CS208779B2 - Method of stabilization of the 4-methyl-5-/2'-chlorethyl/thiazole - Google Patents

Method of stabilization of the 4-methyl-5-/2'-chlorethyl/thiazole Download PDF

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Publication number
CS208779B2
CS208779B2 CS792752A CS275279A CS208779B2 CS 208779 B2 CS208779 B2 CS 208779B2 CS 792752 A CS792752 A CS 792752A CS 275279 A CS275279 A CS 275279A CS 208779 B2 CS208779 B2 CS 208779B2
Authority
CS
Czechoslovakia
Prior art keywords
cmt
carrier
mixture
base
decomposition
Prior art date
Application number
CS792752A
Other languages
Czech (cs)
English (en)
Inventor
Horst Felsch
Gerhard Hantich
Original Assignee
Pharmaceutical Licences Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaceutical Licences Co filed Critical Pharmaceutical Licences Co
Publication of CS208779B2 publication Critical patent/CS208779B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Lubricants (AREA)
CS792752A 1978-04-25 1979-04-20 Method of stabilization of the 4-methyl-5-/2'-chlorethyl/thiazole CS208779B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT296178A AT358530B (de) 1978-04-25 1978-04-25 Stabilisierungsverfahren

Publications (1)

Publication Number Publication Date
CS208779B2 true CS208779B2 (en) 1981-09-15

Family

ID=3543124

Family Applications (1)

Application Number Title Priority Date Filing Date
CS792752A CS208779B2 (en) 1978-04-25 1979-04-20 Method of stabilization of the 4-methyl-5-/2'-chlorethyl/thiazole

Country Status (23)

Country Link
US (1) US4247702A (fi)
EP (1) EP0005121B1 (fi)
JP (1) JPS54147914A (fi)
AT (1) AT358530B (fi)
AU (1) AU523518B2 (fi)
CA (1) CA1113941A (fi)
CS (1) CS208779B2 (fi)
DD (1) DD142962A5 (fi)
DE (2) DE2963835D1 (fi)
DK (1) DK155978C (fi)
ES (1) ES480590A1 (fi)
FI (1) FI66120C (fi)
GR (1) GR66987B (fi)
HU (1) HU179741B (fi)
IE (1) IE48778B1 (fi)
IL (1) IL57292A (fi)
NO (1) NO150317C (fi)
NZ (1) NZ190240A (fi)
PT (1) PT69532A (fi)
SU (1) SU959626A3 (fi)
UA (1) UA5545A1 (fi)
YU (1) YU42302B (fi)
ZA (1) ZA791661B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58159425A (ja) * 1982-03-18 1983-09-21 Fujisawa Pharmaceut Co Ltd ゲル基剤
SE9303281D0 (sv) * 1993-10-07 1993-10-07 Astra Ab New formulation
JP4332316B2 (ja) 1999-10-15 2009-09-16 スキャンポ・アーゲー 二環式化合物組成物およびその安定化方法
US9884024B2 (en) * 2005-12-27 2018-02-06 Hemant N Joshi Physically dispersed, molecularly dissolved and/or chemically bound drug(s) in an empty, hard capsule shell composition
JP2013032289A (ja) * 2009-10-28 2013-02-14 Daiichi Sankyo Co Ltd ワックス安定製剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2844512A (en) * 1954-11-05 1958-07-22 Upjohn Co Fumagillin enveloped in fatty or waxy substance and enclosed in ultraviolet opaque container
US3265629A (en) * 1958-12-22 1966-08-09 Ncr Co Coating by phase separation
US3146167A (en) * 1961-10-05 1964-08-25 Smith Kline French Lab Method of preparing sustained release pellets and products thereof
FR1416304A (fr) * 1961-10-10 1965-11-05 Smith Kline French Lab Perfectionnements apportés aux tablettes et comprimés renfermant une importante quantité d'ingrédient actif libéré pendant un laps de temps prolongé, et aux procédés pour leur préparation
FR1536904A (fr) * 1962-12-19 1968-09-02 Smith Kline French Lab Procédé de préparation de pilules pharmaceutiques à libération progressive de leur principe actif
SE319577B (fi) * 1966-03-08 1970-01-19 Astra Ab
JPS4971127A (fi) * 1972-11-18 1974-07-10
NL189235C (nl) * 1974-02-28 1993-02-16 Akzo Nv Werkwijze voor de bereiding van een oraal toe te dienen farmaceutisch preparaat met androgene werking.
NL7510104A (nl) * 1975-08-27 1977-03-01 Akzo Nv Werkwijze ter bereiding van een oraal werkzaam farmaceutisch preparaat.
US4202888A (en) * 1976-07-12 1980-05-13 Kali-Chemie Pharma Gmbh. Readily enterally absorbable pharmaceutical compositions of cardiac glycosides and preparation thereof
DE2631281A1 (de) * 1976-07-12 1978-01-19 Kali Chemie Pharma Gmbh Verfahren zur erhoehung der loeslichkeit von schwerloeslichen arzneistoffen zum zwecke deren applikation in gelatinekapseln

Also Published As

Publication number Publication date
EP0005121A2 (de) 1979-10-31
DK155978C (da) 1989-10-30
AT358530B (de) 1980-09-10
DD142962A5 (de) 1980-07-23
NZ190240A (en) 1980-10-24
JPS6337791B2 (fi) 1988-07-27
FI66120B (fi) 1984-05-31
AU4637379A (en) 1979-11-01
AU523518B2 (en) 1982-07-29
NO150317C (no) 1984-09-26
US4247702A (en) 1981-01-27
HU179741B (en) 1982-12-28
EP0005121A3 (en) 1979-11-28
IE48778B1 (en) 1985-05-15
ES480590A1 (es) 1980-08-16
ATA296178A (de) 1980-02-15
CA1113941A (en) 1981-12-08
DK155978B (da) 1989-06-12
SU959626A3 (ru) 1982-09-15
DE2916573A1 (de) 1979-10-31
YU42302B (en) 1988-08-31
JPS54147914A (en) 1979-11-19
YU91079A (en) 1984-10-31
DE2916573C2 (de) 1982-09-02
DE2963835D1 (en) 1982-11-18
ZA791661B (en) 1980-04-30
IL57292A (en) 1982-11-30
GR66987B (fi) 1981-05-15
EP0005121B1 (de) 1982-10-13
DK167879A (da) 1979-10-26
NO150317B (no) 1984-06-18
PT69532A (de) 1979-05-01
FI791324A (fi) 1979-10-26
IE790836L (en) 1979-10-25
NO791339L (no) 1979-10-26
UA5545A1 (uk) 1994-12-28
FI66120C (fi) 1984-09-10

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