CR20170106A - Compuestos de 1-alquil-6-oxo-1, 6-dihidropiridin-3-ilo y usos de los mismos - Google Patents

Compuestos de 1-alquil-6-oxo-1, 6-dihidropiridin-3-ilo y usos de los mismos

Info

Publication number
CR20170106A
CR20170106A CR20170106A CR20170106A CR20170106A CR 20170106 A CR20170106 A CR 20170106A CR 20170106 A CR20170106 A CR 20170106A CR 20170106 A CR20170106 A CR 20170106A CR 20170106 A CR20170106 A CR 20170106A
Authority
CR
Costa Rica
Prior art keywords
compounds
oxo
dihidropiridin
alquil
ilo
Prior art date
Application number
CR20170106A
Other languages
English (en)
Inventor
Matti Juhani Lepistö
Antonio Llinas
Lena Elisabeth Ripa
Karolina Lawitz
Martin Hemmerling
Karl Edman
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54252264&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20170106(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CR20170106A publication Critical patent/CR20170106A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere en forma general a los compuestos de 1-alquil-6-oxo-1,6-dihidropiridin-3-ilo (incluyendo sales de los mismos). La presente invención asimismo se refiere a las composiciones farmacéuticas y a los kits que comprenden dichos compuestos, a los usos de dichos compuestos (incluyendo métodos de tratamiento y preparación de medicamentos), y a los procesos para preparar dichos compuestos
CR20170106A 2014-09-26 2015-09-23 Compuestos de 1-alquil-6-oxo-1, 6-dihidropiridin-3-ilo y usos de los mismos CR20170106A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462055822P 2014-09-26 2014-09-26
PCT/EP2015/071862 WO2016046260A1 (en) 2014-09-26 2015-09-23 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators

Publications (1)

Publication Number Publication Date
CR20170106A true CR20170106A (es) 2017-09-01

Family

ID=54252264

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20170106A CR20170106A (es) 2014-09-26 2015-09-23 Compuestos de 1-alquil-6-oxo-1, 6-dihidropiridin-3-ilo y usos de los mismos

Country Status (30)

Country Link
US (1) US10196374B2 (es)
EP (1) EP3197878B1 (es)
JP (1) JP6430000B2 (es)
KR (1) KR101866706B1 (es)
CN (1) CN107001320B (es)
AP (1) AP2017009819A0 (es)
AR (1) AR105549A1 (es)
AU (1) AU2015323817B2 (es)
BR (1) BR112017006085B1 (es)
CA (1) CA2962312C (es)
CL (1) CL2017000715A1 (es)
CO (1) CO2017003955A2 (es)
CR (1) CR20170106A (es)
DO (1) DOP2017000064A (es)
EA (1) EA031945B1 (es)
ES (1) ES2751640T3 (es)
GT (1) GT201700058A (es)
IL (1) IL250886A0 (es)
MX (1) MX2017003697A (es)
NI (1) NI201700038A (es)
NZ (1) NZ730250A (es)
PE (1) PE20171110A1 (es)
PH (1) PH12017500533A1 (es)
SG (1) SG11201702225VA (es)
SV (1) SV2017005412A (es)
TN (1) TN2017000096A1 (es)
TW (1) TW201619146A (es)
UY (1) UY36327A (es)
WO (1) WO2016046260A1 (es)
ZA (1) ZA201702720B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017161518A1 (en) * 2016-03-23 2017-09-28 Astrazeneca Ab New physical form
TW201927769A (zh) 2017-12-18 2019-07-16 德商歌林達有限公司 經取代之吡咯啶醯胺ｉｉ
EP3728219B1 (en) 2017-12-18 2022-04-13 Grünenthal GmbH Substituted pyrrolidine amides i
TWI827785B (zh) 2019-01-11 2024-01-01 德商歌林達有限公司 經取代的吡咯啶醯胺iii
WO2020254551A1 (en) 2019-06-19 2020-12-24 Grünenthal GmbH Substituted pyrrolidine amides iv
WO2020254552A2 (en) 2019-06-19 2020-12-24 Grünenthal GmbH Substituted pyrrolidine amides v
EP4086247A4 (en) * 2019-12-31 2023-12-06 Medshine Discovery Inc. BENZOPYRAZOLE COMPOUND
US20230265078A1 (en) 2020-07-09 2023-08-24 Gruenenthal Gmbh Substituted pyrrolidine amines and amides vi
CN115667237A (zh) * 2020-07-17 2023-01-31 成都苑东生物制药股份有限公司 作为bet抑制剂的新型杂环化合物
WO2023041695A1 (en) 2021-09-20 2023-03-23 Astrazeneca Ab Methods of treating inflammatory diseases with a selective glucocorticoid receptor modulator

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007000615A (es) * 2004-07-16 2007-03-07 Janssen Pharmaceutica Nv Compuestos dimericos de piperidina, piperazina o morfolina o sus analogos de 7 miembros adecuados para el tratamiento de trastornos neurodegenerativos.
JO2754B1 (en) * 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
TW200951114A (en) * 2008-05-20 2009-12-16 Astrazeneca Ab Phenyl or pyridinyl substituted indazoles derivatives

Also Published As

Publication number Publication date
KR101866706B1 (ko) 2018-06-11
CO2017003955A2 (es) 2017-05-10
WO2016046260A1 (en) 2016-03-31
NZ730250A (en) 2018-03-23
US20170298041A1 (en) 2017-10-19
AU2015323817A1 (en) 2017-04-06
PE20171110A1 (es) 2017-08-07
BR112017006085B1 (pt) 2023-03-07
TN2017000096A1 (en) 2018-07-04
JP6430000B2 (ja) 2018-11-28
CA2962312C (en) 2019-01-15
MX2017003697A (es) 2017-06-26
DOP2017000064A (es) 2017-03-31
WO2016046260A8 (en) 2017-04-13
UY36327A (es) 2016-04-01
TW201619146A (zh) 2016-06-01
EP3197878B1 (en) 2019-07-24
KR20170042785A (ko) 2017-04-19
EP3197878A1 (en) 2017-08-02
CA2962312A1 (en) 2016-03-31
BR112017006085A2 (pt) 2017-12-19
IL250886A0 (en) 2017-04-30
SG11201702225VA (en) 2017-04-27
US10196374B2 (en) 2019-02-05
GT201700058A (es) 2019-08-12
EA201790496A1 (ru) 2018-03-30
JP2017529369A (ja) 2017-10-05
PH12017500533A1 (en) 2017-08-07
AP2017009819A0 (en) 2017-03-31
AR105549A1 (es) 2017-10-18
SV2017005412A (es) 2017-10-23
CN107001320A (zh) 2017-08-01
AU2015323817B2 (en) 2018-11-01
EA031945B1 (ru) 2019-03-29
ZA201702720B (en) 2019-06-26
ES2751640T3 (es) 2020-04-01
NI201700038A (es) 2018-01-05
CL2017000715A1 (es) 2017-11-10
CN107001320B (zh) 2019-09-20

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