DK3336088T3 - Krystalform af orexinreceptorantagonistforbindelse, og fremgangsmåde til fremstilling og anvendelse af denne - Google Patents
Krystalform af orexinreceptorantagonistforbindelse, og fremgangsmåde til fremstilling og anvendelse af denne Download PDFInfo
- Publication number
- DK3336088T3 DK3336088T3 DK16836596.3T DK16836596T DK3336088T3 DK 3336088 T3 DK3336088 T3 DK 3336088T3 DK 16836596 T DK16836596 T DK 16836596T DK 3336088 T3 DK3336088 T3 DK 3336088T3
- Authority
- DK
- Denmark
- Prior art keywords
- making
- same
- receptor antagonist
- crystal form
- antagonist compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510501331 | 2015-08-14 | ||
| PCT/CN2016/094558 WO2017028732A1 (zh) | 2015-08-14 | 2016-08-11 | 食欲素受体拮抗剂化合物的晶型及其制备方法和应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3336088T3 true DK3336088T3 (da) | 2021-06-28 |
Family
ID=58050753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16836596.3T DK3336088T3 (da) | 2015-08-14 | 2016-08-11 | Krystalform af orexinreceptorantagonistforbindelse, og fremgangsmåde til fremstilling og anvendelse af denne |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10668066B2 (da) |
| EP (1) | EP3336088B1 (da) |
| JP (1) | JP6772251B2 (da) |
| CN (3) | CN111499625B (da) |
| DK (1) | DK3336088T3 (da) |
| TW (1) | TWI631122B (da) |
| WO (1) | WO2017028732A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021208976A1 (zh) | 2020-04-17 | 2021-10-21 | 上海海雁医药科技有限公司 | 固体药物制剂及其制备方法和用途 |
| CN112480107B (zh) * | 2020-11-30 | 2022-08-16 | 上海海雁医药科技有限公司 | 取代的氮杂双环辛烷化合物及其中间体和制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| NZ580887A (en) * | 2007-05-23 | 2012-03-30 | Merck Sharp & Dohme | Pyridyl piperidine orexin receptor antagonists |
| WO2009104155A1 (en) * | 2008-02-21 | 2009-08-27 | Actelion Pharmaceuticals Ltd | 2-aza-bicyclo[2.2.1]heptane derivatives |
| MX2010013447A (es) * | 2008-06-18 | 2010-12-22 | Hoffmann La Roche | Aril-cetonas como inhibidores de reabsorcion de monoaminas. |
| WO2014059591A1 (en) * | 2012-10-16 | 2014-04-24 | Broadcom Corporation | Initial access for standalone carrier type |
| TWI621618B (zh) * | 2013-03-13 | 2018-04-21 | 比利時商健生藥品公司 | 經取代２－氮雜雙環類及其作為食慾素受體調控劑之用途 |
| TW201444849A (zh) * | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途 |
| JP6262885B2 (ja) * | 2014-03-06 | 2018-01-17 | シャンハイ ハイヤン ファーマシューティカル テクノロジー カンパニー リミテッドＳｈａｎｇｈａｉ Ｈａｉｙａｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏ．， Ｌｔｄ． | オレキシン受容体拮抗剤としてのピペリジン誘導体 |
-
2016
- 2016-08-11 EP EP16836596.3A patent/EP3336088B1/en active Active
- 2016-08-11 JP JP2018507552A patent/JP6772251B2/ja active Active
- 2016-08-11 US US15/752,290 patent/US10668066B2/en active Active
- 2016-08-11 CN CN202010591921.5A patent/CN111499625B/zh active Active
- 2016-08-11 DK DK16836596.3T patent/DK3336088T3/da active
- 2016-08-11 CN CN201680017909.5A patent/CN107709318B/zh active Active
- 2016-08-11 CN CN202010948889.1A patent/CN111848603B/zh active Active
- 2016-08-11 WO PCT/CN2016/094558 patent/WO2017028732A1/zh active Application Filing
- 2016-08-12 TW TW105125792A patent/TWI631122B/zh active
-
2020
- 2020-04-30 US US16/864,153 patent/US10898486B2/en active Active
- 2020-04-30 US US16/864,020 patent/US10874674B2/en active Active
- 2020-04-30 US US16/864,148 patent/US10912775B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200253972A1 (en) | 2020-08-13 |
| US10668066B2 (en) | 2020-06-02 |
| US20200261453A1 (en) | 2020-08-20 |
| JP2018525395A (ja) | 2018-09-06 |
| CN111848603B (zh) | 2022-08-09 |
| EP3336088A4 (en) | 2019-03-13 |
| CN107709318A (zh) | 2018-02-16 |
| CN107709318B (zh) | 2020-09-25 |
| WO2017028732A1 (zh) | 2017-02-23 |
| US10874674B2 (en) | 2020-12-29 |
| EP3336088B1 (en) | 2021-04-21 |
| US10912775B2 (en) | 2021-02-09 |
| JP6772251B2 (ja) | 2020-10-21 |
| US20180235965A1 (en) | 2018-08-23 |
| US20200261452A1 (en) | 2020-08-20 |
| CN111499625B (zh) | 2022-09-02 |
| TW201710260A (zh) | 2017-03-16 |
| TWI631122B (zh) | 2018-08-01 |
| CN111848603A (zh) | 2020-10-30 |
| US10898486B2 (en) | 2021-01-26 |
| EP3336088A1 (en) | 2018-06-20 |
| CN111499625A (zh) | 2020-08-07 |
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