CS181591A3 - Injectable galenical formulation with retarded activity - Google Patents
Injectable galenical formulation with retarded activityInfo
- Publication number
- CS181591A3 CS181591A3 CS911815A CS181591A CS181591A3 CS 181591 A3 CS181591 A3 CS 181591A3 CS 911815 A CS911815 A CS 911815A CS 181591 A CS181591 A CS 181591A CS 181591 A3 CS181591 A3 CS 181591A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- carrier
- drug
- microspheres
- injectable
- recipient
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- 239000004005 microsphere Substances 0.000 abstract 3
- 235000012000 cholesterol Nutrition 0.000 abstract 2
- LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000011261 inert gas Substances 0.000 abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 abstract 2
- DIWRORZWFLOCLC-HNNXBMFYSA-N (3s)-7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one Chemical compound N([C@H](C(NC1=CC=C(Cl)C=C11)=O)O)=C1C1=CC=CC=C1Cl DIWRORZWFLOCLC-HNNXBMFYSA-N 0.000 abstract 1
- FQRHOOHLUYHMGG-BTJKTKAUSA-N 3-(2-acetylphenothiazin-10-yl)propyl-dimethylazanium;(z)-4-hydroxy-4-oxobut-2-enoate Chemical compound OC(=O)\C=C/C(O)=O.C1=C(C(C)=O)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 FQRHOOHLUYHMGG-BTJKTKAUSA-N 0.000 abstract 1
- 108010007979 Glycocholic Acid Proteins 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- RFDAIACWWDREDC-UHFFFAOYSA-N Na salt-Glycocholic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCC(O)=O)C)C1(C)C(O)C2 RFDAIACWWDREDC-UHFFFAOYSA-N 0.000 abstract 1
- HWHLPVGTWGOCJO-UHFFFAOYSA-N Trihexyphenidyl Chemical group C1CCCCC1C(C=1C=CC=CC=1)(O)CCN1CCCCC1 HWHLPVGTWGOCJO-UHFFFAOYSA-N 0.000 abstract 1
- 229960001946 acepromazine maleate Drugs 0.000 abstract 1
- QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 abstract 1
- YSXKPIUOCJLQIE-UHFFFAOYSA-N biperiden Chemical compound C1C(C=C2)CC2C1C(C=1C=CC=CC=1)(O)CCN1CCCCC1 YSXKPIUOCJLQIE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003003 biperiden Drugs 0.000 abstract 1
- DGBIGWXXNGSACT-UHFFFAOYSA-N clonazepam Chemical compound C12=CC([N+](=O)[O-])=CC=C2NC(=O)CN=C1C1=CC=CC=C1Cl DGBIGWXXNGSACT-UHFFFAOYSA-N 0.000 abstract 1
- 229960003120 clonazepam Drugs 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- QYIXCDOBOSTCEI-NWKZBHTNSA-N coprostanol Chemical compound C([C@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-NWKZBHTNSA-N 0.000 abstract 1
- AAOVKJBEBIDNHE-UHFFFAOYSA-N diazepam Chemical compound N=1CC(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 AAOVKJBEBIDNHE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003529 diazepam Drugs 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001253 domperidone Drugs 0.000 abstract 1
- FGXWKSZFVQUSTL-UHFFFAOYSA-N domperidone Chemical compound C12=CC=CC=C2NC(=O)N1CCCN(CC1)CCC1N1C2=CC=C(Cl)C=C2NC1=O FGXWKSZFVQUSTL-UHFFFAOYSA-N 0.000 abstract 1
- RFDAIACWWDREDC-FRVQLJSFSA-N glycocholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 RFDAIACWWDREDC-FRVQLJSFSA-N 0.000 abstract 1
- 229940099347 glycocholic acid Drugs 0.000 abstract 1
- 229960003878 haloperidol Drugs 0.000 abstract 1
- 229960004391 lorazepam Drugs 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 229960004503 metoclopramide Drugs 0.000 abstract 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229960001032 trihexyphenidyl Drugs 0.000 abstract 1
- 229960002726 vincamine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Steroid Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9007417A FR2663224B1 (fr) | 1990-06-14 | 1990-06-14 | Forme galenique parenterale. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS181591A3 true CS181591A3 (en) | 1992-06-17 |
| CZ286199B6 CZ286199B6 (cs) | 2000-02-16 |
Family
ID=9397599
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5643604A (cs) |
| EP (1) | EP0487674B1 (cs) |
| JP (1) | JP2690398B2 (cs) |
| KR (1) | KR0157438B1 (cs) |
| CN (1) | CN1058608C (cs) |
| AT (1) | ATE117546T1 (cs) |
| AU (1) | AU643540B2 (cs) |
| BG (1) | BG61178B1 (cs) |
| BR (1) | BR9105782A (cs) |
| CA (1) | CA2064861C (cs) |
| CZ (1) | CZ286199B6 (cs) |
| DE (1) | DE69107026T2 (cs) |
| DK (1) | DK0487674T3 (cs) |
| ES (1) | ES2068592T3 (cs) |
| FI (1) | FI107697B (cs) |
| FR (1) | FR2663224B1 (cs) |
| GR (1) | GR3015809T3 (cs) |
| HU (1) | HU219461B (cs) |
| IE (1) | IE69172B1 (cs) |
| IL (1) | IL98458A (cs) |
| NO (2) | NO302927B1 (cs) |
| NZ (1) | NZ238543A (cs) |
| PH (1) | PH30243A (cs) |
| PL (1) | PL167177B1 (cs) |
| PT (1) | PT97976B (cs) |
| RO (1) | RO110198B1 (cs) |
| RU (1) | RU2095055C1 (cs) |
| SK (1) | SK279867B6 (cs) |
| TN (1) | TNSN91047A1 (cs) |
| TW (1) | TW205511B (cs) |
| UY (1) | UY23239A1 (cs) |
| WO (1) | WO1991019485A1 (cs) |
| ZA (1) | ZA914549B (cs) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| IL109460A (en) | 1993-05-10 | 1998-03-10 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| US6416778B1 (en) | 1997-01-24 | 2002-07-09 | Femmepharma | Pharmaceutical preparations and methods for their regional administration |
| US5993856A (en) * | 1997-01-24 | 1999-11-30 | Femmepharma | Pharmaceutical preparations and methods for their administration |
| US6287693B1 (en) * | 1998-02-25 | 2001-09-11 | John Claude Savoir | Stable shaped particles of crystalline organic compounds |
| GB9819272D0 (en) * | 1998-09-03 | 1998-10-28 | Andaris Ltd | Microparticles |
| JP2002540136A (ja) | 1999-03-26 | 2002-11-26 | ポウズン インコーポレイテッド | 高い効力を有するジヒドロエルゴタミン組成物 |
| DE19940795A1 (de) * | 1999-08-27 | 2001-03-01 | Lohmann Therapie Syst Lts | Schnellzerfallende Pellets auf der Basis von Chitosan |
| DE50202200D1 (de) * | 2001-09-27 | 2005-03-17 | Cognis Deutschland Gmbh | Kugelförmige Sterinzubereitungen, deren Herstellung und Verwendung |
| AU2002336653A1 (en) * | 2001-10-24 | 2003-05-06 | Luciano Mastronardi | Management of postoperative pain |
| AU2002366800B2 (en) * | 2001-12-20 | 2006-08-03 | Femmepharma Holding Company, Inc. | Vaginal delivery of drugs |
| RU2205634C1 (ru) * | 2002-06-18 | 2003-06-10 | Нестерук Владимир Викторович | Лекарственное средство, обладающее противорвотным действием |
| EP1578437A4 (en) * | 2002-12-27 | 2006-08-09 | Diobex Inc | COMPOSITIONS AND METHODS FOR PREVENTING AND REDUCING INSULIN-INDUCED HYPOGLYCEMIA |
| US7655618B2 (en) * | 2002-12-27 | 2010-02-02 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
| JP2006515026A (ja) * | 2003-01-02 | 2006-05-18 | フェムファーマ ホールディング カンパニー， インコーポレイテッド | 乳房の疾患および障害の処置のための薬学的調製物 |
| US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
| SI1844765T1 (sl) * | 2003-06-13 | 2015-05-29 | Skendi Finance, Ltd. | Formulacija estradiola in progesterona s počasnim sproščanjem |
| US7413690B1 (en) | 2003-10-29 | 2008-08-19 | The University Of Mississippi | Process and apparatus for producing spherical pellets using molten solid matrices |
| US7491263B2 (en) | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
| JP4940152B2 (ja) | 2005-01-05 | 2012-05-30 | イーライ リリー アンド カンパニー | パモ酸オランザピン二水和物 |
| WO2007072491A2 (en) * | 2005-12-21 | 2007-06-28 | Baskaran Chandrasekar | Sustained release pharmaceutical formulation and treatment of ischemic heart disease by administering the same |
| BRPI0719280A2 (pt) | 2006-11-27 | 2014-03-11 | Lundbeck & Co As H | Composto, composição farmacêutica, métodos para modular a atividade de um receptor de p2x7 in vitro e em um paciente, para tratar uma condição responsiva à modulação do receptor de p2x7 em um paciente, para inibir a morte de células do gânglio retinal em um paciente, para determinar a presença ou ausência de receptor de p2x7 em uma amostra, preparação farmacêutica acondicionada, método para tratar ou prevenir cirrose em um paciente, e, uso de um composto. |
| US20080153789A1 (en) * | 2006-12-26 | 2008-06-26 | Femmepharma Holding Company, Inc. | Topical administration of danazol |
| BRPI0822165A2 (pt) | 2008-04-14 | 2015-06-16 | Posi Visionary Solutions Llp | Método para manter concentrações plasmáticas sustentadas de progesterona em seres humanos, composição farmacêutica, uso de uma composição farmecêutica e suspensão aquosa injetável. |
| RU2395139C1 (ru) * | 2009-04-10 | 2010-07-20 | Российская Федерация, от имени которой выступает Государственная корпорация по атомной энергии "Росатом" | Способ изготовления волновода переменного сечения |
| US20110003000A1 (en) * | 2009-07-06 | 2011-01-06 | Femmepharma Holding Company, Inc. | Transvaginal Delivery of Drugs |
| UY33103A (es) | 2009-12-15 | 2011-07-29 | Techsphere S A De C V | Formulacion farmaceutica parenteral en suspension, de liberacion sostenida, en dosis baja y ultra baja, en terapia hormonal en el sindrome climaterico |
| EP2523666B8 (en) * | 2010-01-14 | 2016-04-06 | Asarina Pharma AB | A pharmaceutical composition comprising 3-beta-hydroxy-5-alpha-pregnan-20-one with improved storage and solubility properties |
| RU2576236C1 (ru) * | 2014-08-22 | 2016-02-27 | Александр Александрович Кролевец | Способ получения нанокапсул антибиотиков в агар-агаре |
| RU2577689C1 (ru) * | 2014-08-26 | 2016-03-20 | Александр Александрович Кролевец | Способ получения нанокапсул антибиотиков в агар-агаре |
| RU2578408C1 (ru) * | 2014-09-10 | 2016-03-27 | Александр Александрович Кролевец | Способ получения нанокапсул алкалоидов |
| ITUB20153652A1 (it) * | 2015-09-16 | 2017-03-16 | Fatro Spa | Microsfere contenenti lattoni macrociclici antielminitici |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE744162A (fr) * | 1969-01-16 | 1970-06-15 | Fuji Photo Film Co Ltd | Procede d'encapsulage |
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3937668A (en) * | 1970-07-15 | 1976-02-10 | Ilse Zolle | Method for incorporating substances into protein microspheres |
| DK123067B (da) * | 1970-09-25 | 1972-05-15 | Niro Atomizer As | Fremgangsmåde til behandling af et pulverformigt, fedtholdigt mælkeprodukt. |
| JPS5017525A (cs) * | 1973-06-14 | 1975-02-24 | ||
| US3982537A (en) * | 1974-12-30 | 1976-09-28 | Louis Bucalo | Dynamic implants and method for implanting the same |
| CA1077842A (en) * | 1975-10-09 | 1980-05-20 | Minnesota Mining And Manufacturing Company | Albumin medicament carrier system |
| IT1202370B (it) * | 1976-07-12 | 1989-02-09 | Hoffmann La Roche | Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti |
| US4357259A (en) * | 1977-08-01 | 1982-11-02 | Northwestern University | Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres |
| US4244949A (en) * | 1978-04-06 | 1981-01-13 | The Population Council, Inc. | Manufacture of long term contraceptive implant |
| US4331654A (en) * | 1980-06-13 | 1982-05-25 | Eli Lilly And Company | Magnetically-localizable, biodegradable lipid microspheres |
| US4384975A (en) * | 1980-06-13 | 1983-05-24 | Sandoz, Inc. | Process for preparation of microspheres |
| US4349530A (en) * | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
| FR2524312B1 (fr) * | 1982-04-01 | 1985-10-04 | Tech Cuir Centre | Nouvelles formes de micro-encapsulation de substances medicamenteuses par des couches homogenes de collagene natif |
| US4492720A (en) * | 1983-11-15 | 1985-01-08 | Benjamin Mosier | Method of preparing microspheres for intravascular delivery |
| US4963367A (en) * | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
| JPS61174940A (ja) * | 1985-01-29 | 1986-08-06 | Oogawara Kakoki Kk | ワックス類コーテイング単核状マイクロカプセルおよびその製造方法 |
| US4675173A (en) * | 1985-05-08 | 1987-06-23 | Molecular Biosystems, Inc. | Method of magnetic resonance imaging of the liver and spleen |
| IL79407A (en) * | 1985-08-01 | 1991-03-10 | Theragenics Corp | System and method for delivering insoluble material into a living body |
| US4837381A (en) * | 1986-08-11 | 1989-06-06 | American Cyanamid Company | Compositions for parenteral administration and their use |
| ATE74009T1 (de) * | 1986-08-11 | 1992-04-15 | American Cyanamid Co | Zusammensetzungen zur parenteralen verabreichung und deren verwendung. |
| CA1319886C (en) * | 1987-02-03 | 1993-07-06 | Alberto Ferro | Mixed micelle solutions |
| EP0357644B1 (en) * | 1987-04-06 | 1994-08-17 | Aberlyn Capital Management Limited Partnership | Flash flow fused medicinal implants |
| US4748024A (en) * | 1987-04-06 | 1988-05-31 | Endocon, Inc. | Flash flow fused medicinal implants |
| US4892734A (en) * | 1987-04-06 | 1990-01-09 | Endocon, Inc. | Dispensing paste for forming medicinal pellets |
| AU4369589A (en) * | 1988-10-27 | 1990-05-03 | Abbott Laboratories | Controlled-release delivery device, method for producing device, and method of using device |
| US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| US5085864A (en) * | 1989-10-30 | 1992-02-04 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
| FR2663223B1 (fr) * | 1990-06-14 | 1994-12-02 | Af Aplicaciones Far Lab | Forme galenique parenterale. |
-
1990
- 1990-06-14 FR FR9007417A patent/FR2663224B1/fr not_active Expired - Fee Related
-
1991
- 1991-06-11 IL IL9845891A patent/IL98458A/en not_active IP Right Cessation
- 1991-06-12 RU SU915011663A patent/RU2095055C1/ru active
- 1991-06-12 DE DE69107026T patent/DE69107026T2/de not_active Expired - Fee Related
- 1991-06-12 EP EP91910873A patent/EP0487674B1/fr not_active Expired - Lifetime
- 1991-06-12 JP JP3510713A patent/JP2690398B2/ja not_active Expired - Lifetime
- 1991-06-12 RO RO92-200136A patent/RO110198B1/ro unknown
- 1991-06-12 AT AT91910873T patent/ATE117546T1/de not_active IP Right Cessation
- 1991-06-12 ES ES91910873T patent/ES2068592T3/es not_active Expired - Lifetime
- 1991-06-12 AU AU80667/91A patent/AU643540B2/en not_active Ceased
- 1991-06-12 HU HU9200775A patent/HU219461B/hu not_active IP Right Cessation
- 1991-06-12 BR BR919105782A patent/BR9105782A/pt not_active Application Discontinuation
- 1991-06-12 CA CA002064861A patent/CA2064861C/fr not_active Expired - Fee Related
- 1991-06-12 KR KR1019920700315A patent/KR0157438B1/ko not_active Expired - Fee Related
- 1991-06-12 WO PCT/EP1991/001097 patent/WO1991019485A1/fr not_active Ceased
- 1991-06-12 DK DK91910873.8T patent/DK0487674T3/da active
- 1991-06-13 IE IE201891A patent/IE69172B1/en not_active IP Right Cessation
- 1991-06-13 UY UY23239A patent/UY23239A1/es not_active IP Right Cessation
- 1991-06-13 CZ CS19911815A patent/CZ286199B6/cs not_active IP Right Cessation
- 1991-06-13 SK SK1815-91A patent/SK279867B6/sk unknown
- 1991-06-14 PT PT97976A patent/PT97976B/pt not_active IP Right Cessation
- 1991-06-14 PL PL91290678A patent/PL167177B1/pl not_active IP Right Cessation
- 1991-06-14 TW TW080104715A patent/TW205511B/zh active
- 1991-06-14 TN TNTNSN91047A patent/TNSN91047A1/fr unknown
- 1991-06-14 NZ NZ238543A patent/NZ238543A/en not_active IP Right Cessation
- 1991-06-14 ZA ZA914549A patent/ZA914549B/xx unknown
- 1991-06-14 CN CN91104858A patent/CN1058608C/zh not_active Expired - Fee Related
- 1991-06-14 PH PH42634A patent/PH30243A/en unknown
-
1992
- 1992-02-13 BG BG95911A patent/BG61178B1/bg unknown
- 1992-02-13 NO NO920576A patent/NO302927B1/no not_active IP Right Cessation
- 1992-02-13 NO NO92920576A patent/NO920576L/no unknown
- 1992-02-14 FI FI920661A patent/FI107697B/fi active
-
1993
- 1993-07-14 US US08/094,579 patent/US5643604A/en not_active Expired - Lifetime
-
1995
- 1995-04-17 GR GR950400939T patent/GR3015809T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| IF00 | In force as of 2000-06-30 in czech republic | ||
| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20020613 |