BRPI0811956A8 - Solução tópica não aquosa de diclofenaco e processo para sua preparação - Google Patents
Solução tópica não aquosa de diclofenaco e processo para sua preparaçãoInfo
- Publication number
- BRPI0811956A8 BRPI0811956A8 BRPI0811956A BRPI0811956A BRPI0811956A8 BR PI0811956 A8 BRPI0811956 A8 BR PI0811956A8 BR PI0811956 A BRPI0811956 A BR PI0811956A BR PI0811956 A BRPI0811956 A BR PI0811956A BR PI0811956 A8 BRPI0811956 A8 BR PI0811956A8
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- aqueous
- topical
- solution
- diclofenac solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SOLUÇÃO TÓPICA NÃO AQUOSA DE DICLOFENACO E PROCESSO PARA SUA PREPARAÇÃO. Uma solução tópica não de sal de diclofenaco farmaceuticamente aceitável é divulgada. A composição da solução tópica não aquosa possui uma quantidade terapeuticamente eficaz de sal de diclofenaco e farmaceuticamente aceitável, solubilizante, intensificador da penetração e solvente e, opcionalmente, um umectante não irritante, um acelerador adicional da penetração e antioxidantes, bem como um processo para preparar os mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1092MU2007 | 2007-06-08 | ||
PCT/IN2008/000363 WO2009047785A2 (en) | 2007-06-08 | 2008-06-09 | A non-aqueous topical solution of diclofenac and process for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0811956A2 BRPI0811956A2 (pt) | 2014-11-11 |
BRPI0811956A8 true BRPI0811956A8 (pt) | 2015-09-22 |
Family
ID=40524886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0811956A BRPI0811956A8 (pt) | 2007-06-08 | 2008-06-09 | Solução tópica não aquosa de diclofenaco e processo para sua preparação |
Country Status (23)
Country | Link |
---|---|
US (1) | US10702469B2 (pt) |
EP (1) | EP2211837B1 (pt) |
JP (2) | JP5535066B2 (pt) |
KR (1) | KR101517494B1 (pt) |
CN (1) | CN101790370B (pt) |
AP (1) | AP3643A (pt) |
AU (1) | AU2008309170B2 (pt) |
BR (1) | BRPI0811956A8 (pt) |
CA (1) | CA2697458C (pt) |
CO (1) | CO6270203A2 (pt) |
CU (1) | CU23999B1 (pt) |
DK (1) | DK2211837T3 (pt) |
EA (1) | EA018119B1 (pt) |
ES (1) | ES2445443T3 (pt) |
HK (1) | HK1147066A1 (pt) |
IL (1) | IL202009A (pt) |
MX (1) | MX2009013352A (pt) |
MY (1) | MY151437A (pt) |
PL (1) | PL2211837T3 (pt) |
PT (1) | PT2211837E (pt) |
UA (1) | UA97529C2 (pt) |
WO (1) | WO2009047785A2 (pt) |
ZA (1) | ZA200908705B (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100099766A1 (en) * | 2008-10-16 | 2010-04-22 | Novartis Ag | Topical NSAID compositions having sensate component |
JP5650199B2 (ja) * | 2009-04-10 | 2015-01-07 | スピレイカー・インコーポレイテッドSpiracur, Inc. | 閉鎖された切開部用の陰圧閉鎖療法システムを取り付けるための方法および装置 |
US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US9737500B2 (en) | 2010-10-29 | 2017-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US8895536B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating chronic inflammation and inflammatory diseases |
US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
ITMI20121205A1 (it) | 2012-07-11 | 2014-01-12 | Glycores 2000 Srl | Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione |
JP2014152172A (ja) * | 2013-02-08 | 2014-08-25 | Daiya Seiyaku Kk | 清涼感付与外用組成物、清涼感付与貼付剤、清涼感付与方法、清涼感付与外用組成物の製造方法、及び、清涼感付与貼付剤の製造方法 |
CN114903848A (zh) * | 2013-02-27 | 2022-08-16 | 阿根塔创新有限公司 | 透皮制剂 |
JP6738120B2 (ja) * | 2013-03-29 | 2020-08-12 | 小林製薬株式会社 | 外用医薬組成物 |
JP6580306B2 (ja) * | 2014-03-30 | 2019-09-25 | 小林製薬株式会社 | 外用医薬組成物 |
JP6599083B2 (ja) * | 2014-03-30 | 2019-10-30 | 小林製薬株式会社 | 外用医薬組成物 |
JP6580305B2 (ja) * | 2014-03-30 | 2019-09-25 | 小林製薬株式会社 | 外用医薬組成物 |
JP2019510824A (ja) * | 2016-03-31 | 2019-04-18 | スマーテック・トピカル・インコーポレイテッドSMARTECH TOPICAL,Inc. | 送達システム |
CA3055159A1 (en) * | 2017-03-07 | 2018-09-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Topical delivery systems for active compounds |
JP2018030893A (ja) * | 2017-11-14 | 2018-03-01 | ダイヤ製薬株式会社 | 清涼感付与外用組成物の製造方法及び清涼感付与貼付剤の製造方法 |
CA3155267A1 (en) | 2019-11-06 | 2021-05-14 | Thomas Hnat | Topical formulations of cyclooxygenase inhibitors and their use |
JP2022096997A (ja) * | 2020-12-18 | 2022-06-30 | 小林製薬株式会社 | 外用医薬組成物 |
WO2023180792A1 (en) | 2022-03-25 | 2023-09-28 | Glycores 2000 Srl | Topical pharmaceutical composition with anti-inflammatory and analgesic activity and uses thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4353896A (en) | 1981-06-08 | 1982-10-12 | Levy Michael A | Penetrating topical medicament |
US4933184A (en) * | 1983-12-22 | 1990-06-12 | American Home Products Corp. (Del) | Menthol enhancement of transdermal drug delivery |
CA1236029A (en) * | 1984-05-14 | 1988-05-03 | Edmund Sandborn | Pharmaceutical solutions comprising dimethyl sulfoxide |
DE3522550A1 (de) | 1985-06-24 | 1987-01-02 | Klinge Co Chem Pharm Fab | Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung |
US5093133A (en) | 1990-01-24 | 1992-03-03 | Mcneil-Ppc, Inc. | Method for percutaneous delivery of ibuprofen using hydroalcoholic gel |
US5318960A (en) | 1992-06-03 | 1994-06-07 | Frank Toppo | System for transdermal delivery of pain relieving substances |
US5985860A (en) | 1992-06-03 | 1999-11-16 | Toppo; Frank | System for transdermal delivery of pain relieving substances |
US5665378A (en) * | 1994-09-30 | 1997-09-09 | Davis; Roosevelt | Transdermal therapeutic formulation |
US5654337A (en) | 1995-03-24 | 1997-08-05 | II William Scott Snyder | Topical formulation for local delivery of a pharmaceutically active agent |
US5968542A (en) * | 1995-06-07 | 1999-10-19 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system as a device |
US7833543B2 (en) * | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
EP0879597A4 (en) | 1996-02-07 | 2001-01-31 | Tsumura & Co | TRANSPARENT AQUEOUS SOLUTION OF DICLOFENAC SODIUM, MEDICINAL COMPOSITIONS, AND USES |
DE19725615A1 (de) | 1997-06-17 | 1998-12-24 | Permamed Ag | Zur topischen Applikation bestimmte Diclofenac-Lösung |
US5976566A (en) * | 1997-08-29 | 1999-11-02 | Macrochem Corporation | Non-steroidal antiinflammtory drug formulations for topical application to the skin |
US6193996B1 (en) * | 1998-04-02 | 2001-02-27 | 3M Innovative Properties Company | Device for the transdermal delivery of diclofenac |
CH693625A5 (it) * | 1999-02-18 | 2003-11-28 | Inpharma Sa | Composizioni farmaceutiche contenenti composti ad attività promotrice di assorbimento di principi attivi. |
ATE464887T1 (de) * | 2001-05-31 | 2010-05-15 | Hisamitsu Pharmaceutical Co | Perkutan resorbierbare pflaster |
US20070196453A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs |
CN102225046A (zh) * | 2005-08-05 | 2011-10-26 | 努沃研究公司 | 透皮释药剂型 |
-
2008
- 2008-06-09 EA EA200971099A patent/EA018119B1/ru unknown
- 2008-06-09 AU AU2008309170A patent/AU2008309170B2/en not_active Ceased
- 2008-06-09 ES ES08838247.8T patent/ES2445443T3/es active Active
- 2008-06-09 AP AP2010005169A patent/AP3643A/xx active
- 2008-06-09 WO PCT/IN2008/000363 patent/WO2009047785A2/en active Application Filing
- 2008-06-09 JP JP2010510963A patent/JP5535066B2/ja not_active Expired - Fee Related
- 2008-06-09 CA CA2697458A patent/CA2697458C/en active Active
- 2008-06-09 UA UAA201000120A patent/UA97529C2/ru unknown
- 2008-06-09 BR BRPI0811956A patent/BRPI0811956A8/pt not_active Application Discontinuation
- 2008-06-09 KR KR1020107000486A patent/KR101517494B1/ko active IP Right Grant
- 2008-06-09 PL PL08838247T patent/PL2211837T3/pl unknown
- 2008-06-09 PT PT88382478T patent/PT2211837E/pt unknown
- 2008-06-09 EP EP08838247.8A patent/EP2211837B1/en active Active
- 2008-06-09 MX MX2009013352A patent/MX2009013352A/es active IP Right Grant
- 2008-06-09 US US12/451,918 patent/US10702469B2/en active Active
- 2008-06-09 MY MYPI20095150 patent/MY151437A/en unknown
- 2008-06-09 CN CN2008800186179A patent/CN101790370B/zh not_active Expired - Fee Related
- 2008-06-09 DK DK08838247.8T patent/DK2211837T3/da active
-
2009
- 2009-11-09 IL IL202009A patent/IL202009A/en active IP Right Grant
- 2009-12-04 CU CU2009000206A patent/CU23999B1/es active IP Right Grant
- 2009-12-08 ZA ZA200908705A patent/ZA200908705B/xx unknown
-
2010
- 2010-01-06 CO CO10001093A patent/CO6270203A2/es not_active Application Discontinuation
-
2011
- 2011-02-07 HK HK11101163.6A patent/HK1147066A1/xx not_active IP Right Cessation
-
2014
- 2014-03-03 JP JP2014040135A patent/JP5734479B2/ja active Active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: TROIKAA PHARMACEUTICALS LTD (IN) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |