CS196406B2 - Process for preparing derivatives of 3-aminoethyl-2-phenylcyclooctane - Google Patents

Process for preparing derivatives of 3-aminoethyl-2-phenylcyclooctane Download PDF

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Publication number
CS196406B2
CS196406B2 CS763025A CS302576A CS196406B2 CS 196406 B2 CS196406 B2 CS 196406B2 CS 763025 A CS763025 A CS 763025A CS 302576 A CS302576 A CS 302576A CS 196406 B2 CS196406 B2 CS 196406B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
cis
hydrogen
alkyl
reaction
Prior art date
Application number
CS763025A
Other languages
Czech (cs)
English (en)
Inventor
David Ch Horwell
Graham H Timms
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to CS776149A priority Critical patent/CS196407B2/cs
Publication of CS196406B2 publication Critical patent/CS196406B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CS763025A 1975-05-08 1976-05-06 Process for preparing derivatives of 3-aminoethyl-2-phenylcyclooctane CS196406B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS776149A CS196407B2 (cs) 1975-05-08 1977-09-22 Způsob výroby ž-tenylbicyklookíanových a oktenových derivátů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19348/75A GB1549174A (en) 1975-05-08 1975-05-08 Amine derivatives

Publications (1)

Publication Number Publication Date
CS196406B2 true CS196406B2 (en) 1980-03-31

Family

ID=10127854

Family Applications (1)

Application Number Title Priority Date Filing Date
CS763025A CS196406B2 (en) 1975-05-08 1976-05-06 Process for preparing derivatives of 3-aminoethyl-2-phenylcyclooctane

Country Status (38)

Country Link
US (1) US4705807A (fr)
JP (1) JPS6039069B2 (fr)
AR (2) AR211926A1 (fr)
AT (1) AT346825B (fr)
AU (1) AU503324B2 (fr)
BE (1) BE841634A (fr)
BG (1) BG28043A3 (fr)
CA (1) CA1077500A (fr)
CH (1) CH609672A5 (fr)
CS (1) CS196406B2 (fr)
CY (1) CY1151A (fr)
DD (1) DD123988A5 (fr)
DE (1) DE2619617A1 (fr)
DK (1) DK147577C (fr)
ES (1) ES447715A1 (fr)
FI (1) FI61868C (fr)
FR (1) FR2310126A1 (fr)
GB (1) GB1549174A (fr)
GR (1) GR59904B (fr)
HK (1) HK25682A (fr)
HU (1) HU176277B (fr)
IE (1) IE43132B1 (fr)
IL (1) IL49438A (fr)
LU (1) LU74896A1 (fr)
MX (1) MX3454E (fr)
MY (1) MY8300054A (fr)
NL (1) NL7604882A (fr)
NO (1) NO142218C (fr)
NZ (1) NZ180657A (fr)
OA (1) OA05206A (fr)
PH (1) PH13678A (fr)
PL (2) PL103979B1 (fr)
PT (1) PT65074B (fr)
RO (1) RO70770A (fr)
SE (2) SE426585B (fr)
SU (2) SU602112A3 (fr)
YU (1) YU113576A (fr)
ZA (1) ZA762378B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215074A (en) * 1978-07-15 1980-07-29 Lilly Industries Limited Process for preparing cis-bicyclooctylamines
CA1130318A (fr) * 1978-10-11 1982-08-24 Peter M. Muller Derives du cyclohexadiene
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
DE4019782A1 (de) * 1990-06-21 1992-01-02 Basf Ag 9-amino-2-phenylbicyclo (3.3.1.) und 9-amino-2-phenylbicyclo (3.3.1.) non-2-ene und diese enthaltende therapeutische mittel
GB9908021D0 (en) * 1999-04-08 1999-06-02 Lilly Co Eli Pharmaceutical compounds
GB2367554A (en) * 2000-10-04 2002-04-10 Lilly Co Eli Pharmacologically active amines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB873018A (en) * 1958-09-22 1961-07-19 Smith Kline French Lab Substituted phenylcyclopropylamines
US3133901A (en) * 1960-08-11 1964-05-19 Mcneilab Inc Aminonorbornanes and their preparation
GB992734A (en) * 1961-11-10 1965-05-19 Smith Kline French Lab Improvements in or relating to novel trans-3-phenylcyclobutylamines
US3308160A (en) * 1963-06-26 1967-03-07 Du Pont 4-phenylbicyclo[2.2.2]octane-1-amines and salts thereof
US3413348A (en) * 1965-06-28 1968-11-26 Du Pont 4-phenylbicyclo[2.2.2.]oct-2-ene-1-amine and salts thereof
US3362878A (en) * 1966-08-01 1968-01-09 Du Pont Pharmaceutical compositions and methods utilizing substituted bicyclo[2.2.2]-octanes
US3742055A (en) * 1969-07-31 1973-06-26 Colgate Palmolive Co 3-amino-bicyclo{8 2.2.2{9 octan-2-ols
US3980785A (en) * 1972-11-04 1976-09-14 Lilly Industries, Ltd. Secondary and tertiary-2-phenylbicyclo[2,2,2]oct-3-yl alkylamines and composition thereof
GB1444717A (en) * 1972-11-04 1976-08-04 Lilly Industries Ltd Bicycloalkyl derivatives

Also Published As

Publication number Publication date
OA05206A (fr) 1981-02-28
PT65074A (en) 1976-06-01
SU602112A3 (ru) 1978-04-05
HU176277B (en) 1981-01-28
DE2619617A1 (de) 1976-11-18
CY1151A (en) 1982-09-10
SU680642A3 (ru) 1979-08-15
ZA762378B (en) 1977-04-27
JPS6039069B2 (ja) 1985-09-04
SE426585B (sv) 1983-01-31
MX3454E (es) 1980-12-03
CA1077500A (fr) 1980-05-13
FR2310126A1 (fr) 1976-12-03
IL49438A0 (en) 1976-06-30
PL106888B1 (pl) 1980-01-31
LU74896A1 (fr) 1977-12-13
DD123988A5 (fr) 1977-01-26
PL103979B1 (pl) 1979-07-31
BE841634A (fr) 1976-11-08
ATA328376A (de) 1978-04-15
HK25682A (en) 1982-06-18
DK147577B (da) 1984-10-08
DK147577C (da) 1985-03-18
SE431641B (sv) 1984-02-20
SE7605146L (sv) 1976-11-09
YU113576A (en) 1983-01-21
NZ180657A (en) 1978-06-20
GB1549174A (en) 1979-08-01
CH609672A5 (fr) 1979-03-15
PH13678A (en) 1980-08-29
PT65074B (en) 1978-05-08
SE8000363L (sv) 1980-01-16
AR218619A1 (es) 1980-06-30
FR2310126B1 (fr) 1980-07-04
NO142218C (no) 1980-07-16
MY8300054A (en) 1983-12-31
FI61868C (fi) 1982-10-11
US4705807A (en) 1987-11-10
AU503324B2 (en) 1979-08-30
AU1375576A (en) 1977-11-10
FI761292A (fr) 1976-11-09
AT346825B (de) 1978-11-27
IL49438A (en) 1980-01-31
IE43132B1 (en) 1980-12-31
NO142218B (no) 1980-04-08
NL7604882A (nl) 1976-11-10
BG28043A3 (en) 1980-02-25
GR59904B (en) 1978-03-16
NO761550L (fr) 1976-11-09
JPS51138661A (en) 1976-11-30
FI61868B (fi) 1982-06-30
DE2619617C2 (fr) 1987-10-01
DK202876A (da) 1976-11-09
RO70770A (fr) 1981-11-04
ES447715A1 (es) 1977-06-01
AR211926A1 (es) 1978-04-14

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