true CS213377B2 (en) 1982-04-09

Family

ID=10187501

Family Applications (1)

Application Number Title Priority Date Filing Date
CS793623A CS213377B2 (en) 1978-05-26 1979-05-25 Method of making the derivatives of 6-acylaminotetrahydro-1,3,5-triazin-2,4-dion

Country Status (24)

Country Link
US (1) US4254122A (pt)
EP (1) EP0005911B1 (pt)
JP (1) JPS54154779A (pt)
AT (1) ATE698T1 (pt)
AU (1) AU529948B2 (pt)
CA (1) CA1108138A (pt)
CS (1) CS213377B2 (pt)
DD (1) DD143906A5 (pt)
DE (1) DE2962124D1 (pt)
DK (1) DK213179A (pt)
ES (1) ES480932A1 (pt)
FI (1) FI66180C (pt)
GR (1) GR68185B (pt)
HU (1) HU180252B (pt)
IE (1) IE49170B1 (pt)
IL (1) IL57324A (pt)
MW (1) MW1379A1 (pt)
NO (1) NO791722L (pt)
NZ (1) NZ190402A (pt)
PH (1) PH14793A (pt)
PT (1) PT69650A (pt)
ZA (1) ZA792247B (pt)
ZM (1) ZM4579A1 (pt)
ZW (1) ZW9179A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
AU7080298A (en) * 1997-04-25 1998-11-24 Takeda Chemical Industries Ltd. Triazine derivatives, their production and agrochemical composition
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
JP2005532295A (ja) * 2002-04-17 2005-10-27 メディカル リサーチ カウンシル 月経過多を治療するためのＦＰレセプターアンタゴニスト又はＰＧＦ２αアンタゴニスト
CA2533846C (en) * 2003-07-29 2012-08-28 Universitaetsklinikum Muenster Means and methods for treating a disease which is associated with an excess transport of hyaluronan across a lipid bilayer
US7199156B2 (en) * 2003-10-10 2007-04-03 Milos Chvapil Composition and method to treat solid tumors
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
WO2007139753A2 (en) * 2006-05-22 2007-12-06 Combinatorx, Incorporated Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels
WO2009038708A1 (en) * 2007-09-19 2009-03-26 Combinatorx, Incorporated Therapeutic regimens for the treatment of immunoinflammatory disorders
CN101938996A (zh) * 2007-12-17 2011-01-05 康宾纳特克斯公司 用于治疗免疫炎症性紊乱的治疗方案
PL2399910T3 (pl) * 2009-02-13 2014-09-30 Shionogi & Co Pochodne triazyny jako antagoniści receptora p2x3 i/albo p2x2/3 i kompozycja farmaceutyczna zawierająca je
US9212130B2 (en) 2010-08-10 2015-12-15 Shionogi & Co., Ltd. Heterocyclic derivative and pharmaceutical composition comprising the same
RU2565073C2 (ru) * 2010-08-10 2015-10-20 Сионоги Энд Ко., Лтд. Триазиновое производное и включающая его фармацевтическая композиция, обладающая анальгетической активностью
JP6124351B2 (ja) 2012-02-09 2017-05-10 塩野義製薬株式会社 複素環および炭素環誘導体
TWI637949B (zh) 2013-06-14 2018-10-11 塩野義製藥股份有限公司 胺基三衍生物及含有其等之醫藥組合物
WO2022162689A1 (en) * 2021-01-26 2022-08-04 Council Of Scientific And Industrial Research Triazine-based self-assembling system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983116A (en) * 1973-04-05 1976-09-28 E. I. Du Pont De Nemours And Company Herbicidal triazines
US4035365A (en) * 1973-11-01 1977-07-12 Imperial Chemical Industries Limited Triazinediones
GB1543037A (en) * 1975-02-05 1979-03-28 Ici Ltd Selective herbicidal triazine-diones
GB1464248A (en) 1973-11-01 1977-02-09 Ici Ltd Substituted triazinediones their preparation and use as herbicides
US4082536A (en) * 1973-11-01 1978-04-04 Imperial Chemical Industries Limited Heterocyclic compounds and their use as pesticides
GB1504304A (en) * 1974-02-15 1978-03-15 Ici Ltd Process of combating fungal and bacterial infections of plants with triazine dione derivatives
GB1599518A (en) * 1977-02-21 1981-10-07 Ici Ltd 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ZM4579A1 (en) 1981-05-21
PT69650A (en) 1979-06-01
AU4694979A (en) 1979-11-29
DE2962124D1 (en) 1982-03-25
DK213179A (da) 1979-11-27
IE49170B1 (en) 1985-08-21
AU529948B2 (en) 1983-06-30
ES480932A1 (es) 1980-02-01
GR68185B (pt) 1981-11-09
US4254122A (en) 1981-03-03
NO791722L (no) 1979-11-27
NZ190402A (en) 1982-05-31
MW1379A1 (en) 1981-04-08
FI66180B (fi) 1984-05-31
CA1108138A (en) 1981-09-01
EP0005911B1 (en) 1982-02-17
FI66180C (fi) 1984-09-10
JPS54154779A (en) 1979-12-06
ATE698T1 (de) 1982-03-15
IL57324A (en) 1983-10-31
PH14793A (en) 1981-12-09
ZA792247B (en) 1980-05-28
EP0005911A1 (en) 1979-12-12
FI791670A (fi) 1979-11-27
IE790889L (en) 1979-11-26
ZW9179A1 (en) 1981-01-21
IL57324A0 (en) 1979-09-30
DD143906A5 (de) 1980-09-17
HU180252B (en) 1983-02-28

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