FI66180C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6-acylaminotetrahydro-1,3,5-triazin-2,4-dioner - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6-acylaminotetrahydro-1,3,5-triazin-2,4-dioner Download PDF

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Publication number
FI66180C
FI66180C FI791670A FI791670A FI66180C FI 66180 C FI66180 C FI 66180C FI 791670 A FI791670 A FI 791670A FI 791670 A FI791670 A FI 791670A FI 66180 C FI66180 C FI 66180C
Authority
FI
Finland
Prior art keywords
phenyl
alkyl
radical
formula
methyl
Prior art date
Application number
FI791670A
Other languages
English (en)
Finnish (fi)
Other versions
FI66180B (fi
FI791670A (fi
Inventor
Edward Douglas Brown
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of FI791670A publication Critical patent/FI791670A/fi
Publication of FI66180B publication Critical patent/FI66180B/fi
Application granted granted Critical
Publication of FI66180C publication Critical patent/FI66180C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/38Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/42One nitrogen atom
    • C07D251/46One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
FI791670A 1978-05-26 1979-05-25 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6-acylaminotetrahydro-1,3,5-triazin-2,4-dioner FI66180C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2293878 1978-05-26
GB2293878 1978-05-26

Publications (3)

Publication Number Publication Date
FI791670A FI791670A (fi) 1979-11-27
FI66180B FI66180B (fi) 1984-05-31
FI66180C true FI66180C (fi) 1984-09-10

Family

ID=10187501

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791670A FI66180C (fi) 1978-05-26 1979-05-25 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6-acylaminotetrahydro-1,3,5-triazin-2,4-dioner

Country Status (24)

Country Link
US (1) US4254122A (de)
EP (1) EP0005911B1 (de)
JP (1) JPS54154779A (de)
AT (1) ATE698T1 (de)
AU (1) AU529948B2 (de)
CA (1) CA1108138A (de)
CS (1) CS213377B2 (de)
DD (1) DD143906A5 (de)
DE (1) DE2962124D1 (de)
DK (1) DK213179A (de)
ES (1) ES480932A1 (de)
FI (1) FI66180C (de)
GR (1) GR68185B (de)
HU (1) HU180252B (de)
IE (1) IE49170B1 (de)
IL (1) IL57324A (de)
MW (1) MW1379A1 (de)
NO (1) NO791722L (de)
NZ (1) NZ190402A (de)
PH (1) PH14793A (de)
PT (1) PT69650A (de)
ZA (1) ZA792247B (de)
ZM (1) ZM4579A1 (de)
ZW (1) ZW9179A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8629567D0 (en) * 1986-12-10 1987-01-21 Boots Co Plc Therapeutic agents
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
AU7080298A (en) * 1997-04-25 1998-11-24 Takeda Chemical Industries Ltd. Triazine derivatives, their production and agrochemical composition
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
JP2005532295A (ja) * 2002-04-17 2005-10-27 メディカル リサーチ カウンシル 月経過多を治療するためのFPレセプターアンタゴニスト又はPGF2αアンタゴニスト
CA2533846C (en) * 2003-07-29 2012-08-28 Universitaetsklinikum Muenster Means and methods for treating a disease which is associated with an excess transport of hyaluronan across a lipid bilayer
US7199156B2 (en) * 2003-10-10 2007-04-03 Milos Chvapil Composition and method to treat solid tumors
TW200517114A (en) * 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
WO2007139753A2 (en) * 2006-05-22 2007-12-06 Combinatorx, Incorporated Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels
WO2009038708A1 (en) * 2007-09-19 2009-03-26 Combinatorx, Incorporated Therapeutic regimens for the treatment of immunoinflammatory disorders
CN101938996A (zh) * 2007-12-17 2011-01-05 康宾纳特克斯公司 用于治疗免疫炎症性紊乱的治疗方案
PL2399910T3 (pl) * 2009-02-13 2014-09-30 Shionogi & Co Pochodne triazyny jako antagoniści receptora p2x3 i/albo p2x2/3 i kompozycja farmaceutyczna zawierająca je
US9212130B2 (en) 2010-08-10 2015-12-15 Shionogi & Co., Ltd. Heterocyclic derivative and pharmaceutical composition comprising the same
RU2565073C2 (ru) * 2010-08-10 2015-10-20 Сионоги Энд Ко., Лтд. Триазиновое производное и включающая его фармацевтическая композиция, обладающая анальгетической активностью
JP6124351B2 (ja) 2012-02-09 2017-05-10 塩野義製薬株式会社 複素環および炭素環誘導体
TWI637949B (zh) 2013-06-14 2018-10-11 塩野義製藥股份有限公司 胺基三衍生物及含有其等之醫藥組合物
WO2022162689A1 (en) * 2021-01-26 2022-08-04 Council Of Scientific And Industrial Research Triazine-based self-assembling system

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983116A (en) * 1973-04-05 1976-09-28 E. I. Du Pont De Nemours And Company Herbicidal triazines
US4035365A (en) * 1973-11-01 1977-07-12 Imperial Chemical Industries Limited Triazinediones
GB1543037A (en) * 1975-02-05 1979-03-28 Ici Ltd Selective herbicidal triazine-diones
GB1464248A (en) 1973-11-01 1977-02-09 Ici Ltd Substituted triazinediones their preparation and use as herbicides
US4082536A (en) * 1973-11-01 1978-04-04 Imperial Chemical Industries Limited Heterocyclic compounds and their use as pesticides
GB1504304A (en) * 1974-02-15 1978-03-15 Ici Ltd Process of combating fungal and bacterial infections of plants with triazine dione derivatives
GB1599518A (en) * 1977-02-21 1981-10-07 Ici Ltd 1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ZM4579A1 (en) 1981-05-21
PT69650A (en) 1979-06-01
AU4694979A (en) 1979-11-29
DE2962124D1 (en) 1982-03-25
DK213179A (da) 1979-11-27
IE49170B1 (en) 1985-08-21
AU529948B2 (en) 1983-06-30
ES480932A1 (es) 1980-02-01
GR68185B (de) 1981-11-09
US4254122A (en) 1981-03-03
NO791722L (no) 1979-11-27
NZ190402A (en) 1982-05-31
MW1379A1 (en) 1981-04-08
CS213377B2 (en) 1982-04-09
FI66180B (fi) 1984-05-31
CA1108138A (en) 1981-09-01
EP0005911B1 (de) 1982-02-17
JPS54154779A (en) 1979-12-06
ATE698T1 (de) 1982-03-15
IL57324A (en) 1983-10-31
PH14793A (en) 1981-12-09
ZA792247B (en) 1980-05-28
EP0005911A1 (de) 1979-12-12
FI791670A (fi) 1979-11-27
IE790889L (en) 1979-11-26
ZW9179A1 (en) 1981-01-21
IL57324A0 (en) 1979-09-30
DD143906A5 (de) 1980-09-17
HU180252B (en) 1983-02-28

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Owner name: IMPERIAL CHEMICAL INDUSTRIES LIMITED