SG11201702225VA - 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators - Google Patents

1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators

Info

Publication number
SG11201702225VA
SG11201702225VA SG11201702225VA SG11201702225VA SG11201702225VA SG 11201702225V A SG11201702225V A SG 11201702225VA SG 11201702225V A SG11201702225V A SG 11201702225VA SG 11201702225V A SG11201702225V A SG 11201702225VA SG 11201702225V A SG11201702225V A SG 11201702225VA
Authority
SG
Singapore
Prior art keywords
sgrm
dihydropyridin
modulators
oxo
alkyl
Prior art date
Application number
SG11201702225VA
Other languages
English (en)
Inventor
Lena Elisabeth Ripa
Karolina Lawitz
Matti Juhani Lepistö
Martin Hemmerling
Karl Edman
Antonio Llinas
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54252264&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201702225V(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SG11201702225VA publication Critical patent/SG11201702225VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201702225VA 2014-09-26 2015-09-23 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators SG11201702225VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462055822P 2014-09-26 2014-09-26
PCT/EP2015/071862 WO2016046260A1 (en) 2014-09-26 2015-09-23 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators

Publications (1)

Publication Number Publication Date
SG11201702225VA true SG11201702225VA (en) 2017-04-27

Family

ID=54252264

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702225VA SG11201702225VA (en) 2014-09-26 2015-09-23 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as sgrm modulators

Country Status (30)

Country Link
US (1) US10196374B2 (es)
EP (1) EP3197878B1 (es)
JP (1) JP6430000B2 (es)
KR (1) KR101866706B1 (es)
CN (1) CN107001320B (es)
AP (1) AP2017009819A0 (es)
AR (1) AR105549A1 (es)
AU (1) AU2015323817B2 (es)
BR (1) BR112017006085B1 (es)
CA (1) CA2962312C (es)
CL (1) CL2017000715A1 (es)
CO (1) CO2017003955A2 (es)
CR (1) CR20170106A (es)
DO (1) DOP2017000064A (es)
EA (1) EA031945B1 (es)
ES (1) ES2751640T3 (es)
GT (1) GT201700058A (es)
IL (1) IL250886A0 (es)
MX (1) MX2017003697A (es)
NI (1) NI201700038A (es)
NZ (1) NZ730250A (es)
PE (1) PE20171110A1 (es)
PH (1) PH12017500533A1 (es)
SG (1) SG11201702225VA (es)
SV (1) SV2017005412A (es)
TN (1) TN2017000096A1 (es)
TW (1) TW201619146A (es)
UY (1) UY36327A (es)
WO (1) WO2016046260A1 (es)
ZA (1) ZA201702720B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017161518A1 (en) * 2016-03-23 2017-09-28 Astrazeneca Ab New physical form
TW201927769A (zh) 2017-12-18 2019-07-16 德商歌林達有限公司 經取代之吡咯啶醯胺ii
ES2925198T3 (es) 2017-12-18 2022-10-14 Gruenenthal Gmbh Amidas de pirrolidinas sustituidas I
US20220089573A1 (en) 2019-01-11 2022-03-24 Grünenthal GmbH Substituted pyrrolidine amides iii
EP3986886A2 (en) 2019-06-19 2022-04-27 Grünenthal GmbH Substituted pyrrolidine amides v
WO2020254551A1 (en) 2019-06-19 2020-12-24 Grünenthal GmbH Substituted pyrrolidine amides iv
WO2021136429A1 (zh) * 2019-12-31 2021-07-08 南京明德新药研发有限公司 苯并吡唑类化合物
EP4178954A1 (en) 2020-07-09 2023-05-17 Grünenthal GmbH Substituted pyrrolidine amines and amides as mediator of the glucocortoid receptor
CN115667237A (zh) * 2020-07-17 2023-01-31 成都苑东生物制药股份有限公司 作为bet抑制剂的新型杂环化合物
WO2023041695A1 (en) 2021-09-20 2023-03-23 Astrazeneca Ab Methods of treating inflammatory diseases with a selective glucocorticoid receptor modulator

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA200700140A1 (ru) * 2004-07-16 2007-08-31 Янссен Фармацевтика Н.В. Димерные соединения пиперидина, пиперазина или морфолина или их семичленные аналоги, предназначенные для лечения нейродегенеративных нарушений
JO2754B1 (en) * 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
SA109300309B1 (ar) * 2008-05-20 2013-01-22 باير شيرنج فارما ايه جي مشتقات فينيل وبنزو داي أوكسينيل إندازول بها استبدال

Also Published As

Publication number Publication date
EP3197878B1 (en) 2019-07-24
CN107001320B (zh) 2019-09-20
ES2751640T3 (es) 2020-04-01
AP2017009819A0 (en) 2017-03-31
JP2017529369A (ja) 2017-10-05
WO2016046260A1 (en) 2016-03-31
DOP2017000064A (es) 2017-03-31
CL2017000715A1 (es) 2017-11-10
GT201700058A (es) 2019-08-12
US20170298041A1 (en) 2017-10-19
TN2017000096A1 (en) 2018-07-04
ZA201702720B (en) 2019-06-26
SV2017005412A (es) 2017-10-23
CO2017003955A2 (es) 2017-05-10
JP6430000B2 (ja) 2018-11-28
IL250886A0 (en) 2017-04-30
UY36327A (es) 2016-04-01
BR112017006085A2 (pt) 2017-12-19
CR20170106A (es) 2017-09-01
MX2017003697A (es) 2017-06-26
PE20171110A1 (es) 2017-08-07
TW201619146A (zh) 2016-06-01
EA201790496A1 (ru) 2018-03-30
BR112017006085B1 (pt) 2023-03-07
US10196374B2 (en) 2019-02-05
EP3197878A1 (en) 2017-08-02
AU2015323817A1 (en) 2017-04-06
NI201700038A (es) 2018-01-05
KR101866706B1 (ko) 2018-06-11
CA2962312C (en) 2019-01-15
CN107001320A (zh) 2017-08-01
PH12017500533A1 (en) 2017-08-07
NZ730250A (en) 2018-03-23
WO2016046260A8 (en) 2017-04-13
AR105549A1 (es) 2017-10-18
EA031945B1 (ru) 2019-03-29
KR20170042785A (ko) 2017-04-19
CA2962312A1 (en) 2016-03-31
AU2015323817B2 (en) 2018-11-01

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