CR8497A - Derivados de azepinoindol como agentes farmaceuticos - Google Patents
Derivados de azepinoindol como agentes farmaceuticosInfo
- Publication number
- CR8497A CR8497A CR8497A CR8497A CR8497A CR 8497 A CR8497 A CR 8497A CR 8497 A CR8497 A CR 8497A CR 8497 A CR8497 A CR 8497A CR 8497 A CR8497 A CR 8497A
- Authority
- CR
- Costa Rica
- Prior art keywords
- azepinoindol
- derivatives
- pharmaceutical agents
- receptors
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Se proporcionan compuestos, composiciones o metodos para modular la actividad de receptores y para el tratamiento, prevencion, o mejora de uno o mas sintomas de enfermedad o trastorno relacionados a la actividad de los receptores.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/895,431 US7595311B2 (en) | 2002-05-24 | 2003-12-02 | Azepinoindole derivatives as pharmaceutical agents |
Publications (1)
Publication Number | Publication Date |
---|---|
CR8497A true CR8497A (es) | 2006-11-17 |
Family
ID=34679499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR8497A CR8497A (es) | 2003-12-02 | 2006-06-28 | Derivados de azepinoindol como agentes farmaceuticos |
Country Status (16)
Country | Link |
---|---|
US (2) | US7595311B2 (es) |
EP (1) | EP1692136A2 (es) |
JP (2) | JP2007513168A (es) |
KR (2) | KR20120091269A (es) |
CN (2) | CN102358741A (es) |
AU (1) | AU2004297198B2 (es) |
BR (1) | BRPI0417260A (es) |
CA (1) | CA2555279C (es) |
CR (1) | CR8497A (es) |
IL (1) | IL176014A0 (es) |
NO (1) | NO20063080L (es) |
NZ (1) | NZ548179A (es) |
RU (1) | RU2423363C2 (es) |
UA (1) | UA86957C2 (es) |
WO (1) | WO2005056554A2 (es) |
ZA (1) | ZA200604352B (es) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
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DE10252667A1 (de) * | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
JP4679517B2 (ja) * | 2003-07-23 | 2011-04-27 | エグゼリクシス, インコーポレイテッド | 薬剤としてのアゼピン誘導体 |
DK1737461T3 (da) | 2004-03-15 | 2013-03-18 | Ptc Therapeutics Inc | Carbolin-derivater til inhibering af angiogenese |
US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
DE102005016460A1 (de) * | 2005-04-11 | 2006-10-19 | Grünenthal GmbH | Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit |
WO2007064634A2 (en) * | 2005-11-30 | 2007-06-07 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Enterostatin as inhibitor of angiogenesis |
US20090203577A1 (en) * | 2005-12-15 | 2009-08-13 | Exelixis, Inc. | Azepinoindole Derivatives As Pharmaceutical Agents |
AU2006329007A1 (en) * | 2005-12-20 | 2007-06-28 | Novartis Ag | Nicotinic acid derivatives as modulators of metabotropic glutamate receptors |
CN101506203B (zh) * | 2006-08-24 | 2013-10-16 | 诺瓦提斯公司 | 治疗代谢病、心血管病和其他病症的作为硬脂酰辅酶a脱饱和酶(scd)抑制剂的2-(吡嗪-2-基)-噻唑和2-(1h-吡唑-3-基)-噻唑衍生物及相关化合物 |
BRPI0718509A2 (pt) * | 2006-09-22 | 2015-09-29 | Novartis Ag | compostos orgânicos heterocíclicos |
CN101595105B (zh) * | 2006-12-20 | 2013-01-23 | 诺瓦提斯公司 | 作为scd抑制剂的2-取代的5元杂环化合物 |
DE102007009235A1 (de) * | 2007-02-22 | 2008-09-18 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
US20080299118A1 (en) * | 2007-06-01 | 2008-12-04 | Wyeth | FXR Agonists for the Treatment of Malignancies |
US20080300235A1 (en) * | 2007-06-01 | 2008-12-04 | Wyeth | FXR Agonists for Reducing LOX-1 Expression |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US20090163474A1 (en) * | 2007-10-19 | 2009-06-25 | Wyeth | FXR Agonists for the Treatment of Nonalcoholic Fatty Liver and Cholesterol Gallstone Diseases |
US20090215748A1 (en) * | 2007-12-20 | 2009-08-27 | Wyeth | FXR agonists for treating vitamin D associated diseases |
US8716308B2 (en) | 2008-01-11 | 2014-05-06 | Albany Molecular Research, Inc. | (1-azinone)-substituted pyridoindoles |
WO2009118174A1 (de) * | 2008-03-27 | 2009-10-01 | Grünenthal GmbH | Substituierte cyclohexyldiamine |
CN102046591B (zh) * | 2008-03-27 | 2014-12-03 | 格吕伦塔尔有限公司 | 羟甲基环己胺 |
EP2502907B1 (de) * | 2008-03-27 | 2018-08-29 | Grünenthal GmbH | Substituierte 4-Aminocyclohexan-Derivate |
SI2260042T1 (sl) * | 2008-03-27 | 2011-11-30 | Gruenenthal Gmbh | Substituirani spirociklični cikloheksanski derivati |
EP2257526B1 (de) | 2008-03-27 | 2011-12-14 | Grünenthal GmbH | Spiro(5.5)undecan derivate |
CA2736880A1 (en) * | 2008-09-26 | 2010-04-01 | Wyeth Llc | 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate nuclear receptor inhibitors |
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KR102000096B1 (ko) * | 2014-12-26 | 2019-07-15 | 후지필름 가부시키가이샤 | 농업 하우스용 필름 및 농업 하우스 |
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US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
TWI329111B (en) * | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
JP4679517B2 (ja) * | 2003-07-23 | 2011-04-27 | エグゼリクシス, インコーポレイテッド | 薬剤としてのアゼピン誘導体 |
-
2003
- 2003-12-02 US US10/895,431 patent/US7595311B2/en not_active Expired - Lifetime
-
2004
- 2004-12-01 KR KR1020127014076A patent/KR20120091269A/ko active IP Right Grant
- 2004-12-01 BR BRPI0417260-4A patent/BRPI0417260A/pt not_active IP Right Cessation
- 2004-12-01 RU RU2006123424/04A patent/RU2423363C2/ru active
- 2004-12-01 CA CA2555279A patent/CA2555279C/en active Active
- 2004-12-01 WO PCT/US2004/040352 patent/WO2005056554A2/en active Application Filing
- 2004-12-01 UA UAA200607302A patent/UA86957C2/ru unknown
- 2004-12-01 AU AU2004297198A patent/AU2004297198B2/en not_active Ceased
- 2004-12-01 EP EP04812795A patent/EP1692136A2/en not_active Withdrawn
- 2004-12-01 NZ NZ548179A patent/NZ548179A/en not_active IP Right Cessation
- 2004-12-01 CN CN2011102439838A patent/CN102358741A/zh active Pending
- 2004-12-01 CN CNA200480041235XA patent/CN1914207A/zh active Pending
- 2004-12-01 JP JP2006542742A patent/JP2007513168A/ja active Pending
-
2006
- 2006-05-29 ZA ZA200604352A patent/ZA200604352B/xx unknown
- 2006-05-30 IL IL176014A patent/IL176014A0/en unknown
- 2006-06-28 CR CR8497A patent/CR8497A/es not_active Application Discontinuation
- 2006-06-30 KR KR1020067013217A patent/KR101270072B1/ko active IP Right Grant
- 2006-07-03 NO NO20063080A patent/NO20063080L/no not_active Application Discontinuation
-
2009
- 2009-08-04 US US12/535,453 patent/US8524704B2/en not_active Expired - Lifetime
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2011
- 2011-06-10 JP JP2011130688A patent/JP2011207907A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
KR20120091269A (ko) | 2012-08-17 |
NO20063080L (no) | 2006-08-23 |
US8524704B2 (en) | 2013-09-03 |
AU2004297198B2 (en) | 2012-02-09 |
RU2006123424A (ru) | 2008-01-10 |
ZA200604352B (en) | 2008-12-31 |
CN102358741A (zh) | 2012-02-22 |
BRPI0417260A (pt) | 2007-03-06 |
KR20060124662A (ko) | 2006-12-05 |
CN1914207A (zh) | 2007-02-14 |
JP2007513168A (ja) | 2007-05-24 |
WO2005056554A2 (en) | 2005-06-23 |
JP2011207907A (ja) | 2011-10-20 |
CA2555279A1 (en) | 2005-06-23 |
WO2005056554A3 (en) | 2005-08-18 |
UA86957C2 (ru) | 2009-06-10 |
US20100173824A1 (en) | 2010-07-08 |
CA2555279C (en) | 2012-10-23 |
KR101270072B1 (ko) | 2013-05-31 |
US7595311B2 (en) | 2009-09-29 |
US20050054634A1 (en) | 2005-03-10 |
NZ548179A (en) | 2009-11-27 |
AU2004297198A1 (en) | 2005-06-23 |
IL176014A0 (en) | 2006-10-05 |
RU2423363C2 (ru) | 2011-07-10 |
EP1692136A2 (en) | 2006-08-23 |
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