CO6801799A2 - Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios - Google Patents

Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios

Info

Publication number
CO6801799A2
CO6801799A2 CO13252979A CO13252979A CO6801799A2 CO 6801799 A2 CO6801799 A2 CO 6801799A2 CO 13252979 A CO13252979 A CO 13252979A CO 13252979 A CO13252979 A CO 13252979A CO 6801799 A2 CO6801799 A2 CO 6801799A2
Authority
CO
Colombia
Prior art keywords
depsypeptides
macrocyclic
elaboration
processes
new intermediaries
Prior art date
Application number
CO13252979A
Other languages
English (en)
Inventor
Murat Acemoglu
Felix Kollmer
John Lopez
Robert Schreiber
Christian Sprecher
Hans Stettler
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46317455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6801799(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO6801799A2 publication Critical patent/CO6801799A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cookers (AREA)
  • Cereal-Derived Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CO13252979A 2011-04-20 2013-10-24 Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios CO6801799A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161477319P 2011-04-20 2011-04-20

Publications (1)

Publication Number Publication Date
CO6801799A2 true CO6801799A2 (es) 2013-11-29

Family

ID=46317455

Family Applications (1)

Application Number Title Priority Date Filing Date
CO13252979A CO6801799A2 (es) 2011-04-20 2013-10-24 Procesos para la elaboración de depsipéptidos macrocíclicos y nuevos intermediarios

Country Status (21)

Country Link
US (2) US8614289B2 (es)
EP (1) EP2699585A1 (es)
JP (2) JP5951006B2 (es)
KR (1) KR101580729B1 (es)
CN (2) CN104804072A (es)
AR (1) AR086168A1 (es)
AU (1) AU2012245980B2 (es)
BR (1) BR112013026660A2 (es)
CA (1) CA2833109A1 (es)
CL (2) CL2013003037A1 (es)
CO (1) CO6801799A2 (es)
EA (2) EA025546B1 (es)
GT (1) GT201300256A (es)
IL (1) IL228727A0 (es)
MA (1) MA35034B1 (es)
MX (1) MX337526B (es)
PE (1) PE20141206A1 (es)
SG (1) SG193918A1 (es)
TN (1) TN2013000385A1 (es)
TW (1) TW201249863A (es)
WO (1) WO2012143888A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008290567B2 (en) 2007-08-17 2011-05-12 Novartis Ag Cyclic depsipeptides
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
AR086168A1 (es) 2011-04-20 2013-11-27 Novartis Ag Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) * 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
CN106029684A (zh) 2014-04-08 2016-10-12 诺华股份有限公司 用于生产大环缩酚酸肽和新中间体的新型缩醛类方法
JP7045191B2 (ja) * 2015-05-20 2022-03-31 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性デプシペプチド化合物
WO2017049128A1 (en) 2015-09-17 2017-03-23 Massachusetts Institute Of Technology Methods and systems for solid phase peptide synthesis
KR102031186B1 (ko) * 2017-01-11 2019-11-08 주식회사 엘지생활건강 단백질 강도 강화용 조성물
US11643438B2 (en) 2018-07-20 2023-05-09 The Board Of Regents Of The University Of Oklahoma Antimicrobial peptides and methods of use

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3043252C2 (de) 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
DE4421113A1 (de) 1994-06-16 1995-12-21 Biotechnolog Forschung Gmbh Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung
DE19828043A1 (de) 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
JP2000154198A (ja) 1998-11-20 2000-06-06 Nisshin Flour Milling Co Ltd 環状デプシペプチドの固相合成方法及びその中間体
GB0108234D0 (en) * 2001-04-02 2001-05-23 Pharma Mar Sa Process for producing trunkamide A compounds
US20040110228A1 (en) 2002-04-01 2004-06-10 Mcalpine Shelli R. Combinatorial organic synthesis of unique biologically active compounds
CA2525383C (en) 2003-06-06 2012-03-06 Arexis Ab Use of heterocyclic compounds as scce inhibitors
GB0322140D0 (en) 2003-09-22 2003-10-22 Pfizer Ltd Combinations
WO2005075667A1 (en) 2004-02-03 2005-08-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
EP1994181A4 (en) 2006-02-27 2010-05-19 Univ Arizona IDENTIFICATION AND USE OF NOVOPEPTIDES FOR THE TREATMENT OF CANCER
GB0715750D0 (en) 2007-08-13 2007-09-19 Karus Therapeutics Ltd Chemical compounds
JP5401459B2 (ja) 2007-08-17 2014-01-29 ノバルティス アーゲー カリクレイン７を阻害するための環状デプシペプチドの使用
AU2008290567B2 (en) 2007-08-17 2011-05-12 Novartis Ag Cyclic depsipeptides
DE102007052391A1 (de) 2007-10-31 2009-05-07 Henkel Ag & Co. Kgaa Mattwachs
US20110112121A1 (en) 2009-07-06 2011-05-12 Joerg Berghausen Pharmaceutical Compositions and Solid Forms
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 ＴＮＦ－α와 ＴＷＥＡＫ 이중 길항제
US20120064136A1 (en) 2010-09-10 2012-03-15 Nanobio Corporation Anti-aging and wrinkle treatment methods using nanoemulsion compositions
EP2616037A2 (en) 2010-09-14 2013-07-24 Trima - Israel Phramaceutical Products Maabarot Ltd. Foamable topical composition
KR20140003572A (ko) 2011-01-24 2014-01-09 안테리오스, 인코퍼레이티드 나노입자 조성물
IL293156A (en) 2011-01-24 2022-07-01 Anterios Inc Nanoparticle compounds, their formulations, and their use
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
AR086168A1 (es) 2011-04-20 2013-11-27 Novartis Ag Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
CN106029684A (zh) 2014-04-08 2016-10-12 诺华股份有限公司 用于生产大环缩酚酸肽和新中间体的新型缩醛类方法

Also Published As

Publication number Publication date
BR112013026660A2 (pt) 2016-09-06
PE20141206A1 (es) 2014-09-28
TW201249863A (en) 2012-12-16
EA201391554A1 (ru) 2014-11-28
JP5951006B2 (ja) 2016-07-13
US20140080995A1 (en) 2014-03-20
EA201500734A1 (ru) 2015-11-30
KR101580729B1 (ko) 2015-12-28
KR20130140204A (ko) 2013-12-23
MA35034B1 (fr) 2014-04-03
GT201300256A (es) 2015-02-19
CL2013003037A1 (es) 2014-10-03
AR086168A1 (es) 2013-11-27
CN104804072A (zh) 2015-07-29
TN2013000385A1 (en) 2015-01-20
WO2012143888A1 (en) 2012-10-26
MX2013012188A (es) 2013-11-04
CN103476789B (zh) 2016-11-09
US8614289B2 (en) 2013-12-24
MX337526B (es) 2016-03-09
CA2833109A1 (en) 2012-10-26
EP2699585A1 (en) 2014-02-26
US20120277406A1 (en) 2012-11-01
CL2015000688A1 (es) 2015-06-05
SG193918A1 (en) 2013-11-29
EA025546B1 (ru) 2017-01-30
JP2014511899A (ja) 2014-05-19
CN103476789A (zh) 2013-12-25
US9278997B2 (en) 2016-03-08
JP2016164158A (ja) 2016-09-08
AU2012245980B2 (en) 2015-01-29
AU2012245980A1 (en) 2013-10-03
IL228727A0 (en) 2013-12-31

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