CR20220280A - Terapia de combinación que comprende un inhibidor de alk2 y un inhibidor de jak2 - Google Patents
Terapia de combinación que comprende un inhibidor de alk2 y un inhibidor de jak2Info
- Publication number
- CR20220280A CR20220280A CR20220280A CR20220280A CR20220280A CR 20220280 A CR20220280 A CR 20220280A CR 20220280 A CR20220280 A CR 20220280A CR 20220280 A CR20220280 A CR 20220280A CR 20220280 A CR20220280 A CR 20220280A
- Authority
- CR
- Costa Rica
- Prior art keywords
- inhibitor
- alk2
- combination therapy
- jak2
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En el presente documento se proporcionan compuestos, composiciones farmacéuticas que comprenden dichos compuestosy métodos para usar dichos compustos para tratar enfermedades o transtornos asociados con JAK/2 y/o ALK2.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962939241P | 2019-11-22 | 2019-11-22 | |
US202062980562P | 2020-02-24 | 2020-02-24 | |
US202063035194P | 2020-06-05 | 2020-06-05 | |
US202063056768P | 2020-07-27 | 2020-07-27 | |
PCT/US2020/061497 WO2021102258A1 (en) | 2019-11-22 | 2020-11-20 | Combination therapy comprising an alk2 inhibitor and a jak2 inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20220280A true CR20220280A (es) | 2022-09-02 |
Family
ID=73699492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20220280A CR20220280A (es) | 2019-11-22 | 2020-11-20 | Terapia de combinación que comprende un inhibidor de alk2 y un inhibidor de jak2 |
Country Status (16)
Country | Link |
---|---|
US (2) | US11738026B2 (es) |
EP (1) | EP4061367A1 (es) |
JP (1) | JP2023502742A (es) |
KR (1) | KR20220107213A (es) |
CN (1) | CN115038443A (es) |
AU (1) | AU2020388638A1 (es) |
BR (1) | BR112022009710A2 (es) |
CA (1) | CA3160312A1 (es) |
CL (1) | CL2022001325A1 (es) |
CR (1) | CR20220280A (es) |
EC (1) | ECSP22044525A (es) |
IL (1) | IL293085A (es) |
MX (1) | MX2022006176A (es) |
PE (1) | PE20230251A1 (es) |
TW (1) | TW202131926A (es) |
WO (1) | WO2021102258A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW202214239A (zh) | 2020-06-16 | 2022-04-16 | 美商英塞特公司 | 用於治療貧血之alk2抑制劑 |
WO2023081212A1 (en) * | 2021-11-02 | 2023-05-11 | Keros Therapeutics, Inc. | Methods of using alk2 inhibitors |
CN116478145B (zh) * | 2022-04-13 | 2024-02-02 | 杭州邦顺制药有限公司 | Alk2激酶抑制剂 |
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2020
- 2020-11-20 IL IL293085A patent/IL293085A/en unknown
- 2020-11-20 MX MX2022006176A patent/MX2022006176A/es unknown
- 2020-11-20 TW TW109140802A patent/TW202131926A/zh unknown
- 2020-11-20 EP EP20820023.8A patent/EP4061367A1/en active Pending
- 2020-11-20 JP JP2022529824A patent/JP2023502742A/ja active Pending
- 2020-11-20 WO PCT/US2020/061497 patent/WO2021102258A1/en unknown
- 2020-11-20 CN CN202080094112.1A patent/CN115038443A/zh active Pending
- 2020-11-20 KR KR1020227020597A patent/KR20220107213A/ko unknown
- 2020-11-20 CA CA3160312A patent/CA3160312A1/en active Pending
- 2020-11-20 BR BR112022009710A patent/BR112022009710A2/pt unknown
- 2020-11-20 AU AU2020388638A patent/AU2020388638A1/en active Pending
- 2020-11-20 CR CR20220280A patent/CR20220280A/es unknown
- 2020-11-20 US US16/953,989 patent/US11738026B2/en active Active
- 2020-11-20 PE PE2022000820A patent/PE20230251A1/es unknown
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2022
- 2022-05-19 CL CL2022001325A patent/CL2022001325A1/es unknown
- 2022-06-03 EC ECSENADI202244525A patent/ECSP22044525A/es unknown
-
2023
- 2023-07-12 US US18/351,278 patent/US20240041887A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2023502742A (ja) | 2023-01-25 |
CA3160312A1 (en) | 2021-05-27 |
PE20230251A1 (es) | 2023-02-07 |
IL293085A (en) | 2022-07-01 |
US20210154195A1 (en) | 2021-05-27 |
TW202131926A (zh) | 2021-09-01 |
BR112022009710A2 (pt) | 2022-08-09 |
WO2021102258A1 (en) | 2021-05-27 |
CN115038443A (zh) | 2022-09-09 |
ECSP22044525A (es) | 2022-08-31 |
EP4061367A1 (en) | 2022-09-28 |
AU2020388638A1 (en) | 2022-06-30 |
CL2022001325A1 (es) | 2023-03-24 |
KR20220107213A (ko) | 2022-08-02 |
US11738026B2 (en) | 2023-08-29 |
US20240041887A1 (en) | 2024-02-08 |
MX2022006176A (es) | 2022-08-17 |
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