AR081870A1 - Composicion farmaceutica que comprende un derivado de amida o sal farmaceuticamente aceptable del mismo - Google Patents

Composicion farmaceutica que comprende un derivado de amida o sal farmaceuticamente aceptable del mismo

Info

Publication number
AR081870A1
AR081870A1 ARP110102036A ARP110102036A AR081870A1 AR 081870 A1 AR081870 A1 AR 081870A1 AR P110102036 A ARP110102036 A AR P110102036A AR P110102036 A ARP110102036 A AR P110102036A AR 081870 A1 AR081870 A1 AR 081870A1
Authority
AR
Argentina
Prior art keywords
pharmaceutically acceptable
pharmaceutical composition
amida
derivative
salt
Prior art date
Application number
ARP110102036A
Other languages
English (en)
Inventor
Kyeong Soo Kim
Ki Young Jang
Yo Han Kim
Jae Hyun Park
Yong Il Kim
Jong Soo Woo
Original Assignee
Hanmi Holdings Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Holdings Co Ltd filed Critical Hanmi Holdings Co Ltd
Publication of AR081870A1 publication Critical patent/AR081870A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

Esta composición, debido a la estabilidad mejorada incluso después de almacenamiento a largo plazo, es adecuada para inhibir el crecimiento de las células cancerosas.Reivindicación 1: Una composición farmacéutica caracterizada porque comprende un compuesto de fórmula (1) o una sal farmacéuticamente aceptable del mismo; y un aditivo ácido.
ARP110102036A 2010-06-11 2011-06-10 Composicion farmaceutica que comprende un derivado de amida o sal farmaceuticamente aceptable del mismo AR081870A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020100055549A KR101217526B1 (ko) 2010-06-11 2010-06-11 아마이드 유도체 또는 이의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물

Publications (1)

Publication Number Publication Date
AR081870A1 true AR081870A1 (es) 2012-10-24

Family

ID=45098550

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110102036A AR081870A1 (es) 2010-06-11 2011-06-10 Composicion farmaceutica que comprende un derivado de amida o sal farmaceuticamente aceptable del mismo

Country Status (26)

Country Link
US (1) US20130071452A1 (es)
EP (1) EP2580206B1 (es)
JP (1) JP5852105B2 (es)
KR (1) KR101217526B1 (es)
CN (1) CN102933573B (es)
AR (1) AR081870A1 (es)
AU (1) AU2011262662B2 (es)
BR (1) BR112012031510B1 (es)
CA (3) CA2801631C (es)
CL (1) CL2012003487A1 (es)
CO (1) CO6620015A2 (es)
DK (1) DK2580206T3 (es)
ES (1) ES2556457T3 (es)
HK (1) HK1181389A1 (es)
IL (1) IL223543A (es)
MA (1) MA34368B1 (es)
MX (1) MX2012014440A (es)
MY (1) MY164015A (es)
NZ (1) NZ605601A (es)
PE (1) PE20130236A1 (es)
PL (1) PL2580206T3 (es)
SG (1) SG185661A1 (es)
TW (1) TWI424995B (es)
UA (1) UA109281C2 (es)
WO (1) WO2011155793A2 (es)
ZA (1) ZA201300241B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8828391B2 (en) 2011-05-17 2014-09-09 Boehringer Ingelheim International Gmbh Method for EGFR directed combination treatment of non-small cell lung cancer
KR101317809B1 (ko) 2011-06-07 2013-10-16 한미약품 주식회사 암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물
KR20140096571A (ko) 2013-01-28 2014-08-06 한미약품 주식회사 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
TWI808958B (zh) 2017-01-25 2023-07-21 美商特普醫葯公司 涉及二芳基巨環化合物之組合療法
WO2018213770A1 (en) * 2017-05-19 2018-11-22 Regents Of The University Of Minnesota Therapeutic methods
KR102227486B1 (ko) * 2017-06-30 2021-03-12 롯데정밀화학 주식회사 프로톤 펌프 저해제를 포함하는 경구용 고형제제 조성물, 이를 포함하는 경구용 고형제제 및 그 제조방법
SG11202009498RA (en) 2018-03-27 2020-10-29 Univ Texas Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations
MX2020014105A (es) 2018-06-25 2021-05-27 Spectrum Pharmaceuticals Inc Combinacion de poziotinib con agente citotoxico y/u otro agente dirigido molecularmente y uso de esta.
US20220040180A1 (en) * 2018-09-14 2022-02-10 Spectrum Pharmaceuticals, Inc. Kits and methods for treating cancers
CN114026083A (zh) 2019-04-25 2022-02-08 德州大学系统董事会 酪氨酸激酶的杂环抑制剂
WO2020227711A1 (en) 2019-05-09 2020-11-12 FUJIFILM Cellular Dynamics, Inc. Methods for the production of hepatocytes
JP2022553744A (ja) * 2019-10-24 2022-12-26 ハンミ ファーマシューティカル カンパニー リミテッド がん細胞の成長を阻害するアミド誘導体を含む医薬調製物およびそれを含有する医薬品

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR980008219A (ko) * 1996-07-16 1998-04-30 김상응 안정화된 주사제용 약제학적 조성물
GB9718972D0 (en) * 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
CA2384291A1 (en) * 1999-09-21 2001-03-29 Astrazeneca Ab Quinazoline derivatives and their use as pharmaceuticals
DE602004004811T2 (de) * 2003-09-19 2007-11-22 Astrazeneca Ab Chinazolinderivate
GB0322409D0 (en) * 2003-09-25 2003-10-29 Astrazeneca Ab Quinazoline derivatives
MXPA06003341A (es) * 2003-09-25 2006-06-08 Astrazeneca Ab Derivados de quinazolina.
TWI377944B (en) * 2007-06-05 2012-12-01 Hanmi Holdings Co Ltd Novel amide derivative for inhibiting the growth of cancer cells
JP5649157B2 (ja) * 2009-08-01 2015-01-07 住友電気工業株式会社 半導体素子およびその製造方法

Also Published As

Publication number Publication date
RU2013100943A (ru) 2014-07-20
WO2011155793A2 (en) 2011-12-15
WO2011155793A3 (en) 2012-04-26
MX2012014440A (es) 2013-02-26
CA3127906A1 (en) 2011-12-15
EP2580206B1 (en) 2015-09-23
ES2556457T3 (es) 2016-01-18
CO6620015A2 (es) 2013-02-15
PL2580206T3 (pl) 2016-03-31
UA109281C2 (uk) 2015-08-10
CA3012771A1 (en) 2011-12-15
EP2580206A2 (en) 2013-04-17
ZA201300241B (en) 2014-03-26
JP2013531648A (ja) 2013-08-08
MA34368B1 (fr) 2013-07-03
CL2012003487A1 (es) 2013-02-22
KR20110135685A (ko) 2011-12-19
PE20130236A1 (es) 2013-03-18
AU2011262662A1 (en) 2013-01-31
US20130071452A1 (en) 2013-03-21
TW201204711A (en) 2012-02-01
IL223543A (en) 2017-02-28
TWI424995B (zh) 2014-02-01
KR101217526B1 (ko) 2013-01-02
BR112012031510A2 (pt) 2016-11-08
SG185661A1 (en) 2012-12-28
CA2801631C (en) 2018-09-04
AU2011262662B2 (en) 2015-06-25
CA2801631A1 (en) 2011-12-15
CN102933573A (zh) 2013-02-13
DK2580206T3 (en) 2016-01-11
CA3012771C (en) 2021-10-12
MY164015A (en) 2017-11-15
HK1181389A1 (en) 2013-11-08
CN102933573B (zh) 2014-12-24
EP2580206A4 (en) 2014-01-22
NZ605601A (en) 2014-11-28
BR112012031510B1 (pt) 2021-06-22
JP5852105B2 (ja) 2016-02-03

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