CO6640262A2 - Composiciones farmacéuticas y métodos para su elaboración - Google Patents
Composiciones farmacéuticas y métodos para su elaboraciónInfo
- Publication number
- CO6640262A2 CO6640262A2 CO12221016A CO12221016A CO6640262A2 CO 6640262 A2 CO6640262 A2 CO 6640262A2 CO 12221016 A CO12221016 A CO 12221016A CO 12221016 A CO12221016 A CO 12221016A CO 6640262 A2 CO6640262 A2 CO 6640262A2
- Authority
- CO
- Colombia
- Prior art keywords
- methods
- pharmaceutical compositions
- preparation
- pazopanib
- weight
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describen composiciones farmacéuticas que incluyen una cantidad de una sal de adición de ácido de pazopanib equivalente a 10 miligramos/mililitro de pazopanib, y del 2 al 13 por ciento en peso/peso de una ciclodextrina modificada adecuada para utilizarse en una formulación oftálmica, así como métodos para la elaboración de las mismas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33171510P | 2010-05-05 | 2010-05-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6640262A2 true CO6640262A2 (es) | 2013-03-22 |
Family
ID=44851507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO12221016A CO6640262A2 (es) | 2010-05-05 | 2012-12-05 | Composiciones farmacéuticas y métodos para su elaboración |
Country Status (26)
Country | Link |
---|---|
US (3) | US20120028918A1 (es) |
EP (1) | EP2566331B1 (es) |
JP (1) | JP5835717B2 (es) |
KR (1) | KR20130071434A (es) |
CN (1) | CN102970871A (es) |
AR (1) | AR081364A1 (es) |
AU (1) | AU2011247995B2 (es) |
BR (1) | BR112012028291A2 (es) |
CA (1) | CA2798386A1 (es) |
CL (1) | CL2012003075A1 (es) |
CO (1) | CO6640262A2 (es) |
CR (1) | CR20120556A (es) |
DO (1) | DOP2012000281A (es) |
EA (1) | EA201291168A1 (es) |
ES (1) | ES2519615T3 (es) |
HK (1) | HK1175947A1 (es) |
IL (1) | IL222751A0 (es) |
MA (1) | MA34286B1 (es) |
MX (1) | MX2012012837A (es) |
NZ (1) | NZ603411A (es) |
PE (1) | PE20130217A1 (es) |
SG (1) | SG185087A1 (es) |
TW (1) | TW201206908A (es) |
UY (1) | UY33367A (es) |
WO (1) | WO2011140343A1 (es) |
ZA (1) | ZA201208265B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
ES2493641T3 (es) * | 2007-06-28 | 2014-09-12 | Cydex Pharmaceuticals, Inc. | Administración nasal de soluciones acuosas de corticosteroides |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
UY33367A (es) * | 2010-05-05 | 2011-10-31 | Glaxo Wellcome Mfg Pte Ltd | Composiciones farmacéuticas y métodos para su elaboración |
SI2600930T1 (sl) | 2010-08-05 | 2021-08-31 | Forsight Vision4, Inc. | Injekcijska naprava za dajanje zdravila |
WO2012068549A2 (en) | 2010-11-19 | 2012-05-24 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
US9883968B2 (en) | 2011-09-16 | 2018-02-06 | Forsight Vision4, Inc. | Fluid exchange apparatus and methods |
CA2864736A1 (en) * | 2012-02-17 | 2013-08-22 | Pharmacyclics, Inc. | Combinations of histone deacetylase inhibitor and pazopanib and uses thereof |
EP2824981B1 (en) * | 2012-03-08 | 2019-02-27 | Samsung Electronics Co., Ltd. | Method for controlling service in radio communication system |
WO2014152959A1 (en) * | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
EP4302736A3 (en) | 2013-03-28 | 2024-04-03 | ForSight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
WO2015031604A1 (en) | 2013-08-28 | 2015-03-05 | Crown Bioscience, Inc. | Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same |
WO2016022750A1 (en) * | 2014-08-08 | 2016-02-11 | Forsight Vision4, Inc. | Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof |
US10500091B2 (en) | 2014-11-10 | 2019-12-10 | Forsight Vision4, Inc. | Expandable drug delivery devices and methods of use |
JP6818264B2 (ja) | 2014-12-25 | 2021-01-20 | 国立大学法人京都大学 | 高密度リポタンパク質およびその細胞親和性ペプチドを融合した高密度リポタンパク質の点眼による後眼部薬物デリバリー |
CN109195556B (zh) | 2016-04-05 | 2021-03-26 | 弗赛特影像4股份有限公司 | 可植入眼睛药物递送装置 |
CN110769853B (zh) * | 2017-04-17 | 2022-06-03 | 北京生命科学研究所 | 治疗雄性衰老 |
TWI770246B (zh) * | 2017-08-02 | 2022-07-11 | 昊運股份有限公司 | 新穎化合物及包含其之醫藥組成物 |
EP3810089B1 (en) * | 2018-06-07 | 2023-08-02 | Pfizer Inc. | Aqueous formulation comprising 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea |
CN113350351A (zh) * | 2020-03-13 | 2021-09-07 | 青晓制药公司 | 帕唑帕尼的应用、药物组合物、注射液及制备方法和应用 |
USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
US20240050429A1 (en) * | 2022-08-10 | 2024-02-15 | Qx Therapeutics, Inc. | Pazopanib pharmaceutical composition, injection and preparation method and use thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8904296D0 (sv) * | 1989-12-21 | 1989-12-21 | Pharmacia Ab | Transdermal system |
US7893040B2 (en) * | 2005-07-22 | 2011-02-22 | Oculis Ehf | Cyclodextrin nanotechnology for ophthalmic drug delivery |
CA2631173A1 (en) * | 2005-11-29 | 2007-06-07 | Smithkline Beecham Corporation | Treatment method |
AR059066A1 (es) * | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
MX2008013407A (es) * | 2006-04-18 | 2009-03-09 | Ekr Therapeutics Inc | Composiciones de bolo iv premezcladas, listas para uso y metodos de uso. |
EP2209371B1 (en) * | 2007-10-19 | 2017-01-04 | SARcode Bioscience Inc. | Compositions and methods for treatment of diabetic retinopathy |
ES2494365T3 (es) * | 2008-01-30 | 2014-09-15 | Genentech, Inc. | Compuestos de pirazolopirimidina que inhiben PI3K y métodos de uso |
BR112012001030A2 (pt) * | 2009-07-16 | 2019-09-24 | Glaxo Wellcome Mfg Pte Ltd | método para tratar a degeneração macular, e, uso de um composto. |
WO2011039648A1 (en) * | 2009-09-30 | 2011-04-07 | Glaxo Wellcome Manufacturing Pte Ltd. | Methods of administration and treatment |
TW201201808A (en) * | 2010-01-06 | 2012-01-16 | Glaxo Wellcome Mfg Pte Ltd | Treatment method |
UY33367A (es) * | 2010-05-05 | 2011-10-31 | Glaxo Wellcome Mfg Pte Ltd | Composiciones farmacéuticas y métodos para su elaboración |
US20130023550A1 (en) * | 2010-05-05 | 2013-01-24 | Glaxo Wellcome Manufacturing Pte, Ltd | Pharmaceutical compositions and methods of making same |
-
2011
- 2011-05-03 UY UY0001033367A patent/UY33367A/es unknown
- 2011-05-03 AR ARP110101514A patent/AR081364A1/es unknown
- 2011-05-03 TW TW100115488A patent/TW201206908A/zh unknown
- 2011-05-05 AU AU2011247995A patent/AU2011247995B2/en not_active Ceased
- 2011-05-05 ES ES11778348.0T patent/ES2519615T3/es active Active
- 2011-05-05 EA EA201291168A patent/EA201291168A1/ru unknown
- 2011-05-05 JP JP2013509268A patent/JP5835717B2/ja not_active Expired - Fee Related
- 2011-05-05 SG SG2012079968A patent/SG185087A1/en unknown
- 2011-05-05 US US13/133,030 patent/US20120028918A1/en not_active Abandoned
- 2011-05-05 WO PCT/US2011/035363 patent/WO2011140343A1/en active Application Filing
- 2011-05-05 CA CA2798386A patent/CA2798386A1/en not_active Abandoned
- 2011-05-05 MA MA35417A patent/MA34286B1/fr unknown
- 2011-05-05 KR KR1020127031739A patent/KR20130071434A/ko not_active Application Discontinuation
- 2011-05-05 CN CN2011800333447A patent/CN102970871A/zh active Pending
- 2011-05-05 NZ NZ603411A patent/NZ603411A/en not_active IP Right Cessation
- 2011-05-05 US US13/101,689 patent/US20110281901A1/en not_active Abandoned
- 2011-05-05 MX MX2012012837A patent/MX2012012837A/es active IP Right Grant
- 2011-05-05 BR BR112012028291A patent/BR112012028291A2/pt not_active IP Right Cessation
- 2011-05-05 PE PE2012002115A patent/PE20130217A1/es not_active Application Discontinuation
- 2011-05-05 EP EP11778348.0A patent/EP2566331B1/en active Active
-
2012
- 2012-10-29 IL IL222751A patent/IL222751A0/en unknown
- 2012-10-31 CL CL2012003075A patent/CL2012003075A1/es unknown
- 2012-11-01 CR CR20120556A patent/CR20120556A/es unknown
- 2012-11-02 DO DO2012000281A patent/DOP2012000281A/es unknown
- 2012-11-02 ZA ZA2012/08265A patent/ZA201208265B/en unknown
- 2012-12-05 CO CO12221016A patent/CO6640262A2/es not_active Application Discontinuation
-
2013
- 2013-03-14 HK HK13103191.6A patent/HK1175947A1/xx not_active IP Right Cessation
-
2015
- 2015-05-06 US US14/705,298 patent/US20150231265A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20120028918A1 (en) | 2012-02-02 |
BR112012028291A2 (pt) | 2015-09-15 |
NZ603411A (en) | 2014-10-31 |
KR20130071434A (ko) | 2013-06-28 |
EP2566331A4 (en) | 2013-09-18 |
MA34286B1 (fr) | 2013-06-01 |
AU2011247995B2 (en) | 2014-07-31 |
ZA201208265B (en) | 2013-07-31 |
EP2566331B1 (en) | 2014-09-03 |
CL2012003075A1 (es) | 2013-03-08 |
US20150231265A1 (en) | 2015-08-20 |
EA201291168A1 (ru) | 2013-06-28 |
PE20130217A1 (es) | 2013-03-21 |
JP2013525501A (ja) | 2013-06-20 |
CR20120556A (es) | 2013-02-20 |
IL222751A0 (en) | 2012-12-31 |
CN102970871A (zh) | 2013-03-13 |
EP2566331A1 (en) | 2013-03-13 |
SG185087A1 (en) | 2012-12-28 |
UY33367A (es) | 2011-10-31 |
HK1175947A1 (en) | 2013-07-19 |
TW201206908A (en) | 2012-02-16 |
CA2798386A1 (en) | 2011-11-10 |
AU2011247995A1 (en) | 2012-12-13 |
JP5835717B2 (ja) | 2015-12-24 |
ES2519615T3 (es) | 2014-11-07 |
MX2012012837A (es) | 2013-01-24 |
WO2011140343A1 (en) | 2011-11-10 |
US20110281901A1 (en) | 2011-11-17 |
DOP2012000281A (es) | 2013-05-31 |
AR081364A1 (es) | 2012-08-29 |
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