CS200483B2 - Process for preparing 6-methyl-8-/2-methylsulphinylethyl/ergoline - Google Patents

Process for preparing 6-methyl-8-/2-methylsulphinylethyl/ergoline Download PDF

Info

Publication number
CS200483B2
CS200483B2 CS757859A CS785975A CS200483B2 CS 200483 B2 CS200483 B2 CS 200483B2 CS 757859 A CS757859 A CS 757859A CS 785975 A CS785975 A CS 785975A CS 200483 B2 CS200483 B2 CS 200483B2
Authority
CS
Czechoslovakia
Prior art keywords
compound
methyl
acid
ergoline
reacting
Prior art date
Application number
CS757859A
Other languages
Czech (cs)
English (en)
Inventor
Edmund C Kornfeld
Nicholas J Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS793204A priority Critical patent/CS200484B2/cs
Publication of CS200483B2 publication Critical patent/CS200483B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS757859A 1974-12-06 1975-11-20 Process for preparing 6-methyl-8-/2-methylsulphinylethyl/ergoline CS200483B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS793204A CS200484B2 (cs) 1974-12-06 1979-05-10 Způsob výroby 6-methyl-8-nitromethylergolinu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/530,318 US3985752A (en) 1974-12-06 1974-12-06 6-Methyl-8-(substituted) methylergolines

Publications (1)

Publication Number Publication Date
CS200483B2 true CS200483B2 (en) 1980-09-15

Family

ID=24113213

Family Applications (2)

Application Number Title Priority Date Filing Date
CS757859A CS200483B2 (en) 1974-12-06 1975-11-20 Process for preparing 6-methyl-8-/2-methylsulphinylethyl/ergoline
CS757860A CS199609B2 (en) 1974-12-06 1975-11-20 Method of producing 6-methyl-8-isocyanmethyl ergoline

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS757860A CS199609B2 (en) 1974-12-06 1975-11-20 Method of producing 6-methyl-8-isocyanmethyl ergoline

Country Status (29)

Country Link
US (1) US3985752A (ko)
JP (2) JPS5946235B2 (ko)
AR (2) AR208104A1 (ko)
AT (2) AT347050B (ko)
AU (1) AU498226B2 (ko)
BE (1) BE836308A (ko)
BG (3) BG33287A3 (ko)
CA (2) CA1062252A (ko)
CH (2) CH617197A5 (ko)
CS (2) CS200483B2 (ko)
DD (2) DD123749A5 (ko)
DE (1) DE2554000A1 (ko)
DK (2) DK547675A (ko)
ES (3) ES443276A1 (ko)
FR (1) FR2293203A1 (ko)
GB (1) GB1526835A (ko)
GR (2) GR60026B (ko)
HU (3) HU173724B (ko)
IE (1) IE42372B1 (ko)
IL (1) IL48573A (ko)
MX (1) MX3113E (ko)
NL (1) NL7514058A (ko)
PH (1) PH12630A (ko)
PL (3) PL102195B1 (ko)
RO (2) RO64281A (ko)
SE (2) SE421422B (ko)
SU (3) SU685155A3 (ko)
YU (2) YU304875A (ko)
ZA (1) ZA757624B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
HU180467B (en) * 1979-07-12 1983-03-28 Gyogyszerkutato Intezet Process for producing new ergol-8-ene- and ergoline-sceleted compounds
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
JPH0541005Y2 (ko) * 1987-07-14 1993-10-18
JPH02174820A (ja) * 1988-12-27 1990-07-06 Sekisui Chem Co Ltd トイレット
WO2000054776A1 (en) * 1999-03-17 2000-09-21 Eugen Eigenmann Use of prolactin inhibitors for the treatment of fertility problems in animal species
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695752C3 (de) * 1966-07-29 1974-06-06 Societa Farmaceutici Italia, Mailand (Italien) 1 ,ö-Dimethyl-ebeta-N-carbobenzoxyaminomethyl-2,3-dihydro-1 Oalpha-ergolin und ein Verfahren zu seiner Herstellung
BE712054A (ko) * 1967-03-16 1968-07-15

Also Published As

Publication number Publication date
CH617197A5 (ko) 1980-05-14
FR2293203A1 (fr) 1976-07-02
JPS6017795B2 (ja) 1985-05-07
DD123749A5 (ko) 1977-01-12
YU304875A (en) 1982-02-28
PL102198B1 (pl) 1979-03-31
JPS59210085A (ja) 1984-11-28
JPS5182300A (ko) 1976-07-19
SE7513641L (sv) 1976-06-08
DK142321C (ko) 1981-03-09
AR207664A1 (es) 1976-10-22
IL48573A (en) 1979-03-12
AT348141B (de) 1979-01-25
NL7514058A (nl) 1976-06-09
CS199609B2 (en) 1980-07-31
CA1062252A (en) 1979-09-11
DD123748A5 (ko) 1977-01-12
SU694075A3 (ru) 1979-10-25
CH619465A5 (ko) 1980-09-30
HU175228B (hu) 1980-06-28
SU685155A3 (ru) 1979-09-05
AU8718275A (en) 1977-06-09
JPS5946235B2 (ja) 1984-11-10
BG33287A3 (en) 1983-01-14
US3985752A (en) 1976-10-12
PH12630A (en) 1979-07-05
IE42372L (en) 1976-06-06
IE42372B1 (en) 1980-07-30
HU173724B (hu) 1979-07-28
MX3113E (es) 1980-04-18
GR60026B (en) 1978-03-31
IL48573A0 (en) 1976-01-30
GR60025B (en) 1978-03-31
YU304775A (en) 1982-02-28
SE421423B (sv) 1981-12-21
BG33435A3 (en) 1983-02-15
ES443276A1 (es) 1977-08-16
DE2554000A1 (de) 1976-06-16
RO64281A (fr) 1979-07-15
BE836308A (fr) 1976-06-08
SE421422B (sv) 1981-12-21
BG33288A3 (en) 1983-01-14
AU498226B2 (en) 1979-02-22
ES443275A1 (es) 1977-09-16
HU173847B (hu) 1979-09-28
CA1062253A (en) 1979-09-11
SU724085A3 (ru) 1980-03-25
DK547675A (da) 1976-06-07
PL106884B1 (pl) 1980-01-31
ATA927975A (de) 1978-04-15
DK142321B (da) 1980-10-13
ATA927875A (de) 1978-06-15
RO65456A (ro) 1980-01-15
PL102195B1 (pl) 1979-03-31
GB1526835A (en) 1978-10-04
ZA757624B (en) 1977-07-27
ES457709A1 (es) 1978-03-01
AR208104A1 (es) 1976-11-30
SE7513640L (sv) 1976-06-08
DK547575A (ko) 1976-06-07
USB530318I5 (ko) 1976-01-13
AT347050B (de) 1978-12-11
FR2293203B1 (ko) 1978-07-28

Similar Documents

Publication Publication Date Title
CS199591B2 (en) Process for preparing 8-thimethylergolines
CS200483B2 (en) Process for preparing 6-methyl-8-/2-methylsulphinylethyl/ergoline
CS207666B2 (en) Method of making the 2-bromergosin and the additive salts thereof with the acid
US3968111A (en) 8,8-Disubstituted-6-methylergolines and related compounds
US3933827A (en) 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
IL42730A (en) D-6-methyl-2,8-disubstituted ergolines,their preparation and pharmaceutical compositions containing them
US4299836A (en) Novel ergol-8-ene and ergolin compounds and process for preparing same
US3583992A (en) 1-methyl-d-lysergic acid-dihydroxy-alkyl-amides
JPH0344392A (ja) ４Ｈ‐インドロ〔１，２‐ｄ〕〔１，２，４〕トリアゾロ〔４，３‐ａ〕〔１，４〕ベンゾジアゼピンおよびその製造法
US4440772A (en) Acid addition salts of dextrorotatory ergot alkaloids, a process for the preparation thereof as well as their use as medicines
FI71736B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara erolinderivat och deras syraadditionssalter
KR800000413B1 (ko) 6-메틸-8-(치환)메틸 에르골린류의 제조방법
HU192728B (en) Process for producing 4-oxo-pyrido/2,3-d/pyrimidine derivatives and pharmaceutical compositions containing them
KR800000414B1 (ko) 6-메티-8-(치환)메틸에르골린류의 제조방법
HU207079B (en) Process for producing pyrido (2,3-g)quinoline derivatives having dopamin agonist activity and pharmaceutical compositions comprising same
JPS5910358B2 (ja) 新規エルゴリン誘導体
CS200484B2 (cs) Způsob výroby 6-methyl-8-nitromethylergolinu
KR800000558B1 (ko) 6-메틸-8-(치환) 메틸에르골린류의 제조방법
USRE30218E (en) 8,8-Disubstituted-6-methylergolines and related compounds
USRE30219E (en) Method of preparing 8,8-disubstituted-6-methylergolines and related compounds
KR790001074B1 (ko) 8,8-이치환-6-메틸에르골린류의 제조방법
EP0378706A1 (en) 5-substituted uridine derivatives and intermediates for their preparation
KR840001473B1 (ko) 에르골린 유도체의 제조방법
KR810002024B1 (ko) 6-n-프로필-8-메톡시메틸 또는 메틸 메르캅토 메틸 에르골린의 제조방법
BG61058B2 (bg) Диметиламиноалкил-3-(ерголин-8'бета-карбонил)-карбамиди