CO6210756A2 - La proteina linfopoyetina estromal timica canina y usos de la misma - Google Patents
La proteina linfopoyetina estromal timica canina y usos de la mismaInfo
- Publication number
- CO6210756A2 CO6210756A2 CO09062338A CO09062338A CO6210756A2 CO 6210756 A2 CO6210756 A2 CO 6210756A2 CO 09062338 A CO09062338 A CO 09062338A CO 09062338 A CO09062338 A CO 09062338A CO 6210756 A2 CO6210756 A2 CO 6210756A2
- Authority
- CO
- Colombia
- Prior art keywords
- tslp
- seq
- protein
- amino acid
- antigenic fragment
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102100031294 Thymic stromal lymphopoietin Human genes 0.000 abstract 16
- 239000012634 fragment Substances 0.000 abstract 8
- 230000000890 antigenic effect Effects 0.000 abstract 7
- 241000282465 Canis Species 0.000 abstract 6
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 108010029307 thymic stromal lymphopoietin Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/43—Sweetening agents, e.g. thaumatin, monellin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5418—IL-7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5418—IL-7
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/20—Dermatological disorders
- G01N2800/202—Dermatitis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Botany (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87513506P | 2006-12-14 | 2006-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6210756A2 true CO6210756A2 (es) | 2010-10-20 |
Family
ID=39430681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO09062338A CO6210756A2 (es) | 2006-12-14 | 2009-06-16 | La proteina linfopoyetina estromal timica canina y usos de la misma |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US7718772B2 (enExample) |
| EP (1) | EP2104683B1 (enExample) |
| JP (4) | JP2010512744A (enExample) |
| KR (1) | KR101525631B1 (enExample) |
| CN (2) | CN101631800B (enExample) |
| AU (1) | AU2007334531B2 (enExample) |
| BR (1) | BRPI0720001A2 (enExample) |
| CA (1) | CA2671865C (enExample) |
| CO (1) | CO6210756A2 (enExample) |
| ES (1) | ES2582655T3 (enExample) |
| IL (2) | IL199170A (enExample) |
| IN (1) | IN2009CN03372A (enExample) |
| MX (1) | MX2009006470A (enExample) |
| NZ (1) | NZ578352A (enExample) |
| RU (2) | RU2457217C2 (enExample) |
| UA (3) | UA120027C2 (enExample) |
| WO (1) | WO2008076255A2 (enExample) |
| ZA (1) | ZA200904152B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101631800B (zh) | 2006-12-14 | 2012-12-05 | 先灵-普劳有限公司 | 犬胸腺基质淋巴细胞生成素蛋白及其应用 |
| JP5492158B2 (ja) | 2011-08-24 | 2014-05-14 | 富士フイルム株式会社 | ヒトｔｓｈ及び犬ｔｓｈに対する抗体 |
| US9546219B2 (en) | 2012-02-08 | 2017-01-17 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
| AR090915A1 (es) | 2012-05-04 | 2014-12-17 | Intervet Int Bv | Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg |
| WO2014162007A2 (en) * | 2013-04-04 | 2014-10-09 | Ieo - Istituto Europeo Di Oncologia Srl | Thymic stromal lymphopoietin fragments and uses thereof |
| AR097293A1 (es) * | 2013-08-09 | 2016-03-02 | Astellas Pharma Inc | Anticuerpo contra el receptor de tslp humana |
| RU2732604C2 (ru) | 2013-12-20 | 2020-09-21 | Интервет Интернэшнл Б.В. | Антитела к pd-1 собак |
| WO2015118124A1 (en) * | 2014-02-06 | 2015-08-13 | Vib Vzw | Thymic stromal lymphopoietin receptor antagonist |
| RU2736732C2 (ru) | 2015-04-02 | 2020-11-19 | Интервет Интернэшнл Б.В. | Антитела к альфа-рецептору собачьего интерлейкина-4 |
| EA038332B1 (ru) | 2015-09-09 | 2021-08-10 | Новартис Аг | Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул |
| RU2731644C2 (ru) | 2015-09-09 | 2020-09-07 | Новартис Аг | Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул |
| CA3005696A1 (en) | 2015-12-18 | 2017-06-22 | Intervet International B.V. | Caninized human antibodies to human and canine il-4r alpha |
| US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
| WO2018089335A1 (en) | 2016-11-09 | 2018-05-17 | North Carolina State University | Treatment of allergic diseases with chimeric protein |
| WO2019183437A1 (en) | 2018-03-23 | 2019-09-26 | North Carolina State University | Methods and compositions for antibody to high affinity receptor for ige |
| CN115028722B (zh) * | 2021-03-05 | 2024-09-03 | 拜西欧斯（北京）生物技术有限公司 | 抗tslp抗体及其制备方法和用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| ZA887773B (en) | 1987-10-26 | 1989-07-26 | Immunex Corp | Interleukin-7 |
| US5714585A (en) * | 1987-10-26 | 1998-02-03 | Sterling Winthrop, Inc. | Antibodies that are immunoreactive with interleukin-7 |
| US5413914A (en) * | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US6844170B1 (en) * | 1998-03-19 | 2005-01-18 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
| US20030099947A1 (en) * | 1998-09-21 | 2003-05-29 | Bazan J. Fernando | Mammalian cytokines; related reagents and methods |
| IL143034A0 (en) * | 1998-11-13 | 2002-04-21 | Immunex Corp | Human tslp dna and polypeptides |
| WO2000039149A2 (en) | 1998-12-30 | 2000-07-06 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| GB9908533D0 (en) * | 1999-04-14 | 1999-06-09 | Novartis Ag | Organic compounds |
| JP2004519205A (ja) * | 2000-06-28 | 2004-07-02 | アムジェン インコーポレイテッド | 胸腺間質リンホポイエチンレセプター分子およびその使用 |
| US6890734B2 (en) * | 2000-11-10 | 2005-05-10 | Schering Corporation | Nucleic acids encoding a cytokine receptor complex |
| CA2532595A1 (en) * | 2003-07-18 | 2005-01-27 | Schering Corporation | Treatment and diagnosis of neoplasms using thymic stromal lymphopoietin |
| US20090156467A1 (en) * | 2004-07-28 | 2009-06-18 | Zhengbin Yao | Thymic stromal lymphpoietin promoter and use therefor |
| SE532251C2 (sv) | 2006-11-28 | 2009-11-24 | Theravac Pharmaceuticals Ab | Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering |
| CN101631800B (zh) * | 2006-12-14 | 2012-12-05 | 先灵-普劳有限公司 | 犬胸腺基质淋巴细胞生成素蛋白及其应用 |
-
2007
- 2007-12-11 CN CN2007800512690A patent/CN101631800B/zh active Active
- 2007-12-11 UA UAA201412004A patent/UA120027C2/uk unknown
- 2007-12-11 UA UAA200907400A patent/UA95329C2/ru unknown
- 2007-12-11 US US11/954,143 patent/US7718772B2/en active Active
- 2007-12-11 BR BRPI0720001-3A2A patent/BRPI0720001A2/pt not_active Application Discontinuation
- 2007-12-11 CN CN201210044325.0A patent/CN102584998B/zh active Active
- 2007-12-11 UA UAA201103603A patent/UA108064C2/uk unknown
- 2007-12-11 JP JP2009541349A patent/JP2010512744A/ja active Pending
- 2007-12-11 CA CA2671865A patent/CA2671865C/en active Active
- 2007-12-11 ES ES07867705.1T patent/ES2582655T3/es active Active
- 2007-12-11 WO PCT/US2007/025318 patent/WO2008076255A2/en not_active Ceased
- 2007-12-11 MX MX2009006470A patent/MX2009006470A/es active IP Right Grant
- 2007-12-11 IN IN3372CHN2009 patent/IN2009CN03372A/en unknown
- 2007-12-11 NZ NZ578352A patent/NZ578352A/en not_active IP Right Cessation
- 2007-12-11 RU RU2009126617/10A patent/RU2457217C2/ru active
- 2007-12-11 KR KR1020097014362A patent/KR101525631B1/ko active Active
- 2007-12-11 AU AU2007334531A patent/AU2007334531B2/en active Active
- 2007-12-11 EP EP07867705.1A patent/EP2104683B1/en active Active
-
2009
- 2009-06-04 IL IL199170A patent/IL199170A/en not_active IP Right Cessation
- 2009-06-12 ZA ZA2009/04152A patent/ZA200904152B/en unknown
- 2009-06-16 CO CO09062338A patent/CO6210756A2/es not_active Application Discontinuation
-
2010
- 2010-03-10 US US12/721,002 patent/US8076456B2/en active Active
-
2011
- 2011-10-03 IL IL215507A patent/IL215507A0/en unknown
- 2011-11-11 US US13/294,680 patent/US8791242B2/en active Active
-
2012
- 2012-02-14 JP JP2012029831A patent/JP2012090647A/ja active Pending
- 2012-04-05 RU RU2012113162A patent/RU2617957C2/ru active
- 2012-11-30 JP JP2012262329A patent/JP5707380B2/ja active Active
-
2014
- 2014-12-26 JP JP2014265708A patent/JP6117767B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |