CO6251325A2 - Un anticuerpo humano o humanizado, o un fragmento del mismo con una region de enlace de antigeno que es especifica para dirigir la proteina al receptor de limfoproteina estromal timica humana (htslpr) - Google Patents
Un anticuerpo humano o humanizado, o un fragmento del mismo con una region de enlace de antigeno que es especifica para dirigir la proteina al receptor de limfoproteina estromal timica humana (htslpr)Info
- Publication number
- CO6251325A2 CO6251325A2 CO09144825A CO09144825A CO6251325A2 CO 6251325 A2 CO6251325 A2 CO 6251325A2 CO 09144825 A CO09144825 A CO 09144825A CO 09144825 A CO09144825 A CO 09144825A CO 6251325 A2 CO6251325 A2 CO 6251325A2
- Authority
- CO
- Colombia
- Prior art keywords
- seq
- human
- variable region
- sequence
- chain variable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1.- Un anticuerpo aislado o una porción de enlace de antígeno del mismo, el cual comprende una secuencia de la región variable de cadena pesada de la SEQ ID NO: 7 o de la SEQ ID NO: 21. 2.- Un anticuerpo aislado o una porción de enlace de antígeno del mismo, el cual comprende una secuencia de la región variable de cadena pesada de la SEQ ID NO: 7, y una secuencia de la región variable de cadena ligera de la SEQ ID NO: 8, o una secuencia de la región variable de cadena pesada de la SEQ ID NO: 21, y una secuencia de la región variable de cadena ligera de la SEQ ID NO: 22. 3.- El anticuerpo de la reivindicación 2, el cual comprende CDRH1, H2 y H3 de las SEQ ID NOs: 1, 2, y 3, respectivamente, o de las SEQ ID NOs: 15, 16, y 17, respectivamente, o una secuencia de CDRL1, L2 y L3 de las SEQ ID NOs: 4, 5, y 6, respectivamente, o de las SEQ ID NOs: 18, 19, y 20, respectivamente. 4.- El anticuerpo de la reivindicación 2, el cual comprende las CDRH1, H2 y H3 de las SEQ ID Nos: 1, 2, y 3, respectivamente, o de las SEQ ID Nos: 15, 16, y 17, respectivamente, y una secuencia de CDRL1, L2, y L3 de las SEQ ID NOs: 4, 5, y 6, respectivamente, o de las SEQ ID NO: 18, 19, y 20, respectivamente. 5.- El anticuerpo de la reivindicación 2, el cual comprende una secuencia de aminoácidos de la región variable de cadena pesada que es cuando menos el 80 por ciento idéntica a la SEQ ID NO: 7, y una secuencia de aminoácidos de la región variable de cadena ligera que es cuando menos el 80 por ciento idéntica a la SEQ ID NO: 8, o que comprende una secuencia de aminoácidos de la región variable de cadena pesada que es cuando menos el 80 por ciento idéntica a la SEQ ID NO: 21, y una secuencia de aminoácidos de la región variable de cadena ligera que es cuando menos el 80 por ciento idéntica a la SEQ ID NO: 22. 6.- El anticuerpo de la reivindicación 2, el cual es un anticuerpo quimérico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94520507P | 2007-06-20 | 2007-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6251325A2 true CO6251325A2 (es) | 2011-02-21 |
Family
ID=39846944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO09144825A CO6251325A2 (es) | 2007-06-20 | 2009-12-17 | Un anticuerpo humano o humanizado, o un fragmento del mismo con una region de enlace de antigeno que es especifica para dirigir la proteina al receptor de limfoproteina estromal timica humana (htslpr) |
Country Status (20)
Country | Link |
---|---|
US (1) | US8101182B2 (es) |
EP (1) | EP2170957A1 (es) |
JP (1) | JP2010530233A (es) |
KR (1) | KR20100034015A (es) |
CN (1) | CN102027012A (es) |
AR (1) | AR067045A1 (es) |
AU (1) | AU2008265128A1 (es) |
BR (1) | BRPI0813725A2 (es) |
CA (1) | CA2691157A1 (es) |
CL (1) | CL2008001826A1 (es) |
CO (1) | CO6251325A2 (es) |
CR (1) | CR11152A (es) |
EA (1) | EA201000006A1 (es) |
EC (1) | ECSP099812A (es) |
IL (1) | IL202573A0 (es) |
PE (1) | PE20090768A1 (es) |
TN (1) | TN2009000529A1 (es) |
TW (1) | TW200918557A (es) |
WO (1) | WO2008155365A1 (es) |
ZA (1) | ZA200908711B (es) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1129190E (pt) | 1998-11-13 | 2007-08-08 | Immunex Corp | Adn e polipéptidos de tslp humanos. |
US7288633B2 (en) | 2001-07-23 | 2007-10-30 | Immunex Corporation | Modified human thymic stromal lymphopoietin |
US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
US20090176654A1 (en) * | 2007-08-10 | 2009-07-09 | Protelix, Inc. | Universal fibronectin type III binding-domain libraries |
US7982016B2 (en) | 2007-09-10 | 2011-07-19 | Amgen Inc. | Antigen binding proteins capable of binding thymic stromal lymphopoietin |
WO2009100324A1 (en) * | 2008-02-07 | 2009-08-13 | Schering Corporation | Engineered anti-tslpr antibodies |
TW201201840A (en) * | 2010-07-15 | 2012-01-16 | Hoffmann La Roche | Antibodies specifically binding to human TSLPR and methods of use |
KR101221649B1 (ko) * | 2010-11-01 | 2013-01-14 | 광주과학기술원 | 알러지 질환의 예방 또는 치료용 약제학적 조성물, 그의 스크리닝 방법 |
RU2689528C2 (ru) * | 2013-08-09 | 2019-05-28 | Астеллас Фарма Инк. | Новое антитело к tslp-рецептору человека |
JP6640113B2 (ja) | 2014-05-07 | 2020-02-05 | アムジエン・インコーポレーテツド | 衝撃低減要素を有する自動注入器 |
JP6671298B2 (ja) | 2014-05-16 | 2020-03-25 | アムジェン インコーポレイテッド | Th1及びth2細胞集団を検出するためのアッセイ |
CA2949846C (en) | 2014-06-03 | 2023-09-05 | Amgen Inc. | Devices and methods for assisting a user of a drug delivery device |
MX2021014323A (es) | 2014-10-14 | 2023-02-02 | Amgen Inc | Dispositivo de inyección de fármaco con indicadores visuales y audibles. |
AU2015335743B2 (en) | 2014-10-23 | 2020-12-24 | Amgen Inc. | Reducing viscosity of pharmaceutical formulations |
US11357916B2 (en) | 2014-12-19 | 2022-06-14 | Amgen Inc. | Drug delivery device with live button or user interface field |
CA2976935C (en) | 2015-02-17 | 2020-03-10 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
US11806509B2 (en) | 2015-02-27 | 2023-11-07 | Amgen Inc. | Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement |
WO2017039786A1 (en) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Syringe assembly adapter for a syringe |
AU2016320748B2 (en) | 2015-09-09 | 2019-05-02 | Novartis Ag | Thymic stromal lymphopoietin (TSLP)-binding antibodies and methods of using the antibodies |
EP3347377B1 (en) | 2015-09-09 | 2021-02-17 | Novartis AG | Thymic stromal lymphopoietin (tslp)-binding antibodies and methods of using the antibodies |
JP7082568B2 (ja) | 2015-12-09 | 2022-06-08 | アムジエン・インコーポレーテツド | 信号伝達キャップ付き自動注射器 |
CN108430507B (zh) | 2015-12-18 | 2022-08-02 | 安斯泰来制药株式会社 | 含有抗人tslp受体抗体的药物组合物 |
WO2017120178A1 (en) | 2016-01-06 | 2017-07-13 | Amgen Inc. | Auto-injector with signaling electronics |
WO2017160799A1 (en) | 2016-03-15 | 2017-09-21 | Amgen Inc. | Reducing probability of glass breakage in drug delivery devices |
WO2017189089A1 (en) | 2016-04-29 | 2017-11-02 | Amgen Inc. | Drug delivery device with messaging label |
US11389588B2 (en) | 2016-05-02 | 2022-07-19 | Amgen Inc. | Syringe adapter and guide for filling an on-body injector |
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WO2017200989A1 (en) | 2016-05-16 | 2017-11-23 | Amgen Inc. | Data encryption in medical devices with limited computational capability |
EP3465124A1 (en) | 2016-06-03 | 2019-04-10 | Amgen Inc. | Impact testing apparatuses and methods for drug delivery devices |
US11285266B2 (en) | 2016-07-01 | 2022-03-29 | Amgen Inc. | Drug delivery device having minimized risk of component fracture upon impact events |
WO2018034784A1 (en) | 2016-08-17 | 2018-02-22 | Amgen Inc. | Drug delivery device with placement detection |
WO2018081234A1 (en) | 2016-10-25 | 2018-05-03 | Amgen Inc. | On-body injector |
JP2020503976A (ja) | 2017-01-17 | 2020-02-06 | アムジエン・インコーポレーテツド | 注入デバイスならびに関連する使用および組立方法 |
WO2018151890A1 (en) | 2017-02-17 | 2018-08-23 | Amgen Inc. | Drug delivery device with sterile fluid flowpath and related method of assembly |
JP7280189B2 (ja) | 2017-02-17 | 2023-05-23 | アムジエン・インコーポレーテツド | 薬物送達装置用の挿入機構 |
CA3050927A1 (en) | 2017-03-06 | 2018-09-13 | Brian Stonecipher | Drug delivery device with activation prevention feature |
US11571511B2 (en) | 2017-03-07 | 2023-02-07 | Amgen Inc. | Insertion mechanism and method of inserting a needle of a drug delivery device |
WO2018165499A1 (en) | 2017-03-09 | 2018-09-13 | Amgen Inc. | Insertion mechanism for drug delivery device |
CA3052676A1 (en) | 2017-03-28 | 2018-10-04 | Amgen Inc. | Plunger rod and syringe assembly system and method |
US20200048367A1 (en) | 2017-04-28 | 2020-02-13 | Amgen Inc. | N-acetylated and non-acetylated dipeptides containing arginine to reduce the viscosity of viscous compositions of therapeutic polypeptides |
AU2018280054B2 (en) | 2017-06-08 | 2023-07-13 | Amgen Inc. | Syringe assembly for a drug delivery device and method of assembly |
CN110709121B (zh) | 2017-06-08 | 2022-06-24 | 安进公司 | 扭矩驱动式药物递送装置 |
MA49447A (fr) | 2017-06-22 | 2020-04-29 | Amgen Inc | Réduction des impacts/chocs d'activation d'un dispositif |
EP3641861A1 (en) | 2017-06-23 | 2020-04-29 | Amgen Inc. | Electronic drug delivery device comprising a cap activated by a switch assembly |
WO2019014014A1 (en) | 2017-07-14 | 2019-01-17 | Amgen Inc. | NEEDLE INSERTION-RETRACTING SYSTEM HAVING DOUBLE TORSION SPRING SYSTEM |
MA49626A (fr) | 2017-07-21 | 2020-05-27 | Amgen Inc | Élément d'étanchéité perméable aux gaz pour récipient à médicament et procédés d'assemblage |
JP2020528296A (ja) | 2017-07-25 | 2020-09-24 | アムジエン・インコーポレーテツド | ギヤモジュールを有する薬物送達デバイス及び関連する組立方法 |
MA49676A (fr) | 2017-07-25 | 2020-06-03 | Amgen Inc | Dispositif d'administration de médicament doté d'un système d'accès à un récipient et procédé d'assemblage associé |
EP3662288B1 (en) | 2017-08-01 | 2024-02-28 | Amgen Inc. | Systems and methods for performing a real-time glycan assay of a sample |
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EP3664863A2 (en) | 2017-08-09 | 2020-06-17 | Amgen Inc. | Hydraulic-pneumatic pressurized chamber drug delivery system |
EP3668567A1 (en) | 2017-08-18 | 2020-06-24 | Amgen Inc. | Wearable injector with sterile adhesive patch |
US11103636B2 (en) | 2017-08-22 | 2021-08-31 | Amgen Inc. | Needle insertion mechanism for drug delivery device |
WO2019070472A1 (en) | 2017-10-04 | 2019-04-11 | Amgen Inc. | FLOW ADAPTER FOR MEDICATION DELIVERY DEVICE |
IL272636B1 (en) | 2017-10-06 | 2024-06-01 | Amgen Inc | Drug delivery device with combination assembly and related assembly method |
EP3694578A1 (en) | 2017-10-09 | 2020-08-19 | Amgen Inc. | Drug delivery device with drive assembly and related method of assembly |
US11826480B2 (en) | 2017-11-03 | 2023-11-28 | Amgen Inc. | Systems and approaches for sterilizing a drug delivery device |
US20200338271A1 (en) | 2017-11-06 | 2020-10-29 | Amgen Inc. | Fill-finish assemblies and related methods |
CA3079197A1 (en) | 2017-11-06 | 2019-05-09 | Amgen Inc. | Drug delivery device with placement and flow sensing |
CN116832271A (zh) | 2017-11-10 | 2023-10-03 | 安进公司 | 用于药物递送装置的柱塞 |
CA3079540A1 (en) | 2017-11-16 | 2019-05-23 | Amgen Inc. | Door latch mechanism for drug delivery device |
US20210255075A1 (en) | 2018-03-13 | 2021-08-19 | Amgen Inc. | Sequential digestion of polypeptides for mass spectrometric analysis |
US20210041453A1 (en) | 2018-03-13 | 2021-02-11 | Amgen Inc. | Methods for the preparation of trypsin-resistant polypeptides for mass spectrometric analysis |
US10835685B2 (en) | 2018-05-30 | 2020-11-17 | Amgen Inc. | Thermal spring release mechanism for a drug delivery device |
US11083840B2 (en) | 2018-06-01 | 2021-08-10 | Amgen Inc. | Modular fluid path assemblies for drug delivery devices |
WO2020009458A1 (ko) * | 2018-07-04 | 2020-01-09 | 고려대학교 세종산학협력단 | 옥사졸로퀴놀리논 유도체를 유효성분으로 포함하는 우울증 및 스트레스 관련 질환의 예방 또는 치료용 약학 조성물 |
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WO2020023220A1 (en) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Hybrid drug delivery devices with tacky skin attachment portion and related method of preparation |
EP3826699A1 (en) | 2018-07-24 | 2021-06-02 | Amgen Inc. | Delivery devices for administering drugs |
WO2020023336A1 (en) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Hybrid drug delivery devices with grip portion |
EP3829692A1 (en) | 2018-07-31 | 2021-06-09 | Amgen Inc. | Fluid path assembly for a drug delivery device |
MA53724A (fr) | 2018-09-24 | 2021-12-29 | Amgen Inc | Systèmes et procédés de dosage interventionnel |
WO2020068476A1 (en) | 2018-09-28 | 2020-04-02 | Amgen Inc. | Muscle wire escapement activation assembly for a drug delivery device |
CN112805048B (zh) | 2018-10-02 | 2023-09-22 | 安进公司 | 具有内部力传递的用于药物递送的注射系统 |
AR116607A1 (es) | 2018-10-05 | 2021-05-26 | Amgen Inc | Dispositivo de administración de fármacos con indicador de dosis |
SG11202101824VA (en) | 2018-10-15 | 2021-03-30 | Amgen Inc | Platform assembly process for drug delivery device |
AR116704A1 (es) | 2018-10-15 | 2021-06-02 | Amgen Inc | Dispositivo de administración de fármacos con mecanismo de amortiguación |
TWI831847B (zh) | 2018-11-01 | 2024-02-11 | 美商安進公司 | 部分針頭縮回之藥物遞送裝置及其操作方法 |
MA54048A (fr) | 2018-11-01 | 2022-02-09 | Amgen Inc | Dispositifs d'administration de médicament avec rétraction partielle de l'organe d'administration de médicament |
MA54057A (fr) | 2018-11-01 | 2022-02-09 | Amgen Inc | Dispositifs d'administration de médicament à rétraction partielle d'élément d'administration de médicament |
WO2020124008A1 (en) | 2018-12-14 | 2020-06-18 | Amgen Inc. | System suitability method for use with protein concentration determination by slope |
JP7483731B2 (ja) | 2019-02-14 | 2024-05-15 | アムジエン・インコーポレーテツド | 試料の調製及びその試料のリアルタイムアッセイの実施のためのシステム及び方法 |
AU2020226619A1 (en) | 2019-02-20 | 2021-08-05 | Amgen Inc. | Methods of determining protein stability |
EP3935396A1 (en) | 2019-03-04 | 2022-01-12 | Amgen Inc. | In vivo reversibility of high molecular weight species |
CA3133459A1 (en) | 2019-03-27 | 2020-10-01 | Amgen Inc. | Methods of fingerprinting therapeutic proteins via a two-dimensional (2d) nuclear magnetic resonance technique at natural abundance for formulated biopharmaceutical products |
MX2021012557A (es) | 2019-04-24 | 2021-11-12 | Amgen Inc | Conjuntos y metodos de verificacion de esterilizacion de jeringuillas. |
TW202110882A (zh) | 2019-06-04 | 2021-03-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 能結合胸腺基質淋巴細胞生成素的抗體及其應用 |
MX2021014733A (es) | 2019-06-05 | 2022-04-06 | Amgen Inc | Metodos de identificacion de atributos de proteinas terapeuticas. |
CA3148261A1 (en) | 2019-08-23 | 2021-03-04 | Amgen Inc. | Drug delivery device with configurable needle shield engagement components and related methods |
CN111171150B (zh) * | 2020-02-05 | 2020-12-08 | 北京智仁美博生物科技有限公司 | 抗人tslp抗体及其用途 |
TW202227470A (zh) | 2020-09-18 | 2022-07-16 | 美商安進公司 | 處理樣本用於肽作圖分析之方法 |
JP2023549113A (ja) | 2020-11-05 | 2023-11-22 | アムジエン・インコーポレーテツド | タンパク質を処理するための材料及び方法 |
WO2022246055A1 (en) | 2021-05-21 | 2022-11-24 | Amgen Inc. | Method of optimizing a filling recipe for a drug container |
WO2023086793A1 (en) | 2021-11-09 | 2023-05-19 | Amgen Inc. | Production of therapeutic proteins |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2323776C (en) | 1998-03-19 | 2010-04-27 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
ES2317917T3 (es) | 2000-06-28 | 2009-05-01 | Amgen Inc. | Moleculas de receptor de linfopoyetina estromal timica y sus usos de las mismas. |
AU2001271624A1 (en) | 2000-06-28 | 2002-01-08 | Whitehead Institute For Biomedical Research | Thymic stromal lymphopoietin receptor molecules and uses thereof |
US6890734B2 (en) * | 2000-11-10 | 2005-05-10 | Schering Corporation | Nucleic acids encoding a cytokine receptor complex |
NZ533987A (en) * | 2002-02-01 | 2007-04-27 | Schering Corp | Uses of mammalian cytokine; agonists and antagonists for modulating antigen presenting cell priming of T cells |
DE602004016522D1 (de) * | 2003-07-18 | 2008-10-23 | Schering Corp | Behandlung und diagnose von neoplasien mit tslp (thymic stromal lymphopoietin) |
US20050249712A1 (en) | 2004-03-23 | 2005-11-10 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Methods for use of TSLP and agonists and antagonists thereof |
EP1793856A2 (en) * | 2004-08-20 | 2007-06-13 | Amgen Inc. | Methods and compositions for treating allergic inflammation |
US20060171943A1 (en) | 2005-02-01 | 2006-08-03 | Amgen Inc. | Compositions and methods of treating fibrotic disorders |
BRPI0706530A2 (pt) * | 2006-01-13 | 2011-03-29 | Irm Llc | métodos e composições para tratamento de doenças alérgicas |
WO2009100324A1 (en) | 2008-02-07 | 2009-08-13 | Schering Corporation | Engineered anti-tslpr antibodies |
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2008
- 2008-06-18 AU AU2008265128A patent/AU2008265128A1/en not_active Abandoned
- 2008-06-18 KR KR1020107001185A patent/KR20100034015A/ko not_active Application Discontinuation
- 2008-06-18 EP EP08761179A patent/EP2170957A1/en not_active Withdrawn
- 2008-06-18 AR ARP080102594A patent/AR067045A1/es not_active Application Discontinuation
- 2008-06-18 CA CA2691157A patent/CA2691157A1/en not_active Abandoned
- 2008-06-18 JP JP2010512681A patent/JP2010530233A/ja active Pending
- 2008-06-18 PE PE2008001045A patent/PE20090768A1/es not_active Application Discontinuation
- 2008-06-18 US US12/141,516 patent/US8101182B2/en not_active Expired - Fee Related
- 2008-06-18 BR BRPI0813725-0A2A patent/BRPI0813725A2/pt not_active IP Right Cessation
- 2008-06-18 CN CN2008801025460A patent/CN102027012A/zh active Pending
- 2008-06-18 EA EA201000006A patent/EA201000006A1/ru unknown
- 2008-06-18 WO PCT/EP2008/057731 patent/WO2008155365A1/en active Application Filing
- 2008-06-19 CL CL2008001826A patent/CL2008001826A1/es unknown
- 2008-06-19 TW TW097122910A patent/TW200918557A/zh unknown
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- 2009-12-07 IL IL202573A patent/IL202573A0/en unknown
- 2009-12-08 ZA ZA200908711A patent/ZA200908711B/xx unknown
- 2009-12-09 CR CR11152A patent/CR11152A/es not_active Application Discontinuation
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AU2008265128A1 (en) | 2008-12-24 |
EA201000006A1 (ru) | 2010-10-29 |
TW200918557A (en) | 2009-05-01 |
US20090074747A1 (en) | 2009-03-19 |
PE20090768A1 (es) | 2009-07-09 |
CL2008001826A1 (es) | 2009-02-20 |
EP2170957A1 (en) | 2010-04-07 |
TN2009000529A1 (en) | 2011-03-31 |
US8101182B2 (en) | 2012-01-24 |
CR11152A (es) | 2010-01-20 |
JP2010530233A (ja) | 2010-09-09 |
AR067045A1 (es) | 2009-09-30 |
KR20100034015A (ko) | 2010-03-31 |
IL202573A0 (en) | 2011-08-01 |
WO2008155365A1 (en) | 2008-12-24 |
BRPI0813725A2 (pt) | 2014-12-30 |
ECSP099812A (es) | 2010-01-29 |
CN102027012A (zh) | 2011-04-20 |
CA2691157A1 (en) | 2008-12-24 |
ZA200908711B (en) | 2010-08-25 |
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