CR11146A - Antagonistas piridil piperidina del receptor de orexina - Google Patents
Antagonistas piridil piperidina del receptor de orexinaInfo
- Publication number
- CR11146A CR11146A CR11146A CR11146A CR11146A CR 11146 A CR11146 A CR 11146A CR 11146 A CR11146 A CR 11146A CR 11146 A CR11146 A CR 11146A CR 11146 A CR11146 A CR 11146A
- Authority
- CR
- Costa Rica
- Prior art keywords
- orexina
- antigonistas
- piperidina
- piridil
- receiver
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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Abstract
La presente invencion se refiere a compuestos de piridil piperidina que son antagonistas de los receptores de orexina y que son utiles en el tratamiento o prevencion de trastornos y enfermedades neurologicas y psiquiatricas en las que estan implicados los receptores de orexina. La invencion tambien se refiere a composiciones farmaceuticas que comprenden estos compuestos y al uso de estos compuestos y composiciones en la prevencion o tratamiento de dichas enfermedades en las que estan implicados los receptores de orexina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93145807P | 2007-05-23 | 2007-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR11146A true CR11146A (es) | 2010-03-01 |
Family
ID=39708485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR11146A CR11146A (es) | 2007-05-23 | 2009-12-04 | Antagonistas piridil piperidina del receptor de orexina |
Country Status (34)
Country | Link |
---|---|
US (2) | US8242121B2 (es) |
EP (1) | EP2152690B1 (es) |
JP (2) | JP4881476B2 (es) |
KR (1) | KR101480279B1 (es) |
CN (1) | CN101679366B (es) |
AT (1) | ATE540944T1 (es) |
AU (1) | AU2008257411B2 (es) |
BR (1) | BRPI0811842A2 (es) |
CA (1) | CA2687321C (es) |
CO (1) | CO6251266A2 (es) |
CR (1) | CR11146A (es) |
CY (1) | CY1112969T1 (es) |
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GB0823467D0 (en) | 2008-12-23 | 2009-01-28 | Glaxo Group Ltd | Novel Compounds |
WO2011023578A1 (en) | 2009-08-24 | 2011-03-03 | Glaxo Group Limited | 5-methyl-piperidine derivatives as orexin receptor antagonists for the treatment of sleep disorder |
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