CO6270203A2 - Una solucion topica no acuosa novedosa de diclofenaco y el proceso para preparar la misma - Google Patents

Una solucion topica no acuosa novedosa de diclofenaco y el proceso para preparar la misma

Info

Publication number
CO6270203A2
CO6270203A2 CO10001093A CO10001093A CO6270203A2 CO 6270203 A2 CO6270203 A2 CO 6270203A2 CO 10001093 A CO10001093 A CO 10001093A CO 10001093 A CO10001093 A CO 10001093A CO 6270203 A2 CO6270203 A2 CO 6270203A2
Authority
CO
Colombia
Prior art keywords
diclofenac
pharmaceutically acceptable
acceptable salt
composition according
penetration enhancer
Prior art date
Application number
CO10001093A
Other languages
English (en)
Inventor
Ketan Rajnibhai Patel
Original Assignee
Troikaa Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troikaa Pharmaceuticals Ltd filed Critical Troikaa Pharmaceuticals Ltd
Publication of CO6270203A2 publication Critical patent/CO6270203A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe una composicion de solucion topica no acuosa novedosa de la sal farmacéuticamente aceptable de diclofenaco. La composicion de solucion topica no acuosa comprende la cantidad terapéuticamente efectiva de la sal farmacéuticamente aceptable de diclofenaco, solubilizante, mejorador de la penetracion y disolvente, y opcionalmente un humectante, contrairritantes, mejorador adicional de la penetracion y anti-oxidantes y un proceso para preparar la misma. 1.- Una composicion novedosa de la solucion topica no acuosa que comprende: una cantidad efectiva de sal farmacéuticamente aceptable de diclofenaco; aproximadamente 10 a 30% v/v de alcohol de cadena inferior como mejorador de la penetracion y solubilizante; un disolvente seleccionado de propilenglicol, glicofurol o su mezcla; y opcionalmente un humectante, y un mejorador de la penetracion adicional. 2.- La composicion de acuerdo con la reivindicacion 1, en donde la cantidad efectiva de sal farmacéuticamente aceptable de diclofenaco esta en el rango de aproximadamente 1.16% a aproximadamente 5% P/V, preferiblemente aproximadamente 1.16% a aproximadamente 2.32% p/v. 3.- La composicion de acuerdo con la reivindicacion 1, en donde la sal farmacéuticamente aceptable de diclofenaco es preferiblemente sal dietilamina de diclofenaco. 4.- La composicion de acuerdo con la reivindicacion 1, en donde dicho alcohol de cadena inferior tienen longitud de cadena de carbono de C2 a C5, preferiblemente seleccionado de etanol, propanol, isopropanol y mas preferiblemente etanol.5.- La composicion de acuerdo con la reivindicacion 1, en donde dicho alcohol de cadena inferior preferiblemente esta en el rango de aproximadamente 10% a 20% v/v.
CO10001093A 2007-06-08 2010-01-06 Una solucion topica no acuosa novedosa de diclofenaco y el proceso para preparar la misma CO6270203A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1092MU2007 2007-06-08

Publications (1)

Publication Number Publication Date
CO6270203A2 true CO6270203A2 (es) 2011-04-20

Family

ID=40524886

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10001093A CO6270203A2 (es) 2007-06-08 2010-01-06 Una solucion topica no acuosa novedosa de diclofenaco y el proceso para preparar la misma

Country Status (23)

Country Link
US (1) US10702469B2 (es)
EP (1) EP2211837B1 (es)
JP (2) JP5535066B2 (es)
KR (1) KR101517494B1 (es)
CN (1) CN101790370B (es)
AP (1) AP3643A (es)
AU (1) AU2008309170B2 (es)
BR (1) BRPI0811956A8 (es)
CA (1) CA2697458C (es)
CO (1) CO6270203A2 (es)
CU (1) CU23999B1 (es)
DK (1) DK2211837T3 (es)
EA (1) EA018119B1 (es)
ES (1) ES2445443T3 (es)
HK (1) HK1147066A1 (es)
IL (1) IL202009A (es)
MX (1) MX2009013352A (es)
MY (1) MY151437A (es)
PL (1) PL2211837T3 (es)
PT (1) PT2211837E (es)
UA (1) UA97529C2 (es)
WO (1) WO2009047785A2 (es)
ZA (1) ZA200908705B (es)

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US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US9308213B2 (en) 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US8895536B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating chronic inflammation and inflammatory diseases
US9737500B2 (en) 2010-10-29 2017-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
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JP2014152172A (ja) * 2013-02-08 2014-08-25 Daiya Seiyaku Kk 清涼感付与外用組成物、清涼感付与貼付剤、清涼感付与方法、清涼感付与外用組成物の製造方法、及び、清涼感付与貼付剤の製造方法
EP2961397A4 (en) * 2013-02-27 2016-11-02 Laurie Robert Batt TRANSDERMAL FORMULATIONS
JP6738120B2 (ja) * 2013-03-29 2020-08-12 小林製薬株式会社 外用医薬組成物
JP6599083B2 (ja) * 2014-03-30 2019-10-30 小林製薬株式会社 外用医薬組成物
JP6580306B2 (ja) * 2014-03-30 2019-09-25 小林製薬株式会社 外用医薬組成物
JP6580305B2 (ja) * 2014-03-30 2019-09-25 小林製薬株式会社 外用医薬組成物
JP2019510824A (ja) * 2016-03-31 2019-04-18 スマーテック・トピカル・インコーポレイテッドＳＭＡＲＴＥＣＨ ＴＯＰＩＣＡＬ，Ｉｎｃ． 送達システム
AU2018231842B2 (en) * 2017-03-07 2024-03-21 LYOTROPIC DELIVERY SYSTEMS Ltd Topical delivery systems for active compounds
JP2018030893A (ja) * 2017-11-14 2018-03-01 ダイヤ製薬株式会社 清涼感付与外用組成物の製造方法及び清涼感付与貼付剤の製造方法
EP4054549A4 (en) 2019-11-06 2023-12-06 Smartech Topical, Inc. TOPICAL FORMULATIONS OF CYCLO-OXYGENASE INHIBITORS AND THEIR USE
JP2022096997A (ja) * 2020-12-18 2022-06-30 小林製薬株式会社 外用医薬組成物
WO2023180792A1 (en) 2022-03-25 2023-09-28 Glycores 2000 Srl Topical pharmaceutical composition with anti-inflammatory and analgesic activity and uses thereof

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Also Published As

Publication number Publication date
ES2445443T3 (es) 2014-03-03
JP5734479B2 (ja) 2015-06-17
PT2211837E (pt) 2014-02-17
DK2211837T3 (da) 2014-02-10
EP2211837B1 (en) 2013-11-13
AP3643A (en) 2016-03-16
CN101790370A (zh) 2010-07-28
CA2697458A1 (en) 2009-04-16
IL202009A (en) 2015-10-29
AU2008309170A1 (en) 2009-04-16
PL2211837T3 (pl) 2014-05-30
WO2009047785A3 (en) 2009-07-02
BRPI0811956A2 (pt) 2014-11-11
KR20100047840A (ko) 2010-05-10
JP2014098046A (ja) 2014-05-29
EP2211837A2 (en) 2010-08-04
CN101790370B (zh) 2013-06-12
CU20090206A7 (es) 2011-09-21
EA018119B1 (ru) 2013-05-30
UA97529C2 (ru) 2012-02-27
CU23999B1 (es) 2014-06-27
MY151437A (en) 2014-05-30
EA200971099A1 (ru) 2010-06-30
WO2009047785A9 (en) 2010-03-11
HK1147066A1 (en) 2011-07-29
AP2010005169A0 (en) 2010-02-28
KR101517494B1 (ko) 2015-05-04
US20100120918A1 (en) 2010-05-13
WO2009047785A2 (en) 2009-04-16
CA2697458C (en) 2016-02-09
JP2010529110A (ja) 2010-08-26
MX2009013352A (es) 2010-05-21
IL202009A0 (en) 2010-06-16
AU2008309170B2 (en) 2013-03-14
BRPI0811956A8 (pt) 2015-09-22
JP5535066B2 (ja) 2014-07-02
US10702469B2 (en) 2020-07-07
ZA200908705B (en) 2010-08-25

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