DE2962124D1 - Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture - Google Patents

Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture

Info

Publication number
DE2962124D1
DE2962124D1 DE7979300756T DE2962124T DE2962124D1 DE 2962124 D1 DE2962124 D1 DE 2962124D1 DE 7979300756 T DE7979300756 T DE 7979300756T DE 2962124 T DE2962124 T DE 2962124T DE 2962124 D1 DE2962124 D1 DE 2962124D1
Authority
DE
Germany
Prior art keywords
alkyl
radical
manufacture
pharmaceutical compositions
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979300756T
Other languages
English (en)
Inventor
Edward Douglas Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of DE2962124D1 publication Critical patent/DE2962124D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/38Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/42One nitrogen atom
    • C07D251/46One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
DE7979300756T 1978-05-26 1979-05-02 Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture Expired DE2962124D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2293878 1978-05-26

Publications (1)

Publication Number Publication Date
DE2962124D1 true DE2962124D1 (en) 1982-03-25

Family

ID=10187501

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979300756T Expired DE2962124D1 (en) 1978-05-26 1979-05-02 Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture

Country Status (24)

Country Link
US (1) US4254122A (de)
EP (1) EP0005911B1 (de)
JP (1) JPS54154779A (de)
AT (1) ATE698T1 (de)
AU (1) AU529948B2 (de)
CA (1) CA1108138A (de)
CS (1) CS213377B2 (de)
DD (1) DD143906A5 (de)
DE (1) DE2962124D1 (de)
DK (1) DK213179A (de)
ES (1) ES480932A1 (de)
FI (1) FI66180C (de)
GR (1) GR68185B (de)
HU (1) HU180252B (de)
IE (1) IE49170B1 (de)
IL (1) IL57324A (de)
MW (1) MW1379A1 (de)
NO (1) NO791722L (de)
NZ (1) NZ190402A (de)
PH (1) PH14793A (de)
PT (1) PT69650A (de)
ZA (1) ZA792247B (de)
ZM (1) ZM4579A1 (de)
ZW (1) ZW9179A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
AU7080298A (en) * 1997-04-25 1998-11-24 Takeda Chemical Industries Ltd. Triazine derivatives, their production and agrochemical composition
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
JP2005532295A (ja) * 2002-04-17 2005-10-27 メディカル リサーチ カウンシル 月経過多を治療するためのFPレセプターアンタゴニスト又はPGF2αアンタゴニスト
US20080152640A1 (en) * 2003-07-29 2008-06-26 Peter Prehm Means and Methods For Treating a Disease Which is Associated With an Excess Transport of Hyaluronan Across a Lipid Bilayer
US7199156B2 (en) * 2003-10-10 2007-04-03 Milos Chvapil Composition and method to treat solid tumors
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
MX2008014828A (es) * 2006-05-22 2009-02-06 Combinatorx Inc Metodos y composiciones para el tratamiento de enfermedades o condiciones asociadas con niveles incrementados de proteina c-reactiva, interleucina-6 o interferon-gamma.
US20090075955A1 (en) * 2007-09-19 2009-03-19 Combinatorx, Inc. Therapeutic regimens for the treatment of immunoinflammatory disorders
MX2010006724A (es) * 2007-12-17 2010-09-07 Combinatorx Inc Regimenes terapeuticos para el tratamiento de desordenes inmunoinflamatorios.
CN102395571B (zh) * 2009-02-13 2015-12-16 盐野义制药株式会社 三嗪衍生物及含有该三嗪衍生物的药物组合物
EP2604595B1 (de) * 2010-08-10 2016-03-16 Shionogi&Co., Ltd. Triazinderivat und pharmazeutische schmerzmittelverbindung damit
WO2012020742A1 (ja) 2010-08-10 2012-02-16 塩野義製薬株式会社 新規複素環誘導体およびそれらを含有する医薬組成物
WO2013118855A1 (ja) 2012-02-09 2013-08-15 塩野義製薬株式会社 複素環および炭素環誘導体
TWI637949B (zh) 2013-06-14 2018-10-11 塩野義製藥股份有限公司 胺基三衍生物及含有其等之醫藥組合物
WO2022162689A1 (en) * 2021-01-26 2022-08-04 Council Of Scientific And Industrial Research Triazine-based self-assembling system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983116A (en) * 1973-04-05 1976-09-28 E. I. Du Pont De Nemours And Company Herbicidal triazines
US4035365A (en) * 1973-11-01 1977-07-12 Imperial Chemical Industries Limited Triazinediones
GB1543037A (en) * 1975-02-05 1979-03-28 Ici Ltd Selective herbicidal triazine-diones
US4082536A (en) * 1973-11-01 1978-04-04 Imperial Chemical Industries Limited Heterocyclic compounds and their use as pesticides
GB1464248A (en) 1973-11-01 1977-02-09 Ici Ltd Substituted triazinediones their preparation and use as herbicides
GB1504304A (en) * 1974-02-15 1978-03-15 Ici Ltd Process of combating fungal and bacterial infections of plants with triazine dione derivatives
GB1599518A (en) * 1977-02-21 1981-10-07 Ici Ltd 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
EP0005911A1 (de) 1979-12-12
IL57324A0 (en) 1979-09-30
ZW9179A1 (en) 1981-01-21
FI66180B (fi) 1984-05-31
NZ190402A (en) 1982-05-31
AU4694979A (en) 1979-11-29
FI66180C (fi) 1984-09-10
ES480932A1 (es) 1980-02-01
ZA792247B (en) 1980-05-28
IL57324A (en) 1983-10-31
CA1108138A (en) 1981-09-01
PH14793A (en) 1981-12-09
MW1379A1 (en) 1981-04-08
NO791722L (no) 1979-11-27
US4254122A (en) 1981-03-03
DD143906A5 (de) 1980-09-17
DK213179A (da) 1979-11-27
IE790889L (en) 1979-11-26
IE49170B1 (en) 1985-08-21
AU529948B2 (en) 1983-06-30
PT69650A (en) 1979-06-01
JPS54154779A (en) 1979-12-06
FI791670A (fi) 1979-11-27
ATE698T1 (de) 1982-03-15
EP0005911B1 (de) 1982-02-17
HU180252B (en) 1983-02-28
GR68185B (de) 1981-11-09
CS213377B2 (en) 1982-04-09
ZM4579A1 (en) 1981-05-21

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee