CS207715B2 - Method of preparation of the 6-aminopenicillane acid - Google Patents

Method of preparation of the 6-aminopenicillane acid Download PDF

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Publication number
CS207715B2
CS207715B2 CS777745A CS774577A CS207715B2 CS 207715 B2 CS207715 B2 CS 207715B2 CS 777745 A CS777745 A CS 777745A CS 774577 A CS774577 A CS 774577A CS 207715 B2 CS207715 B2 CS 207715B2
Authority
CS
Czechoslovakia
Prior art keywords
penicillin
bed
catalyst
apa
depth
Prior art date
Application number
CS777745A
Other languages
Czech (cs)
English (en)
Inventor
James J Hamsher
Merrill Lozanov
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS207715B2 publication Critical patent/CS207715B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/42Compounds with a free primary amino radical attached in position 6
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/873Proteus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS777745A 1976-11-26 1977-11-23 Method of preparation of the 6-aminopenicillane acid CS207715B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/745,212 US4113566A (en) 1976-11-26 1976-11-26 Process for preparing 6-aminopenicillanic acid

Publications (1)

Publication Number Publication Date
CS207715B2 true CS207715B2 (en) 1981-08-31

Family

ID=24995717

Family Applications (1)

Application Number Title Priority Date Filing Date
CS777745A CS207715B2 (en) 1976-11-26 1977-11-23 Method of preparation of the 6-aminopenicillane acid

Country Status (29)

Country Link
US (1) US4113566A (sv)
JP (1) JPS5369888A (sv)
AR (1) AR218273A1 (sv)
AU (1) AU500707B1 (sv)
BE (1) BE861207A (sv)
BG (1) BG32859A3 (sv)
CA (1) CA1089383A (sv)
CH (1) CH625556A5 (sv)
CS (1) CS207715B2 (sv)
DD (1) DD133674A5 (sv)
DE (1) DE2752499C2 (sv)
DK (1) DK144277C (sv)
ES (1) ES464141A1 (sv)
FR (1) FR2372166A1 (sv)
GB (1) GB1537640A (sv)
HU (1) HU176598B (sv)
IE (1) IE45997B1 (sv)
IN (1) IN147632B (sv)
IT (1) IT1092206B (sv)
LU (1) LU78585A1 (sv)
MX (1) MX4233E (sv)
NL (1) NL171821C (sv)
PH (1) PH12580A (sv)
PL (1) PL109707B1 (sv)
RO (1) RO73018A (sv)
SE (1) SE434157B (sv)
SU (1) SU719504A3 (sv)
YU (1) YU267977A (sv)
ZA (1) ZA777018B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59110763U (ja) * 1983-01-18 1984-07-26 日産自動車株式会社 パ−キングブレ−キ力伝達装置
ES2135446T3 (es) * 1992-04-24 1999-11-01 Lilly Co Eli Procedimiento para la preparacion de cefalosporinas.
US6107067A (en) * 1998-07-06 2000-08-22 W.R. Grace & Co.-Conn. Porous, non-macroporous, inorganic oxide carrier body for immobilizing microorganisms for bioremediation
KR101822780B1 (ko) 2009-05-20 2018-01-26 질레코 인코포레이티드 바이오처리방법
ES2429912B1 (es) * 2012-05-14 2014-11-26 Universidad Autónoma de Madrid Polipéptido termoestable con actividad penicilina acilasa, variantes del mismo y sus aplicaciones
CN105254520B (zh) * 2015-10-12 2017-07-07 国药集团威奇达药业有限公司 酶法合成阿莫西林结晶母液中d‑对羟基苯甘氨酸的回收方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3239427A (en) * 1959-10-12 1966-03-08 Pfizer & Co C Production of 6-aminopenicillanic acid
US3694314A (en) * 1970-11-09 1972-09-26 Standard Brands Inc Process for isomerizing glucose to fructose
US3817832A (en) * 1970-11-09 1974-06-18 Standard Brands Inc Process for isomerizing glucose to fructose
IL39158A (en) 1971-04-28 1977-08-31 Snam Progetti Enzymatic scission and synthesis of penicillins and cephalosporins
BE791748A (fr) * 1971-11-23 1973-05-22 Bayer Ag Procede de production d'acide 6-aminopenicillanique par ruptureenzymatique de penicillines
DE2215539C2 (de) * 1972-03-30 1984-08-02 Bayer Ag, 5090 Leverkusen Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate
GB1400468A (en) * 1972-07-22 1975-07-16 Beecham Group Ltd Enzyme preparation and use thereof
JPS5317674B2 (sv) * 1973-05-30 1978-06-09
CH597237A5 (sv) * 1974-01-31 1978-03-31 Biochemie Gmbh
US3905868A (en) * 1974-12-04 1975-09-16 Pfizer Enzymatic deacylation of benzyl- and phenoxymethylpenicillin tetrazoles

Also Published As

Publication number Publication date
CA1089383A (en) 1980-11-11
JPS5369888A (en) 1978-06-21
BG32859A3 (en) 1982-10-15
SE434157B (sv) 1984-07-09
YU267977A (en) 1982-06-30
AR218273A1 (es) 1980-05-30
LU78585A1 (fr) 1979-06-13
DD133674A5 (de) 1979-01-17
DK524977A (da) 1978-05-27
IT1092206B (it) 1985-07-06
IE45997B1 (en) 1983-01-26
NL171821C (nl) 1983-05-16
PH12580A (en) 1979-06-20
IE45997L (en) 1978-05-26
HU176598B (en) 1981-03-28
NL171821B (nl) 1982-12-16
DE2752499A1 (de) 1978-06-01
PL109707B1 (en) 1980-06-30
US4113566A (en) 1978-09-12
MX4233E (es) 1982-02-19
DK144277C (da) 1982-07-05
IN147632B (sv) 1980-05-03
AU500707B1 (en) 1979-05-31
SE7712006L (sv) 1978-05-27
FR2372166B1 (sv) 1982-12-17
CH625556A5 (sv) 1981-09-30
JPS5650839B2 (sv) 1981-12-01
BE861207A (fr) 1978-05-25
RO73018A (ro) 1981-11-04
GB1537640A (en) 1979-01-04
DE2752499C2 (de) 1986-05-07
ZA777018B (en) 1978-09-27
PL202402A1 (pl) 1978-08-28
NL7712999A (nl) 1978-05-30
ES464141A1 (es) 1978-09-01
FR2372166A1 (fr) 1978-06-23
SU719504A3 (ru) 1980-02-29
DK144277B (da) 1982-02-01

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