CO6460778A2 - Compuestos y métodos para controlar hongos - Google Patents

Compuestos y métodos para controlar hongos

Info

Publication number
CO6460778A2
CO6460778A2 CO11156688A CO11156688A CO6460778A2 CO 6460778 A2 CO6460778 A2 CO 6460778A2 CO 11156688 A CO11156688 A CO 11156688A CO 11156688 A CO11156688 A CO 11156688A CO 6460778 A2 CO6460778 A2 CO 6460778A2
Authority
CO
Colombia
Prior art keywords
substituted
unsubstituted
alkyl
halo
alkoxy
Prior art date
Application number
CO11156688A
Other languages
English (en)
Inventor
George Davis
William Lo
James M Renga
Francis Tisdell
Maurice Yap
David Young
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of CO6460778A2 publication Critical patent/CO6460778A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Varios de los aspectos aquí descritos se relacionan con amino pirimidinas substituidas por arilo de acuerdo con laFórmula (I); en donde, X1 es N o C-R3; X2 es N o C-R4 acondición de que X1 y X2 no sean ambos N; R1-R7 son H,CN, CHO, -SCN, NO2, F, CI., Br, I, C1-C4-alquilo substituido o no substituido, halo-C1-C4-alquilo substituido o no substituido, C1-C4-aloxi substituido o no substituido, halo-C1-C4-alcoxi substituido o no substituido, C1-C4- tioalquilo substituido o no substituido, halo-C1-C4-tioalquilo substituido o no substituido, C3-C7-cicloalquilo substituido o no substituido, C2-C4-alquenilo substituido o no substituido, C2-C4-alquinilo, C1 -C4-acilalquilo substituido o no substituido, C1-C4-aciloxi, C1-C4 alcoxicarbonilo, C1-C4-alcoxi-amino, C1-C4-alquil-S(O)=NH, arilo substituido o no substituido, heterociclo substituido o no substituido, en donde los substituyentes son uno o más de los siguientes F, CI, Br, OH, CN, NO2, CHO, -SCN, S(O)n- C1-C4-alquilo (en donde n = 0-2), C1-C4-alquilo, halo-C1-C4-alquilo, C1-C4-alquilamino, C1-C4-alcoxi, halo-C1-C4-alcoxi, C1-C4- tioalquilo, halo-C1-C4-tioalquilo, C1-C4-alquilacilo, C1-C4- aciloxi, C1-C4 alcoxicarbonilo, C1-C4-alcoxi-imino, hidroxi-imino; C1-C4-alquil-S(O)=NH; y Q es un arilo substituido o no substituido, heterociclo substituido o no substituido, en donde los substituyentes de Q son tomados de R1 a R7.
CO11156688A 2009-05-19 2011-11-17 Compuestos y métodos para controlar hongos CO6460778A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17940209P 2009-05-19 2009-05-19

Publications (1)

Publication Number Publication Date
CO6460778A2 true CO6460778A2 (es) 2012-06-15

Family

ID=42315653

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11156688A CO6460778A2 (es) 2009-05-19 2011-11-17 Compuestos y métodos para controlar hongos

Country Status (24)

Country Link
US (2) US8759356B2 (es)
EP (1) EP2432767B1 (es)
JP (1) JP2012527461A (es)
KR (1) KR20120016247A (es)
CN (1) CN102438993A (es)
AU (1) AU2010250017B2 (es)
BR (1) BRPI1011058A2 (es)
CA (1) CA2760911A1 (es)
CL (1) CL2011002922A1 (es)
CO (1) CO6460778A2 (es)
CR (1) CR20110589A (es)
DK (1) DK2432767T3 (es)
EC (1) ECSP11011467A (es)
ES (1) ES2417355T3 (es)
HN (1) HN2011003040A (es)
MX (1) MX2011012343A (es)
NZ (1) NZ596123A (es)
PE (1) PE20120325A1 (es)
PL (1) PL2432767T3 (es)
PT (1) PT2432767E (es)
RU (1) RU2011151603A (es)
SI (1) SI2432767T1 (es)
TW (1) TW201041512A (es)
WO (1) WO2010135070A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX342326B (es) 2011-09-27 2016-09-26 Novartis Ag 3-pirimidin-4-il-oxazolidin-2-onas como inhibidoras de idh mutante.
UY34632A (es) 2012-02-24 2013-05-31 Novartis Ag Compuestos de oxazolidin- 2- ona y usos de los mismos
US9296733B2 (en) 2012-11-12 2016-03-29 Novartis Ag Oxazolidin-2-one-pyrimidine derivative and use thereof for the treatment of conditions, diseases and disorders dependent upon PI3 kinases
JP6387360B2 (ja) 2013-03-14 2018-09-05 ノバルティス アーゲー 変異ｉｄｈの阻害薬としての３−ピリミジン−４−イル−オキサゾリジン−２−オン

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345640A (en) * 1971-02-01 1974-01-30 Shell Int Research Piperazinyl pyrimidines
JPS6052146B2 (ja) * 1979-12-25 1985-11-18 石原産業株式会社 Ｎ−ピリジルアニリン系化合物、それらの製造方法及びそれらを含有する有害生物防除剤
FR2503162A1 (fr) * 1981-04-07 1982-10-08 Pharmindustrie Nouveaux derives de piperazino-2 pyrimidine, procedes pour leur preparation et leur utilisation comme medicaments ou comme intermediaires pour la fabrication de medicaments
ZA85853B (en) * 1984-02-17 1986-09-24 Warner Lambert Co Antibacterial agents
US4791110A (en) * 1985-06-14 1988-12-13 Eli Lilly And Company Fungicidal pyridazines
DE3922735A1 (de) * 1989-07-11 1991-01-24 Hoechst Ag Aminopyrimidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
US5792778A (en) * 1995-08-10 1998-08-11 Merck & Co., Inc. 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
AU708883B2 (en) * 1996-06-10 1999-08-12 Merck & Co., Inc. Substituted imidazoles having cytokine inhibitory activity
US6514977B1 (en) * 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
US6979686B1 (en) * 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
JP4380803B2 (ja) * 1997-06-12 2009-12-09 アベンテイス・フアルマ・リミテツド イミダゾリル−環式アセタール
DK1028950T3 (da) * 1997-10-28 2003-09-01 Warner Lambert Co 7-substituerede quinazolin-2,4-dioner nyttige som antibakterielle midler
CO5170501A1 (es) * 1999-04-14 2002-06-27 Novartis Ag AZOLES SUSTITUIDOS UTILES PARA EL TRATAMIENTO DE ENFERMEDADES MEDIADAS POR TNFa eIL-1 Y ENFERMEDADES DEL METABOLISMO OSEO
CO5210940A1 (es) * 1999-05-04 2002-10-30 Novartis Ag Compuestos plaguicidas derivados de pirimidina y composiciones que los contienen
ATE311385T1 (de) * 1999-10-27 2005-12-15 Novartis Pharma Gmbh Thiazol und imidazo(4,5-b)pyridin verbindungen und ihre verwendung als pharmazeutika
GB9927844D0 (en) 1999-11-26 2000-01-26 Glaxo Group Ltd Chemical compounds
WO2001091749A1 (en) * 2000-06-01 2001-12-06 Merck & Co., Inc. Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as jnk-inhibitors
PE20020506A1 (es) * 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
ATE274515T1 (de) * 2001-03-08 2004-09-15 Smithkline Beecham Corp Pyrazolopyridinderivate
WO2002078701A1 (en) * 2001-03-30 2002-10-10 Smithkline Beecham Corporation Use of pyrazolopyridines as therapeutic compounds
EP1372643A1 (en) * 2001-03-30 2004-01-02 Smithkline Beecham Corporation Pyrazolopyridines, process for their preparation and use as therapeutic compounds
US7196095B2 (en) * 2001-06-25 2007-03-27 Merck & Co., Inc. (Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds
JPWO2003026661A1 (ja) * 2001-09-14 2005-01-06 山之内製薬株式会社 インスリン分泌促進剤及び新規なピリミジン誘導体
US6821971B2 (en) * 2001-09-20 2004-11-23 The Procter & Gamble Company Fused pyrazolone compounds which inhibit the release of inflammatory cytokines
US6730668B2 (en) * 2001-09-20 2004-05-04 The Procter & Gamble Company 6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
CA2495386C (en) * 2002-08-14 2011-06-21 Vertex Pharmaceuticals Incorporated Protein kinase inhibitors and uses thereof
US20060102442A1 (en) * 2002-08-21 2006-05-18 Dein Kevin A Torque transmission mechanism
UA80296C2 (en) * 2002-09-06 2007-09-10 Biogen Inc Imidazolopyridines and methods of making and using the same
EP1551842A1 (en) 2002-10-15 2005-07-13 Smithkline Beecham Corporation Pyradazine compounds as gsk-3 inhibitors
JP4356504B2 (ja) * 2003-04-21 2009-11-04 田辺三菱製薬株式会社 ｐ３８ＭＡＰキナーゼ阻害剤
MXPA05012377A (es) * 2003-05-15 2006-05-25 Arqule Inc Derivados de imidazotiazoles e imidazoxazol como inhibidores de p38.
CA2531619A1 (en) * 2003-07-16 2005-01-27 Neurogen Corporation Biaryl piperazinyl-pyridine analogues
US20080058356A1 (en) * 2003-12-15 2008-03-06 Neurocrine Biosciences, Inc. 2,6 Bisheteroaryl-4-Aminopyrimidines as Adenosine Receptor Antagonists
ES2234433B1 (es) * 2003-12-15 2006-11-01 Almirall Prodesfarma, S.A. 4-aminopirimidinas como antagonistas de receptores de adenosina.
DE102004010194A1 (de) * 2004-03-02 2005-10-13 Aventis Pharma Deutschland Gmbh 4-Benzimidazol-2-yl-pyridazin-3-on-Derivate, ihre Herstellung und Verwendung in Arzneimitteln
ES2241496B1 (es) * 2004-04-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridina.
DE502005002116D1 (de) * 2004-06-25 2008-01-10 Basf Ag 2, 4, 5, 6-substituierte pyridine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen
TW200616974A (en) * 2004-07-01 2006-06-01 Astrazeneca Ab Chemical compounds
EP1804801A2 (en) * 2004-10-15 2007-07-11 Biogen Idec MA, Inc. Methods of treating vascular injuries
EP1924573A1 (en) * 2005-01-25 2008-05-28 AstraZeneca AB B-raf inhibitors
WO2006137658A1 (en) * 2005-06-20 2006-12-28 Dongbu Hitek Co., Ltd. New substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppression and inflammation inhibitory acitivity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and pharmaceutical composition comprising the same
TW200800213A (en) * 2005-09-02 2008-01-01 Abbott Lab Novel imidazo based heterocycles
JP2009523805A (ja) * 2006-01-17 2009-06-25 シグナル ファーマシューティカルズ，エルエルシー ＴＮＦα、ＰＤＥ４及びＢ−ＲＡＦの阻害剤、それらの組成物及びそれらの使用法
WO2007083692A1 (ja) * 2006-01-23 2007-07-26 Kumiai Chemical Industry Co., Ltd. アミノピリミジン誘導体及び農園芸用植物病害防除剤
RU2008152776A (ru) * 2006-06-06 2010-07-20 Эвиджен Инк. (Us) СОЕДИНЕНИЯ ЗАМЕЩЕННОГО ПИРАЗОЛО[1,5-a]ПИРИДИНА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
US7870698B2 (en) * 2006-06-27 2011-01-18 United States Gypsum Company Non-combustible reinforced cementitious lightweight panels and metal frame system for building foundations
EP2815750A1 (en) * 2006-12-21 2014-12-24 Vertex Pharmaceuticals Incorporated 5-cyano-4-(pyrrolo [2,3b] pyridine-3-yl)-pyrimidine derivatives useful as protein kinase inhibitors
WO2008080938A1 (en) * 2006-12-28 2008-07-10 Basf Se Use 2-substituted pyridines for cancer treatment
DE102007010801A1 (de) * 2007-03-02 2008-09-04 Bayer Cropscience Ag Diaminopyrimidine als Fungizide
US8603081B2 (en) * 2007-08-23 2013-12-10 Ntk Enterprises, Inc. System and method for defining and controlling LTK and other surgical eye procedures to produce little or no stromal collagen shrinkage
EA023523B1 (ru) * 2007-08-31 2016-06-30 Мартек Биосайнсиз Корпорейшн Твердые жировые композиции, содержащие полиненасыщенные жирные кислоты, и способы их получения и использования
DE102007044388B4 (de) * 2007-09-18 2012-08-02 Airbus Operations Gmbh Druckschott und Verfahren zum Unterteilen eines Luft- oder Raumfahrzeugs
US9171646B2 (en) * 2007-10-04 2015-10-27 Lawrence Livermore National Security, Llc Control of a laser inertial confinement fusion-fission power plant
US8367687B2 (en) * 2007-12-07 2013-02-05 Novartis Ag Pyrazole derivatives
CN101889012A (zh) 2007-12-12 2010-11-17 杜邦公司 杀真菌二环吡唑
DE102007061756A1 (de) * 2007-12-20 2009-06-25 Bayer Healthcare Ag Substituierte 4-Aminopyrimidin-5-carbonsäuren und ihre Verwendung
GB0725218D0 (en) * 2007-12-24 2008-02-06 Syngenta Ltd Chemical compounds
US8343966B2 (en) * 2008-01-11 2013-01-01 Novartis Ag Organic compounds
DE102008011983B4 (de) * 2008-02-29 2013-11-28 O-Flexx Technologies Gmbh Thermische Solaranlage
JP2011513385A (ja) * 2008-03-06 2011-04-28 アクテリオン ファーマシューティカルズ リミテッド 新規なピリミジン−ピリジン誘導体
TW200948362A (en) * 2008-04-09 2009-12-01 Mitsubishi Tanabe Pharma Corp New compounds and their uses
NZ589532A (en) * 2008-06-12 2012-02-24 Janssen Pharmaceutica Nv Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine H4 receptor

Also Published As

Publication number Publication date
NZ596123A (en) 2014-08-29
PL2432767T3 (pl) 2013-11-29
ECSP11011467A (es) 2011-12-30
ES2417355T3 (es) 2013-08-07
DK2432767T3 (da) 2013-09-30
EP2432767B1 (en) 2013-06-26
CR20110589A (es) 2012-03-06
CL2011002922A1 (es) 2012-04-13
US8759356B2 (en) 2014-06-24
US20100298143A1 (en) 2010-11-25
BRPI1011058A2 (pt) 2015-08-25
AU2010250017B2 (en) 2015-02-12
KR20120016247A (ko) 2012-02-23
PE20120325A1 (es) 2012-04-12
TW201041512A (en) 2010-12-01
JP2012527461A (ja) 2012-11-08
CA2760911A1 (en) 2010-11-25
CN102438993A (zh) 2012-05-02
HN2011003040A (es) 2013-10-22
EP2432767A1 (en) 2012-03-28
SI2432767T1 (sl) 2013-10-30
WO2010135070A1 (en) 2010-11-25
PT2432767E (pt) 2013-07-25
US20140275123A1 (en) 2014-09-18
AU2010250017A1 (en) 2011-11-24
MX2011012343A (es) 2011-12-14
RU2011151603A (ru) 2013-06-27

Similar Documents

Publication Publication Date Title
PH12015502525A1 (en) Ester derivatives of androgen receptor modulators and methods for their use
CY1120188T1 (el) ΠΑΡΑΓΩΓΑ ΝΑΦΘΥΡΙΔΙΝΗΣ ΧΡΗΣΙΜΑ ΩΣ ΑΝΤΑΓΩΝΙΣΤΕΣ ΙΝΤΕΓΚΡΙΝΗΣ αvβ6
CN105358522A8 (en) Ester derivatives of androgen receptor modulators and methods for their use
CR20170066A (es) Compuestos aminopirimidinilo como inhibidires de jak
PE20160523A1 (es) Derivados de arilo o heteroarilo como inhibidores de moleculas pequenas de fibrosis
CY1124537T1 (el) Παραγωγο πυριδονης που εχει τετραϋδροπυρανυλ μεθυλ ομαδα
UY35126A (es) Ojo es alfa
NZ596538A (en) Haloalkyl heteroaryl benzamide compounds
PE20080140A1 (es) DERIVADOS DE CINAMIDA MULTICICLICOS COMO INHIBIDORES DE ß AMILOIDE
CO6460778A2 (es) Compuestos y métodos para controlar hongos
ES2669189T3 (es) Compuestos de carbazol útiles como inhibidores del bromodominio
ES2553030T3 (es) Compuestos plaguicidas
MX368178B (es) Compuestos de ácido dimetilbenzoico.
MY170922A (en) Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
EA201490585A1 (ru) Производные пиперазинзамещенного бензотиофена в качестве антипсихотических агентов
MX2014002208A (es) Inhibidores de serina/treonina quinasa.
EA201171020A1 (ru) Производные бензофурана
EA201691031A1 (ru) Синтез макроциклического трипептида, ингибирующего hcv ns3
EA201592183A1 (ru) Ингибиторы bace
EA201591915A1 (ru) Соединения феноксиэтил дигидро-1h-изохинолина
EA201590561A1 (ru) Пролекарства аминохиназолинового ингибитора киназы
AR099581A1 (es) Compuestos de aminocarbonilcarbamato
CL2017000484A1 (es) Compuestos de azetidiniloxifenilpirrolidina
MX338885B (es) Compuestos utiles en la sintesis de compuestos de benzamida.
EA201591498A1 (ru) Азетидинилоксифенилпирролидиновые соединения

Legal Events

Date Code Title Description
FG Application granted