PE20090768A1 - Metodos y composiciones para el tratamiento de enfermedades alergicas - Google Patents
Metodos y composiciones para el tratamiento de enfermedades alergicasInfo
- Publication number
- PE20090768A1 PE20090768A1 PE2008001045A PE2008001045A PE20090768A1 PE 20090768 A1 PE20090768 A1 PE 20090768A1 PE 2008001045 A PE2008001045 A PE 2008001045A PE 2008001045 A PE2008001045 A PE 2008001045A PE 20090768 A1 PE20090768 A1 PE 20090768A1
- Authority
- PE
- Peru
- Prior art keywords
- seq
- sequence
- variable region
- nos
- chain variable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
REFERIDO A UN ANTICUERPO QUIMERICO, HUMANIZADO, O UNA PORCION DE ENLACE DE ANTIGENO, DEL ISOTIPO IgG1 O IgG4, CON UNA REGION DE ENLACE DE ANTIGENO QUE ES ESPECIFICA PARA EL RECEPTOR DE LINFOPOIETINA ESTROMAL TIMICA HUMANA (TSLP); QUE COMPRENDE UNA SECUENCIA DE LA REGION VARIABLE DE CADENA PESADA DE AL MENOS 80% IDENTICA A LA SEQ ID NO:7, Y UNA SECUENCIA DE LA REGION VARIABLE DE CADENA LIGERA DE AL MENOS 80% IDENTICA A LA SEQ ID NO:8, O QUE COMPRENDE UNA SECUENCIA DE LA REGION VARIABLE DE CADENA PESADA DE AL MENOS EL 80% IDENTICA A LA SEQ ID NO:21, Y UNA SECUENCIA DE LA REGION VARIABLE DE CADENA LIGERA DE AL MENOS EL 80% IDENTICA A LA SEQ NO:22; Y QUE COMPRENDE LAS CDRH1, CDRH2, Y CDRH3 DE LAS SEQ ID NOS: 1, 2 Y 3 RESPECTIVAMENTE, O DE LAS SEQ ID NOS: 15, 16 Y 17 RESPECTIVAMENTE; O UNA SECUENCIA DE CDRL1, CDRL2 Y CDRL3 DE LAS SEQ ID NOS: 4, 5 Y 6, RESPECTIVAMENTE, O DE LAS SEQ ID NOS: 18, 19 Y 20 RESPECTIVAMENTE. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA, UN POLINUCLEOTIDO QUE CODIFICA LA REGION VARIABLE DE LA CADENA PESADA O LIGERA Y UNA CELULA HUESPED. SIENDO UTIL PARA EL TRATAMIENTO DE DERMATITIS ATOPICA, ASMA, O RINITIS ALERGICA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94520507P | 2007-06-20 | 2007-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20090768A1 true PE20090768A1 (es) | 2009-07-09 |
Family
ID=39846944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2008001045A PE20090768A1 (es) | 2007-06-20 | 2008-06-18 | Metodos y composiciones para el tratamiento de enfermedades alergicas |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8101182B2 (es) |
| EP (1) | EP2170957A1 (es) |
| JP (1) | JP2010530233A (es) |
| KR (1) | KR20100034015A (es) |
| CN (1) | CN102027012A (es) |
| AR (1) | AR067045A1 (es) |
| AU (1) | AU2008265128A1 (es) |
| BR (1) | BRPI0813725A2 (es) |
| CA (1) | CA2691157A1 (es) |
| CL (1) | CL2008001826A1 (es) |
| CO (1) | CO6251325A2 (es) |
| CR (1) | CR11152A (es) |
| EA (1) | EA201000006A1 (es) |
| EC (1) | ECSP099812A (es) |
| IL (1) | IL202573A0 (es) |
| PE (1) | PE20090768A1 (es) |
| TN (1) | TN2009000529A1 (es) |
| TW (1) | TW200918557A (es) |
| WO (1) | WO2008155365A1 (es) |
| ZA (1) | ZA200908711B (es) |
Families Citing this family (95)
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| AU2008287426B2 (en) * | 2007-08-10 | 2014-06-26 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
| US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| US7982016B2 (en) | 2007-09-10 | 2011-07-19 | Amgen Inc. | Antigen binding proteins capable of binding thymic stromal lymphopoietin |
| AR070346A1 (es) | 2008-02-07 | 2010-03-31 | Schering Corp | Anticuerpo especifico del receptor de linfopoyetina estromal timica (tslpr) y usos en trastornos inflamatorios e inflamatorios alergicos |
| AR082163A1 (es) * | 2010-07-15 | 2012-11-14 | Hoffmann La Roche | Anticuerpos especificamente ligantes del tslpr humano y metodos de utilizacion de los mismos |
| KR101221649B1 (ko) * | 2010-11-01 | 2013-01-14 | 광주과학기술원 | 알러지 질환의 예방 또는 치료용 약제학적 조성물, 그의 스크리닝 방법 |
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| EA038462B1 (ru) | 2014-10-23 | 2021-08-31 | Эмджен Инк. | Снижение вязкости фармацевтических составов |
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| PE20181368A1 (es) | 2015-09-09 | 2018-08-27 | Novartis Ag | Moleculas de union a linfopoyetina estromal timica (tslp) y metodos de uso de las moleculas |
| MY186352A (en) | 2015-09-09 | 2021-07-15 | Novartis Ag | Thymic stromal lymphopoietin (tslp)-binding antibodies and methods of using the antibodies |
| US11351308B2 (en) | 2015-12-09 | 2022-06-07 | Amgen Inc. | Auto-injector with signaling cap |
| WO2017104778A1 (ja) | 2015-12-18 | 2017-06-22 | アステラス製薬株式会社 | 抗ヒトｔｓｌｐ受容体抗体含有医薬組成物 |
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| AU2003208888B2 (en) * | 2002-02-01 | 2006-10-19 | Merck Sharp & Dohme Llc | Uses of mammalian cytokine; related reagents |
| NZ544456A (en) * | 2003-07-18 | 2009-02-28 | Schering Corp | Treatment and diagnosis of neoplasms using thymic stromal lymphopoietin |
| US20050249712A1 (en) * | 2004-03-23 | 2005-11-10 | The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Methods for use of TSLP and agonists and antagonists thereof |
| CA2577631A1 (en) * | 2004-08-20 | 2006-03-02 | Amgen Inc. | Methods and compositions for treating allergic inflammation |
| US20060171943A1 (en) | 2005-02-01 | 2006-08-03 | Amgen Inc. | Compositions and methods of treating fibrotic disorders |
| RU2486202C2 (ru) * | 2006-01-13 | 2013-06-27 | Айрм Ллк | Антитела к рецептору тимусного стромального лимфопоэтина |
| AR070346A1 (es) | 2008-02-07 | 2010-03-31 | Schering Corp | Anticuerpo especifico del receptor de linfopoyetina estromal timica (tslpr) y usos en trastornos inflamatorios e inflamatorios alergicos |
-
2008
- 2008-06-18 AU AU2008265128A patent/AU2008265128A1/en not_active Abandoned
- 2008-06-18 KR KR1020107001185A patent/KR20100034015A/ko not_active Application Discontinuation
- 2008-06-18 JP JP2010512681A patent/JP2010530233A/ja active Pending
- 2008-06-18 EP EP08761179A patent/EP2170957A1/en not_active Withdrawn
- 2008-06-18 PE PE2008001045A patent/PE20090768A1/es not_active Application Discontinuation
- 2008-06-18 WO PCT/EP2008/057731 patent/WO2008155365A1/en active Application Filing
- 2008-06-18 CN CN2008801025460A patent/CN102027012A/zh active Pending
- 2008-06-18 BR BRPI0813725-0A2A patent/BRPI0813725A2/pt not_active IP Right Cessation
- 2008-06-18 US US12/141,516 patent/US8101182B2/en not_active Expired - Fee Related
- 2008-06-18 CA CA2691157A patent/CA2691157A1/en not_active Abandoned
- 2008-06-18 AR ARP080102594A patent/AR067045A1/es not_active Application Discontinuation
- 2008-06-18 EA EA201000006A patent/EA201000006A1/ru unknown
- 2008-06-19 CL CL2008001826A patent/CL2008001826A1/es unknown
- 2008-06-19 TW TW097122910A patent/TW200918557A/zh unknown
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2009
- 2009-12-07 IL IL202573A patent/IL202573A0/en unknown
- 2009-12-08 ZA ZA200908711A patent/ZA200908711B/xx unknown
- 2009-12-09 CR CR11152A patent/CR11152A/es not_active Application Discontinuation
- 2009-12-17 TN TNP2009000529A patent/TN2009000529A1/fr unknown
- 2009-12-17 CO CO09144825A patent/CO6251325A2/es not_active Application Discontinuation
- 2009-12-18 EC EC2009009812A patent/ECSP099812A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TN2009000529A1 (en) | 2011-03-31 |
| ECSP099812A (es) | 2010-01-29 |
| WO2008155365A1 (en) | 2008-12-24 |
| EP2170957A1 (en) | 2010-04-07 |
| TW200918557A (en) | 2009-05-01 |
| US8101182B2 (en) | 2012-01-24 |
| CA2691157A1 (en) | 2008-12-24 |
| IL202573A0 (en) | 2011-08-01 |
| EA201000006A1 (ru) | 2010-10-29 |
| CL2008001826A1 (es) | 2009-02-20 |
| AU2008265128A1 (en) | 2008-12-24 |
| JP2010530233A (ja) | 2010-09-09 |
| BRPI0813725A2 (pt) | 2014-12-30 |
| ZA200908711B (en) | 2010-08-25 |
| CR11152A (es) | 2010-01-20 |
| US20090074747A1 (en) | 2009-03-19 |
| AR067045A1 (es) | 2009-09-30 |
| KR20100034015A (ko) | 2010-03-31 |
| CO6251325A2 (es) | 2011-02-21 |
| CN102027012A (zh) | 2011-04-20 |
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