CR20230123A - Síntesis de compuestos de quinazolina - Google Patents
Síntesis de compuestos de quinazolinaInfo
- Publication number
- CR20230123A CR20230123A CR20230123A CR20230123A CR20230123A CR 20230123 A CR20230123 A CR 20230123A CR 20230123 A CR20230123 A CR 20230123A CR 20230123 A CR20230123 A CR 20230123A CR 20230123 A CR20230123 A CR 20230123A
- Authority
- CR
- Costa Rica
- Prior art keywords
- synthesis
- quinazoline compounds
- compounds
- quinazoline
- atropisomeric
- Prior art date
Links
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
En la presente se proporcionan métodos para sintetizar compuestos de quinazolina que comprenden al menos un centro atropisomérico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063064746P | 2020-08-12 | 2020-08-12 | |
PCT/US2021/045297 WO2022035790A1 (en) | 2020-08-12 | 2021-08-10 | Synthesis of quinazoline compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20230123A true CR20230123A (es) | 2023-04-19 |
Family
ID=77543703
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20230123A CR20230123A (es) | 2020-08-12 | 2021-08-10 | Síntesis de compuestos de quinazolina |
Country Status (16)
Country | Link |
---|---|
US (1) | US20220081413A1 (es) |
EP (1) | EP4196470A1 (es) |
JP (1) | JP2023537999A (es) |
KR (1) | KR20230049679A (es) |
CN (1) | CN116057052A (es) |
AR (1) | AR123200A1 (es) |
AU (2) | AU2021325869C1 (es) |
BR (1) | BR112023002591A2 (es) |
CA (1) | CA3191001A1 (es) |
CL (1) | CL2023000395A1 (es) |
CR (1) | CR20230123A (es) |
IL (1) | IL300309A (es) |
MX (1) | MX2023001682A (es) |
PE (1) | PE20230733A1 (es) |
TW (1) | TWI829003B (es) |
WO (1) | WO2022035790A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023150706A1 (en) * | 2022-02-07 | 2023-08-10 | Genentech, Inc. | Solid forms of 1-((s)-4-((r)-7-(6-amino-4-methyl-3- (trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((s)-1- methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3- methylpiperazin-1-yl)prop-2-en-1-one |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2727036C (en) | 2008-06-20 | 2017-03-21 | Genentech, Inc. | Triazolopyridine jak inhibitor compounds and methods |
CN105037333A (zh) * | 2009-12-21 | 2015-11-11 | 张强 | 新的喹唑啉衍生物 |
JP2013107855A (ja) * | 2011-11-22 | 2013-06-06 | Mitsubishi Tanabe Pharma Corp | 医薬組成物 |
UA119971C2 (uk) * | 2013-10-10 | 2019-09-10 | Араксіс Фарма Ллк | Інгібітори g12c kras |
WO2017100546A1 (en) * | 2015-12-09 | 2017-06-15 | Araxes Pharma Llc | Methods for preparation of quinazoline derivatives |
CN118084870A (zh) * | 2018-11-09 | 2024-05-28 | 豪夫迈·罗氏有限公司 | 稠环化合物 |
-
2021
- 2021-08-10 US US17/398,345 patent/US20220081413A1/en active Pending
- 2021-08-10 KR KR1020237007998A patent/KR20230049679A/ko unknown
- 2021-08-10 EP EP21762952.6A patent/EP4196470A1/en active Pending
- 2021-08-10 WO PCT/US2021/045297 patent/WO2022035790A1/en active Application Filing
- 2021-08-10 CA CA3191001A patent/CA3191001A1/en active Pending
- 2021-08-10 AR ARP210102232A patent/AR123200A1/es unknown
- 2021-08-10 TW TW110129429A patent/TWI829003B/zh active
- 2021-08-10 PE PE2023000241A patent/PE20230733A1/es unknown
- 2021-08-10 CR CR20230123A patent/CR20230123A/es unknown
- 2021-08-10 JP JP2023509849A patent/JP2023537999A/ja active Pending
- 2021-08-10 AU AU2021325869A patent/AU2021325869C1/en active Active
- 2021-08-10 BR BR112023002591A patent/BR112023002591A2/pt unknown
- 2021-08-10 CN CN202180056371.XA patent/CN116057052A/zh active Pending
- 2021-08-10 IL IL300309A patent/IL300309A/en unknown
- 2021-08-10 MX MX2023001682A patent/MX2023001682A/es unknown
-
2023
- 2023-02-07 CL CL2023000395A patent/CL2023000395A1/es unknown
-
2024
- 2024-01-12 AU AU2024200220A patent/AU2024200220A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20220081413A1 (en) | 2022-03-17 |
EP4196470A1 (en) | 2023-06-21 |
CN116057052A (zh) | 2023-05-02 |
TW202214596A (zh) | 2022-04-16 |
WO2022035790A1 (en) | 2022-02-17 |
CA3191001A1 (en) | 2022-02-17 |
CL2023000395A1 (es) | 2023-07-28 |
JP2023537999A (ja) | 2023-09-06 |
KR20230049679A (ko) | 2023-04-13 |
AU2024200220A1 (en) | 2024-02-01 |
MX2023001682A (es) | 2023-02-22 |
TWI829003B (zh) | 2024-01-11 |
AR123200A1 (es) | 2022-11-09 |
AU2021325869A1 (en) | 2023-02-23 |
AU2021325869C1 (en) | 2024-05-30 |
BR112023002591A2 (pt) | 2023-04-04 |
IL300309A (en) | 2023-04-01 |
PE20230733A1 (es) | 2023-05-03 |
AU2021325869B2 (en) | 2024-02-15 |
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