CN101631800B - 犬胸腺基质淋巴细胞生成素蛋白及其应用 - Google Patents

犬胸腺基质淋巴细胞生成素蛋白及其应用 Download PDF

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CN101631800B
CN101631800B CN2007800512690A CN200780051269A CN101631800B CN 101631800 B CN101631800 B CN 101631800B CN 2007800512690 A CN2007800512690 A CN 2007800512690A CN 200780051269 A CN200780051269 A CN 200780051269A CN 101631800 B CN101631800 B CN 101631800B
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tslp
ala
protein
arg
canine
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CN101631800A (zh
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J·D·马特森
D·M·戈曼
R·德瓦尔马莱菲特
M·A·莫西
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Intervet International BV
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先灵-普劳有限公司
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    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/43—Sweetening agents, e.g. thaumatin, monellin
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    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
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    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
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    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5418—IL-7
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/20—Dermatological disorders
    • G01N2800/202—Dermatitis

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  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2007800512690A 2006-12-14 2007-12-11 犬胸腺基质淋巴细胞生成素蛋白及其应用 Active CN101631800B (zh)

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CN201210044325.0A CN102584998B (zh) 2006-12-14 2007-12-11 犬胸腺基质淋巴细胞生成素蛋白及其应用

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US87513506P 2006-12-14 2006-12-14
US60/875,135 2006-12-14
PCT/US2007/025318 WO2008076255A2 (en) 2006-12-14 2007-12-11 Canine thymic stromal lymphopoietin protein and uses thereof

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US (3) US7718772B2 (enExample)
EP (1) EP2104683B1 (enExample)
JP (4) JP2010512744A (enExample)
KR (1) KR101525631B1 (enExample)
CN (2) CN102584998B (enExample)
AU (1) AU2007334531B2 (enExample)
BR (1) BRPI0720001A2 (enExample)
CA (1) CA2671865C (enExample)
CO (1) CO6210756A2 (enExample)
ES (1) ES2582655T3 (enExample)
IL (2) IL199170A (enExample)
IN (1) IN2009CN03372A (enExample)
MX (1) MX2009006470A (enExample)
NZ (1) NZ578352A (enExample)
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UA (3) UA108064C2 (enExample)
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CN102584998B (zh) 2006-12-14 2017-07-04 英特维特国际股份有限公司 犬胸腺基质淋巴细胞生成素蛋白及其应用
JP5492158B2 (ja) 2011-08-24 2014-05-14 富士フイルム株式会社 ヒトｔｓｈ及び犬ｔｓｈに対する抗体
WO2013119419A1 (en) 2012-02-08 2013-08-15 North Carolina State University Treatment of allergic diseases with recombinant antibodies
AR090915A1 (es) * 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
JP2016522165A (ja) * 2013-04-04 2016-07-28 イエオ−イスティトゥート・エウロペオ・ディ・オンコロジア・エッセ・エッレ・エッレ 胸腺間質性リンパ球新生因子フラグメント及びその使用
TWI635097B (zh) * 2013-08-09 2018-09-11 日商安斯泰來製藥股份有限公司 新穎抗人類ｔｓｌｐ受體抗體
BR112016014284A2 (pt) 2013-12-20 2017-12-05 Intervet Int Bv anticorpo caninizado isolado ou um fragmento de ligação de antígeno do mesmo, ácido nucleico isolado, vetor de expressão, célula hospedeira, composição farmacêutica, e, métodos para aumentar a atividade de uma célula imune e para produzir um anticorpo caninizado ou fragmento de ligação de antígeno do mesmo
WO2015118124A1 (en) * 2014-02-06 2015-08-13 Vib Vzw Thymic stromal lymphopoietin receptor antagonist
CN113861294B (zh) 2015-04-02 2024-03-08 英特维特国际股份有限公司 针对犬白介素-4受体α的抗体
EA038332B1 (ru) 2015-09-09 2021-08-10 Новартис Аг Молекулы, связывающиеся с тимусным стромальным лимфопоэтином (tslp), и способы применения таких молекул
CU24533B1 (es) 2015-09-09 2021-07-02 Novartis Ag Anticuerpos o fragmentos de los mismos que se unen a linfopoyetina estromal tímica (tslp) y composiciones farmacéuticas de los mismos
US11091556B2 (en) 2015-12-18 2021-08-17 Intervet Inc. Caninized human antibodies to human IL-4R alpha
PT3390451T (pt) 2015-12-18 2025-03-12 Intervet Int Bv Anticorpos humanos caninizados para il-4r alfa humano e canino
EP3538558A4 (en) 2016-11-09 2020-07-15 North Carolina State University TREATMENT OF ALLERGIC DISEASES USING CHIMERIC PROTEIN
US12060437B2 (en) 2018-03-23 2024-08-13 North Carolina State University Methods and compositions for antibody to high affinity receptor for IgE
CN115028722B (zh) * 2021-03-05 2024-09-03 拜西欧斯（北京）生物技术有限公司 抗tslp抗体及其制备方法和用途

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AU2007334531A1 (en) 2008-06-26
AU2007334531B2 (en) 2012-04-12
JP2015107121A (ja) 2015-06-11
RU2617957C2 (ru) 2017-04-28
US20110033478A1 (en) 2011-02-10
RU2012113162A (ru) 2013-10-20
IL199170A (en) 2015-04-30
UA108064C2 (uk) 2015-03-25
KR20090097921A (ko) 2009-09-16
WO2008076255A3 (en) 2008-09-18
US20080152620A1 (en) 2008-06-26
IN2009CN03372A (enExample) 2015-08-07
JP6117767B2 (ja) 2017-04-19
US8791242B2 (en) 2014-07-29
BRPI0720001A2 (pt) 2013-12-24
ZA200904152B (en) 2011-11-30
KR101525631B1 (ko) 2015-06-04
CN102584998A (zh) 2012-07-18
JP5707380B2 (ja) 2015-04-30
JP2010512744A (ja) 2010-04-30
UA95329C2 (ru) 2011-07-25
WO2008076255A2 (en) 2008-06-26
CO6210756A2 (es) 2010-10-20
IL215507A0 (en) 2011-11-30
US7718772B2 (en) 2010-05-18
MX2009006470A (es) 2009-06-26
CA2671865A1 (en) 2008-06-26
UA120027C2 (uk) 2019-09-25
JP2012090647A (ja) 2012-05-17
JP2013048637A (ja) 2013-03-14
EP2104683A2 (en) 2009-09-30
US8076456B2 (en) 2011-12-13
EP2104683B1 (en) 2016-05-25
CN102584998B (zh) 2017-07-04
NZ578352A (en) 2012-05-25
ES2582655T3 (es) 2016-09-14
CN101631800A (zh) 2010-01-20
RU2009126617A (ru) 2011-01-20
RU2457217C2 (ru) 2012-07-27
US20130183291A1 (en) 2013-07-18
CA2671865C (en) 2017-01-10

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